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Pàgina inicial > Articles > Articles publicats > Comparison of cerebral metabolic rate of oxygen, blood flow, and bispectral index under general anesthesia |
Data: | 2023 |
Resum: | The optical measurement of cerebral oxygen metabolism was evaluated. Compare optically derived cerebral signals to the electroencephalographic bispectral index (BIS) sensors to monitor propofol-induced anesthesia during surgery. Relative cerebral metabolic rate of oxygen () and blood flow (rCBF) were measured by time-resolved and diffuse correlation spectroscopies. Changes were tested against the relative BIS (rBIS) ones. The synchronism in the changes was also assessed by the R-Pearson correlation. In 23 measurements, optically derived signals showed significant changes in agreement with rBIS: during propofol induction, rBIS decreased by 67% [interquartile ranges (IQR) 62% to 71%], by 33% (IQR 18% to 46%), and rCBF by 28% (IQR 10% to 37%). During recovery, a significant increase was observed for rBIS (48%, IQR 38% to 55%), (29%, IQR 17% to 39%), and rCBF (30%, IQR 10% to 44%). The significance and direction of the changes subject-by-subject were tested: the coupling between the rBIS, , and rCBF was witnessed in the majority of the cases (14/18 and 12/18 for rCBF and 19/21 and 13/18 for in the initial and final part, respectively). These changes were also correlated in time (to , ). Optics can reliably monitor in such conditions. |
Ajuts: | European Commission. Horizon 2020 675332 European Commission. Horizon 2020 101016087 European Commission. Horizon 2020 101017113 European Commission. Horizon 2020 871124 Ministerio de Economía y Competitividad SEV-2015-0522 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017SGR1380 Fundació la Marató de TV3 201724.31 Fundació la Marató de TV3 201709.31 |
Drets: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
Llengua: | Anglès |
Document: | Article ; recerca ; Versió publicada |
Matèria: | Diffuse correlation spectroscopy ; Time-resolved spectroscopy ; Propofol-induced anesthesia ; Bispectral index ; Diffuse optics ; Cerebral blood flow ; Cerebral metabolic rate of oxygen ; Cerebral physiological changes ; Near-infrared spectroscopy |
Publicat a: | Neurophotonics, Vol. 10 (march 2023) , ISSN 2329-4248 |
23 p, 3.0 MB |