Is systematic training in opioid overdose prevention effective?
Espelt, Albert 1981- (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Bosque Prous, Marina (Agència de Salut Pública de Barcelona)
Folch, Cinta (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya)
Sarasa Renedo, Ana (Instituto de Salud Carlos III. Programa de Epidemiología Aplicada y de Campo (PEAC))
Majó, Xavier (Generalitat de Catalunya. Departament de Salut)
Casabona-Barbarà, Jordi (Generalitat de Catalunya. Departament de Salut)
Brugal, María Teresa (Agència de Salut Pública de Barcelona)
Esteve, Anna
Montoliu, Alexandra
Muñoz, Rafa
González Soler, Victoria
Ausina, Vicente
Vecino, Carmen
Colom, Joan (Colom Farran)
Meroño, Mercè
Altabas, Anna

Date:	2017
Abstract:	The objectives were to analyze the knowledge about overdose prevention, the use of naloxone, and the number of fatal overdoses after the implementation of Systematic Training in Overdose Prevention (STOOP) program. We conducted a quasi-experimental study, and held face-to-face interviews before (n = 725) and after (n = 722) implementation of systematic training in two different samples of people who injected opioids attending harm reduction centers. We asked participants to list the main causes of overdose and the main actions that should be taken when witnessing an overdose. We created two dependent variables, the number of (a) correct and (b) incorrect answers. The main independent variable was Study Group: Intervention Group (IG), Comparison Group (CG), Pre-Intervention Group With Sporadic Training in Overdose Prevention (PREIGS), or Pre-Intervention Group Without Training in Overdose Prevention (PREIGW). The relationship between the dependent and independent variables was assessed using a multivariate Poisson regression analysis. Finally, we conducted an interrupted time series analysis of monthly fatal overdoses before and after the implementation of systematic program during the period 2006-2015. Knowledge of overdose prevention increased after implementing systematic training program. Compared to the PREIGW, the IG gave more correct answers (IRR = 1. 40;95%CI:1. 33-1. 47), and fewer incorrect answers (IRR = 0. 33;95%CI:0. 25-0. 44). Forty percent of people who injected opioids who received a naloxone kit had used the kit in response to an overdose they witnessed. These courses increase knowledge of overdose prevention in people who use opioids, give them the necessary skills to use naloxone, and slightly diminish the number of fatal opioid overdoses in the city of Barcelona.
Grants:	Ministerio de Economía y Competitividad RD12/0028/0018
Note:	Altres ajuts: RD06/0001/1018
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Adult ; Analgesics ; Opioids ; Drug overdose ; Harm reduction ; Health education ; Health knowledge ; Interviews as topic ; Multivariate analysis ; Naloxone ; Narcotic antagonists ; Opioid-related disorders ; Program evaluation ; Regression analysis ; Risk factors ; Spain
Published in:	PloS one, Vol. 12, núm. 10 (october 2017) , p. e0186833, ISSN 1932-6203

DOI: 10.1371/journal.pone.0186833
PMID: 29088247

14 p, 1.7 MB

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