Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
Nadal Reus, Jeroni (Universitat Autònoma de Barcelona)
Figueroa, Marta S. (Vissum Madrid)
Carreras Bertran, Elisa (Universitat Autònoma de Barcelona)
Pujol Gomis, Patrícia (Universitat Autònoma de Barcelona)
Canut, Maria Isabel (Universitat Autònoma de Barcelona)
Barraquer, Rafael I. (Rafael Ignasi) (Universitat Autònoma de Barcelona)

Data:	2015
Resum:	To evaluate the anatomical and functional results obtained with pars plana vitrectomy (PPV) plus autologous platelet concentrate (APC) as a treatment for macular detachment associated with optic disc pit (ODP). We performed a prospective interventional study of 19 eyes of 19 consecutive patients with posterior macular detachment due to ODP. All patients underwent PPV, posterior hyaloid peeling, fluid-air exchange, injection of 0. 05 mL of APC over the ODP and 15% perfluoropropane (C3F8) endotamponade. Postoperative measures included face-up positioning for 2 hours and then avoidance of the face-up position during the ensuing 10 days. All patients underwent complete ophthalmologic examination and optical coherence tomography preoperatively at 1 month, 3 months, 6 months, 9 months, and 12 months postoperatively and then annually. Outcome measures were best corrected visual acuity (BCVA) by logMAR, improvement of quality of vision, macular attachment, and resolution of intraretinal schisis-like separation. Preoperatively, the median BCVA was 0. 70 (range: 0. 30-1. 70) and all patients showed improved visual acuity after surgery; BCVA was 0. 22 (range: 0. 07-0. 52) at 12 months follow-up. All patients showed complete reabsorption of intraretinal fluid (median time: 3. 5 months [range: 2-8 months]) and macular attachment at the end of follow-up (median: 60 months [range: 12-144 months]), with stable or improved visual acuity. No reoperations were needed and no major adverse events were recorded. For macular detachment associated with ODP, the combination of PPV, posterior hyaloid peeling, APC, and C3F8 tamponade is a highly effective alternative technique with stable anatomical and functional results.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Macular detachment ; Optic disc pit ; Maculopathy ; Retinoschisis ; Pars plana vitrectomy ; Autologous platelet concentrate
Publicat a:	Clinical Ophthalmology (Auckland, N.Z.), Vol. 9 (October 2015) , p. 1965-1971, ISSN 1177-5483

DOI: 10.2147/OPTH.S81976
PMID: 26543348

7 p, 1.2 MB

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