The added value of 18f-FDG PET/CT in the assessment of onset and steroid resistant polimyalgia rheumatica
Moya, Patricia (Institut d'Investigació Biomèdica Sant Pau)
Fernández-León, Alejandro (Institut d'Investigació Biomèdica Sant Pau)
Corica, María Emilia (Department of Rheumatology. Hospital José N. Lencinas)
Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau)
Lopez-Mora, Diego Alfonso (Institut d'Investigació Biomèdica Sant Pau)
Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau)
Corominas, Hèctor (Institut d'Investigació Biomèdica Sant Pau)

Data:	2021
Resum:	PMR is a common inflammatory rheumatic disease. Although its clinical characteristics are fully recognized, no specific test for its diagnosis has been established to date. Several studies have described a wide variety of diseases that present with polymyalgic symptoms. A 18FDG-PET/CT scan could help to deal with these differential diagnoses. The goal of our study is to describe the findings of the 18FDG-PET/CT scan in a cohort of PMR patients and to detail how the 18FDG-PET/CT scan improves accuracy when diagnosing other underlying conditions. This cross-sectional study enrolled patients with a diagnosis of PMR who underwent to a 18FDG-PET/CT scan to rule out other diagnosis. The 18FDG-PET/CT scan was performed either following clinical criteria at the onset of clinical symptoms or when the patient became PMR steroid resistant. Patients' demographic, clinical and analytical data at the moment of the 18FDG-PET/CT scan were recorded. The final diagnosis was confirmed according to clinical judgement. A total of 103 patients with PMR were included. In 49. 51% of patients, the 18FDG-PET/CT scan was ordered to study resistance to steroid therapy. The final diagnoses of patients were PMR in 70. 9% patients, large vessel vasculitis in 15. 5%, neoplasms 4. 8% and another diagnosis in the rest. The 18FDG-PET/CT scan is a very useful technique for the study of Polymyalgia Rheumatica, not only to help in the diagnostic process, but also due to its role in the identification of a variety of PMR-like patrons.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Aged ; Cross-Sectional Studies ; Drug Resistance ; Female ; Fluorodeoxyglucose F18 ; Humans ; Male ; Polymyalgia Rheumatica ; Radiopharmaceuticals ; Retrospective Studies ; Steroids
Publicat a:	PloS one, Vol. 16 Núm. 9 September (september 2021) , p. e0255131, ISSN 1932-6203

DOI: 10.1371/journal.pone.0255131
PMID: 34559822

13 p, 888.8 KB

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