Impact of Calorie-Restricted Cafeteria Diet and Treadmill Exercise on Sweet Taste in Diet-Induced Obese Female and Male Rats
Álvarez-Monell, Adam (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Subias-Gusils, Alex (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Mariné-Casadó, Roger (Eurecat. Centre Tecnològic de Catalunya)
Boqué, Noemí (Eurecat. Centre Tecnològic de Catalunya)
Caimari, Antoni (Eurecat. Centre Tecnològic de Catalunya)
Solanas, Montserrat (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Escorihuela, Rosa M (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)

Data:	2023
Resum:	The goal of the present study was to evaluate the sweet taste function in obese rats fed with a 30% calorie-restricted cafeteria diet (CAFR) and/or subjected to moderate treadmill exercise (12-17 m/min, 35 min, 5 days per week) for 9 weeks. A two-bottle preference test, a taste reactivity test, and a brief-access licking test were carried out when animals were aged 21 weeks; biometric and metabolic parameters were also measured along the interventions. Two separate experiments for females and males were performed. Behaviorally, CAF diet decreased sucrose intake and preference, as well as perceived palatability, in both sexes and decreased hedonic responses in males. Compared to the CAF diet, CAFR exerted a corrective effect on sweet taste variables in females by increasing sucrose intake in the preference test and licking responses, while exercise decreased sucrose intake in both sexes and licking responses in females. As expected, CAF diet increased body weight and Lee index and worsened the metabolic profile in both sexes, whereas CAFR diet ameliorated these effects mainly in females. Exercise had no noticeable effects on these parameters. We conclude that CAF diet might diminish appetitive behavior toward sucrose in both sexes, and that this effect could be partially reverted by CAFR diet in females only, while exercise might exert protective effects against overconsumption of sucrose in both sexes.
Ajuts:	Agencia Estatal de Investigación 2020-119391GB-I00 Ministerio de Ciencia e Innovación BES-2017-081939
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Energy restriction ; Physical activity ; Metabolic syndrome ; Sex differences ; Sucrose ; Wanting ; Liking
Publicat a:	Nutrients, Vol. 15 Núm. 1 (december 2022) , p. 144, ISSN 2072-6643

DOI: 10.3390/nu15010144
PMID: 36615803

21 p, 2.9 MB

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