Google Scholar: cites
TEMPRANILLO is a direct repressor of the microRNA miR172
Aguilar Jaramillo, Andrea Elizabeth (Centre de Recerca en Agrigenòmica)
Marín González, Esther (Centre de Recerca en Agrigenòmica)
Matías Hernández, Luis (Centre de Recerca en Agrigenòmica)
Osnato, Michela (Centre de Recerca en Agrigenòmica)
Pelaz Herrero, Soraya (Centre de Recerca en Agrigenòmica)
Suárez-López, Paula (Centre de Recerca en Agrigenòmica)

Data: 2019
Resum: In the age-dependent pathway, microRNA 156 (miR156) is essential for the correct timing of developmental transitions. miR156 negatively regulates several SPL genes, which promote the juvenile-to-adult and floral transitions in part through upregulation of miR172. The transcriptional repressors TEMPRANILLO1 (TEM1) and TEM2 delay flowering in Arabidopsis thaliana at least through direct repression of FLOWERING LOCUS T (FT) and gibberellin biosynthetic genes, and have also been reported to participate in the length of the juvenile phase. Levels of TEM mRNA and miR156 decrease gradually, allowing progression through developmental phases. Given these similarities, we hypothesized that TEMs and the miR156/SPL/miR172 module could act through a common genetic pathway. We analyzed the effect of TEMs on levels of miR156, SPL and miR172, tested binding of TEMs to these genes using chromatin immunoprecipitation and analyzed the genetic interaction between TEMs and miR172. We found that TEMs played a stronger role in the floral transition than in the juvenile-to-adult transition. TEM1 repressed MIR172A, MIR172B and MIR172C expressions and bound in vivo to at least MIR172C sequences. Genetic analyses indicated that TEMs affect the regulation of developmental timing through miR172.
Ajuts: Ministerio de Economía y Competitividad BFU2015-64409-P
Ministerio de Economía y Competitividad BFU2012-33746
Ministerio de Economía y Competitividad CSD2007-00036
Agència de Gestió d'Ajuts Universitaris i de Recerca 2014/SGR-1406
Drets: Tots els drets reservats
Llengua: Anglès
Document: Article ; recerca ; Versió acceptada per publicar
Matèria: Rabidopsis ; Flowering ; Juvenile-to-adult transition ; MiR172 ; SPL ; TEMPRANILLO ; Vegetative phase change
Publicat a: The Plant Journal, Vol. 100, Issue 3 (November 2019) , p. 522-535, ISSN 0960-7412

DOI: 10.1111/tpj.14455
PMID: 31310397

34 p, 6.1 MB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > CRAG (Centre de Recerca en Agrigenòmica)
Articles > Articles de recerca
Articles > Articles publicats

 Registre creat el 2019-10-25, darrera modificació el 2022-04-01

   Favorit i Compartir