Genomic scan for quantitative trait loci of chemical and physical body composition and deposition on pig chromosome X including the pseudoautosomal region of males
Duthie, Carol-Anne (Scottish Agricultural College (Edimburg, Regne Unit))
Simm, Geoff (Scottish Agricultural College (Edimburg, Regne Unit))
Perez-Enciso, Miguel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Doeschl-Wilson, Andrea (Scottish Agricultural College (Edimburg, Regne Unit))
Kalm, Ernst (Christian-Albrechts-University of Kiel. Institute of Animal Breeding and Husbandry)
Knap, Pieter W. (PIC Germany (Schleswig, Alemanya))
Roehe, Rainer (Scottish Agricultural College (Edimburg, Regne Unit))

Fecha:	2009
Resumen:	A QTL analysis of pig chromosome X (SSCX) was carried out using an approach that accurately takes into account the specific features of sex chromosomes i. e. their heterogeneity, the presence of a pseudoautosomal region and the dosage compensation phenomenon. A three-generation full-sib population of 386 animals was created by crossing Pietrain sires with a crossbred dam line. Phenotypic data on 72 traits were recorded for at least 292 and up to 315 F2 animals including chemical body composition measured on live animals at five target weights ranging from 30 to 140 kg, daily gain and feed intake measured throughout growth, and carcass characteristics obtained at slaughter weight (140 kg). Several significant and suggestive QTL were detected on pig chromosome X: (1) in the pseudoautosomal region of SSCX, a QTL for entire loin weight, which showed paternal imprinting, (2) closely linked to marker SW2456, a suggestive QTL for feed intake at which Pietrain alleles were found to be associated with higher feed intake, which is unexpected for a breed known for its low feed intake capacity, (3) at the telomeric end of the q arm of SSCX, QTL for jowl weight and lipid accretion and (4) suggestive QTL for chemical body composition at 30 kg. These results indicate that SSCX is important for physical and chemical body composition and accretion as well as feed intake regulation.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Documento:	Article ; Versió publicada
Publicado en:	Genetics, selection, evolution, Vol. 41, N. 27 (March 2009) , p. 1-9, ISSN 1297-9686

DOI: 10.1186/1297-9686-41-27
PMID: 19284590

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