Adermin, 3-hydroxg-4, 5-bis (hidroxy-methyl)-2- methylpyryriduine, (CH2OH)2 C5 HN (OH) (CH3). A factor, deficiency of which causes in rats a florid symetrical dermatitis of the extremities, epileptiform and haematuria. Similar deficiency effects are seen in pigs and chicks, but little is known about its relation to human nutrition.