Meaning in life : resilience beyond reserve
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann)
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann)
Solana, Javier (Institut Germans Trias i Pujol)
Tormos, Josep M. (Universitat Autònoma de Barcelona)
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann)

Data:	2018
Resum:	The contribution of psychological factors to brain health and resilience remains poorly investigated. Furthermore, their possible interaction with 'classical' cognitive reserve (CR) estimates in predicting perceived mental health and cognitive status has not been specifically addressed. We obtained data from 1081 adults responding to questionnaires on the three meaning in life (MiL) dimensions: purpose in life (PiL), sense of coherence (SoC), and engagement with life (EwL). A questionnaire on CR variables was also administered. The outcome measures were self-reported cognitive function and affective status (depression, stress, and anxiety). Multiple linear regression analyses were used to evaluate the association between sociodemographic variables, MiL dimensions, and CR with the two selected outcomes. Mediation analyses, adjusted for age and gender, were applied to determine whether the MiL dimensions mediated the putative effects of CR on self-reported mental and cognitive health. All three MiL components, but not CR estimates, correlated with the self-reported affective status of the participants. Higher CR, PiL, and SoC (but not EwL) scores significantly correlated with higher perceived cognitive function. Notably, the observed association between the CR measures and self-reported cognitive function was mediated by PiL and SoC. Psychological MiL dimensions mediate the association between classic CR estimates and self-perceived cognitive function. Further studies on CR could consider including formal measures of such psychological factors to better understand their unique or synergistic contributions, as well as investigate the associated mechanisms maintaining brain function at older ages. The online version of this article (10. 1186/s13195-018-0381-z) contains supplementary material, which is available to authorized users.
Nota:	The research received funding from 'La Caixa' Foundation (grant agreement n° LCF/PR/PR16/11110004).
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Cognitive reserve ; Meaning in life ; Sense of coherence ; Purpose in life ; Cognition ; Affective status
Publicat a:	Alzheimer's research & therapy, Vol. 10 (may 2018) , ISSN 1758-9193

DOI: 10.1186/s13195-018-0381-z
PMID: 29793549

10 p, 891.8 KB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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