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Comparison of Insulin Determination on NiNPs/chitosan- MWCNTs and NiONPs/chitosan-MWCNTs Modified Pencil Graphite Electrode
Šišoláková, Ivana (University of P.J. Šafárik in Košice. Department of Physical Chemistry)
Hovancová, Jana (University of P.J. Šafárik in Košice. Department of Physical Chemistry)
Oriňaková, Renáta (University of P.J. Šafárik in Košice. Department of Physical Chemistry)
Oriňak, Andrej (University of P.J. Šafárik in Košice. Department of Physical Chemistry)
Rueda García, Daniel (Institut Català de Nanociència i Nanotecnologia)
Shylenko, Oleg (University of P.J. Šafárik in Košice)
Radoňák, Jozef (University of P.J. Šafárik in Košice)

Data: 2019
Resum: The rising amount of patients suffering for diabetes mellitus increases the requirements for effective insulin sensors. Carbon materials are a suitable choice for the development of insulin sensors due to their electrochemical characteristics. Pencil graphite electrodes (PGE) represent the trade-off between price and excellent conductive properties. The modification of PGE by NiO and Ni nanoparticles fixed by chitosan results in surface area enlargement and improved electrocatalytic properties. This paper is focused on the comparison of different properties of Ni and NiO nanoparticles and their effect on redox reaction mechanism of insulin and detection characteristics. The electrode modified by Ni nanoparticles displays linear range of 1 μM-5 μM (R 0. 80), limit of detection (LOD) of 4. 34 μM and sensitivity of 0. 12 μA/μM. On the other hand, the electrode modified by NiO nanoparticles displays enhanced electrochemical characteristics such as linear range of 0. 05 μM-5 μM (R 0. 99), limit of detection of 260 nM and sensitivity of 0. 64 μA/μM. These properties make the NiO nanoparticles modified PGE the appropriate candidate for insulin determination.
Drets: Tots els drets reservats.
Llengua: Anglès
Document: Article ; recerca ; Versió sotmesa a revisió
Matèria: Insulin ; Electrochemical determination ; Pencil graphite electrodes ; Nickel nanoparticles ; Nickel oxide nanoparticles
Publicat a: Electroanalysis, Vol. 31, Issue 1 (January 2019) , p. 103-112, ISSN 1521-4109

DOI: 10.1002/elan.201800483


Preprint
13 p, 525.4 KB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > Institut Català de Nanociència i Nanotecnologia (ICN2)
Articles > Articles de recerca
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 Registre creat el 2019-09-02, darrera modificació el 2022-09-10



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