Nutritional Status According to the GLIM Criteria in Patients with Chronic Heart Failure : association with Prognosis
Joaquín, Clara (Universitat Autònoma de Barcelona. Departament de Medicina)
Alonso Pedrol, Núria (Universitat Autònoma de Barcelona. Departament de Medicina)
Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina)
Gastelurrutia, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Pérez-Montes de Oca, Alejandra (Universitat Autònoma de Barcelona. Departament de Medicina)
Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Zamora, Elisabet (Universitat Autònoma de Barcelona. Departament de Medicina)
Socias, Guillem (Universitat Autònoma de Barcelona. Departament de Medicina)
Ramos, Analía (Universitat Autònoma de Barcelona. Departament de Medicina)
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina)

Data:	2022
Resum:	Background: The Global Leadership Initiative on Malnutrition (GLIM) criteria were recently proposed to build a global consensus on the diagnostic criteria for malnutrition. This study aimed to evaluate the GLIM criteria for its prognostic significance in outpatients with heart failure (HF), and to compare them to a previous validated method, such as the Mini Nutritional Assessment (MNA). Methods: This was a post hoc observational analysis of a prospectively recruited cohort, which included 151 subjects that attended an outpatient HF clinic. At baseline, all patients completed the nutritional screening MNA short form and the nutritional assessment MNA. In a post hoc analysis, we evaluated the GLIM criteria at baseline. The outcomes were based on data from a five-year follow-up. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular (CV) mortality and recurrent HF-related hospitalizations. We also investigated whether the GLIM criteria had better prognostic power than the MNA. Results: Abnormal nutritional status was identified in 19. 8% of the patients with the GLIM criteria and in 25. 1% with the MNA. In the multivariate analyses (age, sex, NYHA functional class, diabetes, and Barthel index), nutritional status assessed by the MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalizations during the five-year follow-up. Conclusions: Malnutrition assessed by MNA, but not by the GLIM criteria, was an independent predictor of all-cause mortality, CV mortality, and recurrent HF-related hospitalization in our cohort of outpatients with HF.
Ajuts:	Ministerio de Economía y Competitividad RD16/0011/0006 Ministerio de Economía y Competitividad CB16/11/00403
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; Versió publicada
Matèria:	MNA ; GLIM criteria ; Heart failure ; Prognosis ; CV mortality
Publicat a:	Nutrients, Vol. 14 Núm. 11 (2022) , p. 2244, ISSN 2072-6643

DOI: 10.3390/nu14112244
PMID: 35684044

12 p, 1.4 MB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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