Joint pain without swelling, warmth, redness or systemic manifestations such as fever. It may be a manifestation of degenerative joint conditions (osteo-arthrosis) or of many local and systemic diseases, in which arthralgia may be an early manifestation. Arthralgia may follow injury to the joint, e.g. work, play, position during sleep often accompanied by painful muscle spasm around the affected joint. Several joints may be affected.