Rethinking subthreshold effects in regulatory chemical risk assessments
Agathokleous, Evgenios (Nanjing University of Information Science & Technology)
Barceló i Cullerés, Damià (Institut de Diagnosi Ambiental i Estudis de l'Aigua)
Aschner, Michael (Albert Einstein College of Medicine (Nova York, Estats Units d'Amèrica). Department of Molecular Pharmacology)
Antunes Azevedo, Ricardo (Universidade de São Paulo. Departamento de Genética)
Bhattacharya, Prosun (KTH Royal Institute of Technology. Department of Sustainable Development, Environmental Science and Engineering)
Costantini, David (Muséum National d'Histoire Naturelle (Paris))
Cutler, G. Christopher (Dalhousie University. Department of Plant, Food, and Environmental Sciences)
De Marco, Alessandra (Enea Agenzia Nazionale Per Le Nuove Tecnologie, L'Energia E Lo Sviluppo Economico Sostenibile)
Docea, Anca Oana (University of Medicine and Pharmacy of Craiova. Department of Toxicology)
Dórea, José G. (Universidade de Brasília. Faculdade de Ciências da Saúde)
Duke, Stephen (University of Mississippi. School of Pharmacy)
Efferth, Thomas (Johannes Gutenberg University. Department of Pharmaceutical Biology)
Fatta-Kassinos, Despo (University of Cyprus. Department of Civil and Environmental Engineering)
Fotopoulos, Vasileios (Cyprus University of Technology. Department of Agricultural Sciences, Biotechnology and Food Science)
Ginebreda, Antonio (Institut de Diagnosi Ambiental i Estudis de l'Aigua)
Guedes, Raul Narciso C. (Universidade Federal de Viçosa. Departamento de Entomologia)
Hayes, A. Wallace (University of South Florida. College of Public Health)
Iavicoli, Ivo (Università degli Studi di Napoli Federico II. Dipartimento di Sanità Pubblica)
Kalantzi, Olga-Ioanna (University of the Aegean. Department of Environment)
Koike, Takayoshi (Hokkaido University. Research Faculty of Agriculture)
Kouretas, Demetrios (University of Thessaly. Department of Biochemistry-Biotechnology)
Kumar, Manish (University of Petroleum and Energy Studies (Dehradun). School of Engineering)
Manautou, José E. (University of Connecticut. Department of Pharmaceutical Science)
Moore, Michael N. (University of Exeter Medical School)
Paoletti, Elena (Consiglio Nazionale delle Ricerche. Institute of Research on Terrestrial Ecosystems (Florència))
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Picó, Yolanda (Universitat de València. Centre d'Investigacions sobre Desertificació)
Reiter, Russel J. (University of Texas Health San Antonio. Department of Cell Systems and Anatomy)
Rezaee, Ramin (Mashhad University of Medical Sciences)
Rinklebe, Jörg (University of Wuppertal. School of Architecture and Civil Engineering)
Rocha-Santos, Teresa (University of Aveiro. Centre for Environmental and Marine Studies)
Sicard, Pierre (ARGANS)
Sonne, Christian (Aarhus University. Department of Bioscience)
Teaf, Christopher (Florida State University. Institute of Science & Public Affairs)
Tsatsakis, Aristidis (University of Crete. Medical School)
Vardavas, Alexander I. (University of Crete. Medical School)
Wang, Wenjie (Northeast Forestry University. Key Laboratory of Forest Plant Ecology)
Zeng, Eddy (Jinan University. School of Environment)
Calabrese, Edward J. (University of Massachussets. Department of Environmental Health Sciences)

Data:	2022
Resum:	A great number of dose-response studies indicate that hormesis is a common phenomenon, occurring in numerous organisms exposed to singular or combined environmental stressors, such as pharmaceuticals, heavy metals, micro/nanoplastics, organic flame retardants, pesticides, and rare earths. (1-6) While biological responses to low exposure levels are often beneficial, exposure to doses below the no-observed-adverse-effect-level (NOAEL; hereafter subthreshold doses) does not always translate to beneficial responses. (2,4).
Drets:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Cancer ; Crops ; Environmental modeling ; Impurities ; Risk assessment
Publicat a:	Environmental Science & Technology, Vol. 56, issue 26 (2022) , p. 11095-11099, ISSN 1520-5851

DOI: 10.1021/acs.est.2c02896

Postprint 14 p, 324.4 KB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > CREAF (Centre de Recerca Ecològica i d'Aplicacions Forestals)
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