Web of Science: 1 citas, Scopus: 2 citas, Google Scholar: citas,
Genetic alterations that do or do not occur naturally : consequences for genome edited organisms in the context of regulatory oversight
Custers, René (Vlaams Instituut voor Biotechnologie)
Casacuberta i Suñer, Josep M. (Centre de Recerca en Agrigenòmica)
Eriksson, Dennis (Sveriges Lantbruksuniversitet)
Sági, László (Magyar Tudományos Akadémiát. Mezőgazdasági Kutatóközpont)
Schiemann, Joachim (Julius Kühn-Institut. Federal Research Centre for Cultivated Plants)

Fecha: 2019
Resumen: The ability to successfully exploit genome edited organisms for the benefit of food security and the environment will essentially be determined by the extent to which these organisms fall under specific regulatory provisions. In many jurisdictions the answer to this question is considered to depend on the genetic characteristics of the edited organism, and whether the changes introduced in its genome do (or do not) occur naturally. We provide here a number of key considerations to assist with this evaluation as well as a guide of concrete examples of genetic alterations with an assessment of their natural occurrence. These examples support the conclusion that for many of the common types of alterations introduced by means of genome editing, the resulting organisms would not be subject to specific biosafety regulatory provisions whenever novelty of the genetic combination is a crucial determinant.
Nota: This work was supported by the Swedish Foundation for Strategic Environmental Research (Mistra) through the Mistra Biotech research program.
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès.
Documento: article ; recerca ; publishedVersion
Materia: Genome editing ; Regulatory oversight ; Natural genetic alterations ; GMO ; Classification ; Future policy
Publicado en: Frontiers in Bioengineering and Biotechnology, Vol. 6 (Jan. 2019) , art. 213, ISSN 2296-4185

DOI: 10.3389/fbioe.2018.00213
PMID: 30701172

7 p, 145.7 KB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias > CRAG (Centro de Investigación en Agrigenómica)
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 Registro creado el 2019-06-17, última modificación el 2019-07-15

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