Physical exercise, fitness and dietary pattern and their relationship with circadian blood pressure pattern, augmentation index and endothelial dysfunction biological markers : EVIDENT study protocol
García Ortiz, Luis (Sanidad de Castilla y Léon)
Recio Rodríguez, José I. (Sanidad de Castilla y Léon)
Martín Cantera, Carlos (Institut Català de la Salut)
Cabrejas Sánchez, Alfredo (Servicio de Salud de Castilla-La Mancha)
Gómez Arranz, Amparo (Sanidad de Castilla y Léon)
González Viejo, Natividad (Servicio Aragonés de Salud)
Iturregui San Nicolás, Eguskiñe (Osakidetza Servicio Vasco de Salud)
Patino Alonso, María C. (Sanidad de Castilla y Léon)
Gómez Marcos, Manuel A. (Sanidad de Castilla y Léon)
Red de Investigación en Actividades Preventivas y Promoción de la Salud. EVIDENT Group

Fecha: 2010
Resumen: Background: Healthy lifestyles may help to delay arterial aging. The purpose of this study is to analyze the relationship of physical activity and dietary pattern to the circadian pattern of blood pressure, central and peripheral blood pressure, pulse wave velocity, carotid intima-media thickness and biological markers of endothelial dysfunction in active and sedentary individuals without arteriosclerotic disease. Methods/Design Design: A cross-sectional multicenter study with six research groups. Subjects: From subjects of the PEPAF project cohort, in which 1,163 who were sedentary became active, 1,942 were sedentary and 2,346 were active. By stratified random sampling, 1,500 subjects will be included, 250 in each group. Primary measurements: We will evaluate height, weight, abdominal circumference, clinical and ambulatory blood pressure with the Radial Pulse Wave Acquisition Device (BPro), central blood pressure and augmentation index with Pulse Wave Application Software (A-Pulse) and SphymgoCor System Px (Pulse Wave Analysis), pulse wave velocity (PWV) with SphymgoCor System Px (Pulse Wave Velocity), nutritional pattern with a food intake frequency questionnaire, physical activity with the 7-day PAR questionnaire and accelerometer (Actigraph GT3X), physical fitness with the cycle ergometer (PWC-170), carotid intima-media thickness by ultrasound (Micromax), and endothelial dysfunction biological markers (endoglin and osteoprotegerin). Discussion: Determining that sustained physical activity and the change from sedentary to active as well as a healthy diet improve circadian pattern, arterial elasticity and carotid intima-media thickness may help to propose lifestyle intervention programs. These interventions could improve the cardiovascular risk profile in some parameters not routinely assessed with traditional risk scales. From the results of this study, interventional approaches could be obtained to delay vascular aging that combine physical exercise and diet.
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès.
Documento: article ; publishedVersion
Publicado en: BMC Public health, Vol. 10, N. 233 (May 2010) , p. 1-8, ISSN 1471-2458

PMID: 20459634

8 p, 647.4 KB

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