Web of Science: 3 citations, Scopus: 3 citations, Google Scholar: citations
Plasma-Ionized Magnesium in Hospitalized Horses with Gastrointestinal Disorders and Systemic Inflammatory Response Syndrome
Sanmartí, Julia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Armengou Ruiz, Lara (Universitat Autònoma de Barcelona. Fundació Hospital Clínic Veterinari)
Troya-Portillo, Lucas (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Robles-Guirado, José-Ángel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Bassols Teixidó, Anna Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Ríos, José (Universitat Autònoma de Barcelona. Departament de Medicina)
José Cunilleras, Eduard (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Date: 2022
Abstract: Magnesium disorders in horses with gastrointestinal disorders or systemic inflammatory response syndrome (SIRS) are scarcely characterized. The purpose of the study was to explore the association of magnesium disorders with diagnosis, SIRS and mortality in horses admitted to a referral equine hospital. In total, 75 sick horses were included in an observational prospective study and classified as: obstructive (n = 17), inflammatory (n = 10) and ischemic gastrointestinal disorders (n = 12), and other non-gastrointestinal systemic disorders (n = 36). All sick horses were also divided according to the presence (n = 26) or absence of SIRS, and survival to discharge from hospital (survivors (n = 61) and non-survivors (n = 14). In addition, 26 horses were included as controls. On admission, mean (iMg) (95% confidence interval (CI)) in the SIRS group (0. 47 (0. 43-0. 50 mmol/L)) was within the normal range (0. 4-0. 6 mmol/L). The obstructive group had lower (iMg) compared to the control group (0. 44 (0. 38-0. 51 mmol/L) vs. 0. 56 (0. 50-0. 61 mmol/L); p = 0. 001). In total, 8 out of 17 (47%) horses with obstructive lesions presented with hypomagnesemia compared to controls (4% (1/26)) (p = 0. 001). In conclusion, hypomagnesemia was more prevalent on admission in horses in the obstructive group, and to a lesser extent, in the inflammatory and ischemic groups. In contrast to human ICU patients, the proportion of hospitalized horses with hypomagnesemia was not associated with mortality.
Note: Altres ajuts: Nova Biomedical Corporation
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: Article ; recerca ; Versió publicada
Subject: Hypomagnesemia ; Hypocalcemia ; Gastrointestinal disorders ; Electrolytes ; Equine
Published in: Animals, Vol. 12 Núm. 12 (6-2 2022) , p. 1479, ISSN 2076-2615

DOI: 10.3390/ani12121479
PMID: 35739816


10 p, 776.3 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Grup de Recerca Malalties infeccioses-inflamatòries en animals de companyia (MIAC)
Articles > Research articles
Articles > Published articles

 Record created 2022-06-22, last modified 2023-04-19



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