Status and Prospects of systems biology in grapevine research
Matus, José Tomás (Universitat de València. Institut de Biologia Integrativa de Sistemes)
Ruggieri, Valentino (Centre de Recerca en Agrigenòmica)
Romero, Francisco José (Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial)
Moretto, Marco (Fondazione Edmund Mach. Centro Ricerca e Innovazione)
Wong, Darren Chern Jan (Australian National University. Research School of Biology)

Publicació:	[s. l.] : Springer, 2019
Descripció:	30 pàg.
Resum:	The cultivated grapevine, Vitis vinifera L. , has gathered a vast amount of omics data throughout the last two decades, driving the imperative use of computational resources for its analysis and integration. Molecular systems biology arises from this need allowing to model and predict the emergence of phenotypes or responses in biological systems. Beyond single omics networks, integrative approaches associate the molecular components of an organism and combine them into higher order networks to model dynamic behaviors. Application of network-based methods in multi-omics data is providing additional resources to address important questions regarding grapevine fruit quality and composition. Here, we review the recent history of systems biology in this species. We highlight the most relevant aspects of the discipline and describe important integrative studies that have helped in the global understanding of how this species responds to the environment and how it triggers the fruit ripening developmental program. We also highlight the latest resources that are available for the grapevine community to exploit and take advantage of all the omics data that is being generated.
Ajuts:	Ministerio de Ciencia e Innovación PGC2018-099449-A-I00 Ministerio de Ciencia e Innovación RYC-2017-23645
Drets:	Tots els drets reservats.
Llengua:	Anglès
Col·lecció:	Compendium of Plant Genomes
Document:	Capítol de llibre ; Versió acceptada per publicar
Matèria:	Integrative analysis ; Regulatory network ; Gene co-expression ; Multi-omics
Publicat a:	The Grape Genome, 2019, p. 137-166, ISBN 978-3-030-18601-2

DOI: 10.1007/978-3-030-18601-2_8

Post-print 65 p, 1.6 MB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > CRAG (Centre de Recerca en Agrigenòmica)
Llibres i col·leccions > Capítols de llibres