The orbitofrontal cortex is a part of the frontal lobe that lies on the roof of the orbit. Because of its functions in emotion, the orbitofrontal cortex is considered to be a part of the limbic system.Classic clinical evidence suggests that the orbitofrontal cortex is involved in critical human functions, such as social adjustment and the control of mood, drive and responsibility, traits that are crucial in defining the ‘personality’ of an individual.