Rationale and Design of the Efficacy of a Standardized Diuretic Protocol in Acute Heart Failure Study
Dauw, Jeroen (UHasselt-Hasselt University. Doctoral School for Medicine and Life Sciences. LCRC)
Lelonek, Malgorzata (Department of Noninvasive Cardiology. Medical University of Lodz)
Zegrí-Reiriz, Isabel (Institut d'Investigació Biomèdica Sant Pau)
Paredes-Paucar, Cynthia P. (Instituto Nacional de Cardiología Ignacio Chávez)
Zara, Cornelia Ancuta (Theracardia Clinic)
George, Varghese (Pushpagiri Institute of Medical Sciences)
Cobo-Marcos, M. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
Knappe, Dorit (Department of Cardiology. University Heart and Vascular Center Hamburg)
Shchekochikhin, Dimitry (Department of cardiology. sonography and functional diagnostics. First Moscow State Medical University)
Lekhakul, Annop (Wetchakarunrasm Hospital)
Klincheva, Milka (Zan Mitrev Clinic)
Frea, Simone (Città della Salute e della Scienza Hospital (Turin, Itàlia))
Miró, Oscar (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Barker, Diane (University Hospitals of North Midlands)
Borbély, Attila (Department of Cardiology. Faculty of Medicine. University of Debrecen)
Nasr, Samer (Department of Cardiology. Mount Lebanon Hospital-Balamand University Medical Center)
Doghmi, Nawal (CHU Ibn Sina. Mohammed V University (Marroc))
De la Espriella, Rafael (Hospital Clínic Universitari (València))
Singh, Jagdeep S. (The Heart Centre. Royal Infirmary of Edinburgh)
Bovolo, Virginia (Department of Cardiology. Michele e Pietro Ferrero Hospital)
Fialho, Inês (Department of Cardiology. Hospital Doutor Fernando Fonseca)
Ross, Noel T. (Kuala Lumpur General Hospital)
van den Heuvel, Mieke (Department of Cardiology. Thorax Centrum Twente. Medisch Spectrum Twente)
Benkouar, Riad (Benyoucef Benkhedda Faculty of Medicine. Mustapha Pacha Hospital. University of Algiers)
Findeisen, Hajo (Red Cross Hospital (Alemanya))
Alhaddad, Imad A. (Jordan Hospital)
Al Balbissi, Kais (Department of Cardiology. Abdali Hospital)
Barge-Caballero, Gonzalo (Instituto de Investigación Biomédica de A Coruña)
Ghazi, Azmee M. (National Heart Institute)
Bruckers, Liesbeth (I-BioStat. Data Science Institute. Hasselt University)
Martens, P. (Ziekenhuis Oost-Limburg (Genk, Bèlgica). Department of Cardiology)
Mullens, Wilfried (Hasselt University. Biomedical Research Institute)
Universitat Autònoma de Barcelona

Data:	2021
Resum:	Aims: Although acute heart failure (AHF) with volume overload is treated with loop diuretics, their dosing and type of administration are mainly based upon expert opinion. A recent position paper from the Heart Failure Association (HFA) proposed a step-wise pharmacologic diuretic strategy to increase the diuretic response and to achieve rapid decongestion. However, no study has evaluated this protocol prospectively. Methods and results: The Efficacy of a Standardized Diuretic Protocol in Acute Heart Failure (ENACT-HF) study is an international, multicentre, non-randomized, open-label, pragmatic study in AHF patients on chronic loop diuretic therapy, admitted to the hospital for intravenous loop diuretic therapy, aiming to enrol 500 patients. Inclusion criteria are as follows: at least one sign of volume overload (oedema, ascites, or pleural effusion), use ≥ 40 mg of furosemide or equivalent for.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Diuretics ; Furosemide ; Heart Failure ; Humans ; Infusions, Intravenous ; Sodium Potassium Chloride Symporter Inhibitors ; Acute heart failure ; Urinary sodium ; Decongestion ; Protocol
Publicat a:	ESC Heart Failure, Vol. 8 Núm. 6 (december 2021) , p. 4685-4692, ISSN 2055-5822

DOI: 10.1002/ehf2.13666
PMID: 34708555

8 p, 5.6 MB

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