Descriptive analyses of maternally-derived antibody levels against porcine circovirus 2 (PCV-2) in 3- and 21-day-old piglets from farms of four European countries using different vaccination protocols in sows
Sibila, Marina (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Fablet, Christelle (Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail)
Faderl, M. (Veterinary Pig Practice Scheidegg)
Ferrari, Luca (Veterinary Pig Practice Scheidegg)
Rose, Nicolas (Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail)
Palzer, Andreas (Veterinary Pig Practice Scheidegg)
Martelli, Paolo (Università degli Studi di Parma)
Venegas-Vargas, María Cristina (Zoetis Inc.)
Fredrickson, Dan (Zoetis Inc.)
Taylor, Lucas Pare (Zoetis Inc.)
Balasch, Monica (Zoetis Inc.)
Bandrick, Meggan (Zoetis Inc.)
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Llorens, Anna M. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Huerta, Eva (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)

Data:	2022
Resum:	Background: Up to now, information on the levels of maternally-derived antibodies (MDA) against PCV-2 in suckling piglets born to sows vaccinated with different strategies is scarce in the literature. In the present observational study, the PCV-2-specific MDA titres from piglets from 109 farms (thirty 3-day-old and thirty 21-day-old piglets per farm) across four different European countries (France n = 30, Germany n = 27, Italy n = 22 and Spain n = 30) using different sow vaccination strategies (during gestation, as a gilt, as a piglet or never) were assessed. Results: In all four countries, mean log PCV-2 MDA titres were higher in 3-day-old piglets than in the 3-week-old ones, being significant in most of all the comparisons performed. Within each country, the highest PCV-2-specific MDA titres were observed in the 3-day-old piglets born to sows vaccinated during gestation. Indeed, in the four countries, more than 60% of this subpopulation (3-day-old piglets from sows vaccinated during pregnancy) had the highest log PCV-2 titres detectable with the ELISA technique used in this study. The lowest MDA titres were more variable. Whereas in France and Germany the lowest titres corresponded to 21-day-old piglets born from sows vaccinated as a piglet, in Italy, they corresponded to 21-day-old piglets derived from sows vaccinated as a gilt and in Spain to 21-day-old piglets born from non-vaccinated sows. In this study, PCV-2-specific MDA titres at 3 and 21 days of age were not affected by sow parity. Conclusions: Data obtained could be considered as a European global overview of PCV-2-specific MDA titres present in the pre-vaccinated piglet populations in different European countries, with titres tending to be higher in younger piglets, but with values variable among countries and sow vaccination strategies.
Nota:	Funding Information: The authors would like to acknowledge the farmers and practitioners for their willingness to participate in this study. Moreover, we are very grateful to F. Eono and E. Eveno from France, P. Borghetti, E. De Angelis and A. Caleffi from Italy and P. Pleguezuelos and R. Cuadrado from Spain for participating in the farm selection and/or sample taking procedures. We are also grateful to CERCA Programme/Generalitat de Catalunya.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Maternally-derived antibodies ; Porcine circovirus 2 ; Sow vaccination ; SDG 3 - Good Health and Well-being
Publicat a:	Porcine health management, Vol. 8 Núm. 1 (2022) , p. 41, ISSN 2055-5660

DOI: 10.1186/s40813-022-00284-9
PMID: 36192816

8 p, 1.2 MB

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