Although the involvement of infection/inflammation in the pathogenesis of Tourette's syndrome has been discussed, antipsychotics are still the first choice in pharmacotherapy (1). Haloperidol and pimozide are well-established therapies (2), but increasing literature on this topic points out the advantages of atypical antipsychotics, at least regarding side effects (3, 4). ++++Afterward, we started treatment with 10 mg/day of aripiprazole because of the side effect profile. In the first week, Ms. A's motor and vocal tics showed a marked improvement; after 2 weeks, Ms. A was nearly tic free for the first time in 13 years.