Quantitative Morphological Variation in the Developing Drosophila Wing
Matamoro-Vidal, Alexis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Huang, Yunxian (University of Helsinki. Institute of Biotechnology)
Salazar Ciudad, Isaac (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Shimmi, Osamu (University of Helsinki. Institute of Biotechnology)
Houle, David (Florida State University. Department of Biological Science)

Data:	2018
Resum:	Quantitative genetic variation in morphology is pervasive in all species and is the basis for the evolution of differences among species. The measurement of morphological form in adults is now beginning to be combined with comparable measurements of form during development. Here we compare the shape of the developing wing to its adult form in a holometabolous insect, Drosophila melanogaster. We used protein expression patterns to measure shape in the developing precursors of the final adult wing. Three developmental stages were studied: late larval third instar, post-pupariation and in the adult fly. We studied wild-type animals in addition to mutants of two genes ( and ) that have known effects on adult wing shape and size. Despite experimental noise related to the difficulty of comparing developing structures, we found consistent differences in wing shape and size at each developmental stage between genotypes. Quantitative comparisons of variation arising at different developmental stages with the variation in the final structure enable us to determine when variation arises, and to generate hypotheses about the causes of that variation. In addition we provide linear rules allowing us to link wing morphology in the larva, with wing morphology in the pupa. Our approach provides a framework to analyze quantitative morphological variation in the developing fly wing. This framework should help to characterize the natural variation of the larval and pupal wing shape, and to measure the contribution of the processes occurring during these developmental stages to the natural variation in adult wing morphology.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Dachsous ; Geometric Morphometrics ; Organ shape ; Shifted ; Wing morphogenesis
Publicat a:	G3, Vol. 8, Issue 7 (June 2018) , p. 2399-2409, ISSN 2160-1836

DOI: 10.1534/g3.118.200372
PMID: 29844017

11 p, 1.8 MB

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