The effortful, sparse output was due to an anterior extension of the lesion into the deep white matter of the left hemisphere near the central nuclei, particularly the lenticular nucleus (...). Descending motor fibers in this area were injured by this extension of the lesion, causing the speech disorder typical of anterior lesions. Marie called this disorder an "anarthria". He named the area where a lesion caused anarthria the "lenticular zone" or "quadrilateral space".