Diagnostic workup of childhood interstitial lung disease
Nathan, Nadia (Sorbonne Université)
Griese, Matthias (University of Munich)
Michel, Katarzyna (University of Munich)
Carlens, Julia (Hannover Medical School)
Gilbert, Carlee (University of Liverpool)
Emiralioglu, Nagehan (Hacettepe University Faculty of Medicine)
Torrent-Vernetta, Alba (Hospital Universitari Vall d'Hebron)
Marczak, Honorata (Instituto de Salud Carlos III)
Willemse, Brigitte (Medical University of Warsaw)
Delestrain, Céline (Centre des Maladies Respiratoires Rares (França))
Epaud, Ralph (University Paris Est Créteil (França))
Universitat Autònoma de Barcelona

Data:	2023
Resum:	Childhood interstitial lung diseases (chILDs) are rare and heterogeneous diseases with significant morbidity and mortality. An accurate and quick aetiological diagnosis may contribute to better management and personalised treatment. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review summarises the roles of the general paediatrician, paediatric pulmonologists and expert centres in the complex diagnostic workup. Each patient's aetiological chILD diagnosis must be reached without prolonged delays in a stepwise approach from medical history, signs, symptoms, clinical tests and imaging, to advanced genetic analysis and specialised procedures including bronchoalveolar lavage and biopsy, if necessary. Finally, as medical progress is fast, the need to revisit a diagnosis of "undefined chILD" is stressed. Childhood interstitial lung diseases are rare and severe diseases. A stepwise approach to an aetiological diagnosis includes specific investigations performed in expert centres. The term "undefined chILD" must be regularly reassessed.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	European Respiratory Review, Vol. 32 (february 2023) , ISSN 1600-0617

DOI: 10.1183/16000617.0188-2022
PMID: 36813289

14 p, 704.4 KB

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