Outcomes of Bariatric Surgery in Patients with Schizophrenia
Miñambres, Inka (Institut de Recerca Sant Pau)
Rubio, Miguel Angel (Universidad Complutense de Madrid)
Nicolau, Joana (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears))
Milad, Camila (Hospital Clínic i Provincial de Barcelona)
Morales, Maria José (Complexo Hospitalario Universitario de Vigo)
Bueno, Marta (Institut de Recerca Biomèdica Lleida (IRB-Lleida))
Calañas, Alfonso (Hospital Universitario Reina Sofía (Còrdova, Espanya))
Carceller-Sindreu, Mar (Institut de Recerca Sant Pau)
de Hollanda, Ana (Hospital Clínic i Provincial de Barcelona)
Universitat Autònoma de Barcelona

Data:	2024
Resum:	Background: Outcomes of bariatric surgery (BS) in patients with schizophrenia are poorly understood. We aimed to analyze the effects of BS in patients with schizophrenia (SZ) or schizoaffective disorder (SZA). Methods: This was a multicenter, retrospective case-control study in patients with SZ or SZA who had undergone BS in seven public referral hospitals in Spain. Controls without psychiatric comorbidity were selected in a 1:4 ratio. Detailed clinical and biochemical data were collected preoperatively and at 12, 24, 36, 48, and 60 months after BS. Results: Twenty patients with SZ (n = 15; 75%) or SZA (n = 5; 25%) and 80 matched controls were studied. There were no differences between patients and controls concerning the evolution of the percentage of total weight loss. The remission rate of the main comorbidities was similar between groups except for hypertension, which was lower in patients with a psychotic disorder from year 3. There were no mortalities within 30 days of surgery in either group. The psychiatric medication burden did not change during follow-up. Conclusions: BS is safe and effective in carefully selected patients with SZ. The course of the psychiatric disease does not seem to be worsened by the procedure.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Obesity ; Obesity surgery ; Schizophrenia ; Severe mental illness ; Weight loss
Publicat a:	Nutrients, Vol. 16 Núm. 15 (august 2024) , p. 2487, ISSN 2072-6643

DOI: 10.3390/nu16152487
PMID: 39125367

11 p, 634.5 KB

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