L1CAM expression in endometrial carcinomas : an ENITEC collaboration study
van der Putten, Louis J. M. (Department of Obstetrics and Gynaecology, Radboud University Medical Center)
Visser, Nicole C. M. (Department of Pathology, Radboud University Medical Center)
van de Vijver, Koen (Department of Pathology, Anthoni van Leeuwenhoek Hospital)
Santacana, Maria (Institut de Recerca Biomèdica de Lleida)
Bronsert, Peter (Institute of Pathology, University Medical Center Freiburg)
Bulten, Johan (Department of Pathology, Radboud University Medical Center)
Hirschfeld, Marc (German Cancer Research Center (DKFZ))
Colás Ortega, Eva (Vall d'Hebron Institut de Recerca (VHIR))
Gil-Moreno, Antonio 1965- (Vall d'Hebron Institut de Recerca (VHIR))
Garcia, Angel (Hospital Universitari Vall d'Hebron)
Mancebo, Gemma (Hospital del Mar (Barcelona, Catalunya))
Alameda, Francesc (Hospital del Mar (Barcelona, Catalunya))
Trovik, Jone (Haukeland University Hospital (Bergen, Noruega))
Kopperud, Reidun K. (Center for Cancer Biomarkers (CCBIO), University of Bergen)
Huvila, Jutta (University of Turku. Department of Pathology)
Schrauwen, Stefanie (University Hospitals Gasthuisberg (Leuven, Bélgica))
Koskas, Martin (Department of Obstetrics and Gynecology, Bichat-Claude Bernard Hospital)
Walker, Francine (Department of Pathology, Bichat-Claude Bernard Hospital)
Weinberger, Vit (Department of Gynecology and Obstetrics, Faculty of Medicine, Masaryk University)
Minar, Lubos (Department of Gynecology and Obstetrics, Faculty of Medicine, Masaryk University)
Jandakova, Eva (Institute of Pathology, Faculty of Medicine, Masaryk University)
Snijders, Marc P. L. M. (Department of Obstetrics and Gynaecology, Canisius-Wilhelmina Hospital)
van den Berg-van Erp, Saskia (Department of Pathology, Canisius-Wilhelmina Hospital)
Matías-Guiu, Xavier (Institut de Recerca Biomèdica de Lleida)
Salvesen, Helga B. (Haukeland University Hospital (Bergen, Noruega))
Amant, Frederic (University Hospitals Gasthuisberg (Leuven, Bélgica))
Massuger, Leon FAG. (Department of Obstetrics and Gynaecology, Radboud University Medical Center)
Pijnenborg, Johanna M. A. (Department of Obstetrics and Gynaecology, TweeSteden Hospital)
Universitat Autònoma de Barcelona

Data:	2016
Resum:	Identification of aggressive endometrioid endometrial carcinomas (EECs) and non-endometrioid carcinomas (NEECs) is essential to improve outcome. L1 cell adhesion molecule (L1CAM) expression is a strong prognostic marker in stage I EECs, but less is known about L1CAM expression in advanced-stage EECs and NEECs. This study analyses L1CAM expression in a clinically representative cohort of endometrial carcinomas. The expression of L1CAM was immunohistochemically determined in 1199 endometrial carcinomas, treated at one of the European Network for Individualized Treatment of Endometrial Cancer (ENITEC) centres. Staining was considered positive when.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Endometrial cancer ; Endometrioid ; Non-endometrioid ; L1CAM ; Immunohistochemistry
Publicat a:	British journal of cancer, Vol. 115 (08 2016) , p. 716-724, ISSN 1532-1827

DOI: 10.1038/bjc.2016.235
PMID: 27505134

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