Long-term follow-up of early repolarization pattern in elite athletes
Serra-Grima, Ricard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Doñate, Maite (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Alvarez-Garcia, Jesus (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Barradas-Pires, Ana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Ferrero-Gregori, Andreu (Institut d'Investigació Biomèdica Sant Pau)
Carballeira, Lidia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Puig Reixach, Maria Teresa (Institut d'Investigació Biomèdica Sant Pau)
Rodríguez, Enrique (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Cinca, Juan (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública

Data:	2015
Resum:	BACKGROUND: Early repolarization pattern (ERP) is considered a benign variant of the electrocardiogram (ECG), more frequent in athletes. However, prospective studies suggested that ERP is associated with an increased risk of sudden cardiac death (SCD). The purpose of this study is to determine the prevalence, clinical characteristics, and long-term outcome of ERP in elite athletes during professional activity and after retirement. METHODS AND RESULTS: A cohort of 299 white elite athletes recruited between 1960 and 1999 was retrospectively analyzed. Athletes were eligible if they had participated for at least 6 consecutive months in high competition and retired for a minimum of 5 years before inclusion. Clinical data and ECG were abstracted from the clinical records using a questionnaire, and outcomes after a mean follow-up of 24 years were registered. Among the 299 athletes, 66% were men with a mean age of 20 (SD 6. 4) years. ERP was found in 31. 4% of participants, and it was located in lateral ECG leads in 57. 4% of cases, in inferior leads in 6. 4%, and in both leads in the remaining 36. 2%. After retirement, ERP still persisted in 53. 4% of athletes. Predictive factors for the persistence were: left ventricular hypertrophy signs at the baseline ECG (odds ratio [OR] 4. 35; 95% confidence interval [CI], 1. 43-13. 24; P =. 010), sinus bradycardia after retirement (OR 2. 56; 95% CI, 1. 09-5. 99; P =. 031), and presence of ERP during the sportive career (OR 20. 35; 95% CI, 8. 54-48. 51; P <. 001). After a mean follow-up of 24 years, no episodes of SCD occurred. CONCLUSIONS: A third of elite athletes presented ERP, and this persisted in 53. 4% of cases after retirement. After a long follow-up period, no difference in outcome of SCD was seen.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Athletes ; Early repolarization pattern ; Electrocardiogram ; Sudden cardiac death
Publicat a:	American Journal of Medicine, Vol. 128 Núm. 2 (january 2015) , p. 192.e1-192.e9, ISSN 1555-7162

DOI: 10.1016/j.amjmed.2014.06.017
PMID: 24979742

9 p, 744.5 KB

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
Articles > Articles de recerca
Articles > Articles publicats