Results from the ELUTES (European evaLUation of pacliTaxel-Eluting Stent) and ASPECT (A paclitaxel-eluting Stent for the PrEvention of Coronary restenosis Trial) dose-finding studies showed a significant dose-dependent decrease in late loss and restenosis rate with nonpolymeric paclitaxel-coated stents in patients with single de novo coronary lesions.