Influenza H1N1 virus-associated pneumonia often resembles rapidly progressive interstitial lung disease seen in collagen vascular diseases and COVID-19 pneumonia; CT-pathologic correlation in 24 patients
Murota, Makiko (Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan)
Johkoh, Takeshi (Department of Radiology, Kansai Rosai Hospital, Hyogo, Japan)
Lee, Kyung Soo (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea)
Franquet, Tomas (Institut d'Investigació Biomèdica Sant Pau)
Kondoh, Yasuhiro (Department of Respiratory and Allergic Medicine, Tosei General Hospital, Aichi, Japan)
Nishiyama, Yoshihiro (Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan)
Tanaka, Tomonori (Department of Pathology, Kindai University Faculty of Medicine, Osaka, Japan)
Sumikawa, Hiromitsu (Department of Radiology, Sakai City Medical Center, Osaka, Japan)
Egashira, Ryoko (Department of Radiology, Faculty of Medicine, Saga University, Saga, Japan)
Yamaguchi, Norihiko (Department of Respiratory Medicine, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Hyogo, Japan)
Fujimoto, Kiminori (Department of Radiology, Kurume University School of Medicine, Fukuoka, Japan)
Fukuoka, Junya (Department of Laboratory of Pathology, Nagasaki University Hospital, Nagasaki, Japan)
Universitat Autònoma de Barcelona

Data:	2020
Resum:	To describe computed tomography (CT) findings of influenza H1N1 virus-associated pneumonia (IH1N1VAP), and to correlate CT findings to pathological ones. The study included 24 patients with IH1N1VAP. Two observers independently evaluated the presence, distribution, and extent of CT findings. CT features were divided into either classical form (C-form) or non-classical form (NC-form). C-form included: A. ) broncho-bronchiolitis and bronchopneumonia type, whereas NC-forms included: B. ) diffuse peribronchovascular type, simulating subacute rheumatoid arthritis-associated (RA) interstitial lung disease (ILD) and C. ) lower peripheral and/or peribronchovascular type, resembling dermatomyositis-associated ILD and COVID-19 pneumonia. In 10 cases with IH1N1VAP where lung biopsy was performed, CT and pathology findings were correlated. The most common CT findings were ground-glass opacities (24/24, 100 %) and airspace consolidation (23/24, 96 %). C-form was found in 11 (46 %) patients while NC-form in 13 (54 %). Types A, B, and C were seen in 11(46 %), 4 (17 %), and 9 (38 %) patients, respectively. The lung biopsy revealed organizing pneumonia in all patients and 6 patients (60 %) showed incorporated type organizing pneumonia that was common histological findings of rapidly progressive ILD. In almost half of patients of IH1N1VAP, CT images show NC-form pneumonia pattern resembling either acute or subacute RA or dermatomyositis-associated ILD and COVID-19 pneumonia.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Influenza A (H1N1) virus ; Computed tomography ; Pneumonia ; Myositis and muscle disease ; Rheumatoid arthritis ; COVID-19
Publicat a:	European Journal of Radiology Open, Vol. 7 (november 2020) , ISSN 2352-0477

DOI: 10.1016/j.ejro.2020.100297
PMID: 33318970

7 p, 3.4 MB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
Articles > Articles de recerca
Articles > Articles publicats