Web of Science: 6 citations, Scopus: 9 citations, Google Scholar: citations,
Individual signatures and environmental factors shape skin microbiota in healthy dogs
Cuscó, Anna
Belanger, Janelle M.
Gershony, Liza
Islas-Trejo, Alma
Levy, Kerinne
Medrano, Juan F.
Sánchez, Armand (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Oberbauer, Anita M.
Francino, Olga (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular)

Date: 2017
Abstract: The individual, together with its environment, has been reported as the main force driving composition and structure of skin microbiota in healthy dogs. Therefore, one of the major concerns when analyzing canine skin microbiota is the likely influence of the environment. Despite the dense fur covering, certain skin diseases exhibit differential prevalence among skin sites, dog breeds, and individuals. We have characterized the normal variability of dog skin microbiota in a well-controlled cohort of a large number of Golden-Labrador Retriever crossed dogs (N = 35) with similar ages, related genetic background, and a shared environment. We found that the individual drives the skin microbiota composition and structure followed by the skin site. The main bacterial classes inhabiting dog skin in this cohort are Gammaproteobacteria and Bacilli. We also detected bacteria associated to the environment on different dog skin sites that could be reflecting the different degrees of exposure of each skin site and each dog. Network analyses elucidated bacterial interactions within and between skin sites, especially in the chin, abdomen, axilla, and perianal region, with the highly shared interactions probably representing an anatomical, behavioral, or environmental component. When analyzing each skin site independently to assess host-specific factors, we found that temporality (season of birth and time spent in the kennel) affected all the skin sites and specially the inner pinna. The most abundant taxon driving this difference was Sphingomonas. We also found taxonomic differences among male and female dogs on the abdomen, axilla, and back. We observed a large inter-individual variability and differences among skin sites. Host-specific variables, such as temporality or sex, were also shaping skin microbiota of healthy dogs, even in an environmental homogenous cohort. The online version of this article (10. 1186/s40168-017-0355-6) contains supplementary material, which is available to authorized users.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès.
Document: article ; recerca ; publishedVersion
Subject: Skin ; Canine ; Microbiota ; Microbiome ; Dog ; Season ; Skin site ; Pinna ; 16S ; Environment
Published in: Microbiome, Vol. 5 (october 2017) , ISSN 2049-2618

PMID: 29029635
DOI: 10.1186/s40168-017-0355-6

15 p, 1.5 MB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2018-02-08, last modified 2018-11-14

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