Efficacy of Different Bacillus of Calmette-Guérin (BCG) Strains on Recurrence Rates among Intermediate/High-Risk Non-Muscle Invasive Bladder Cancers (NMIBCs) : Single-Arm Study Systematic Review, Cumulative and Network Meta-Analysis
Del Giudice, Francesco (Stanford University School of Medicine)
Asero, Vincenzo (Università degli Studi di Roma "La Sapienza")
Bologna, Eugenio (Università degli Studi di Roma "La Sapienza")
Scornajenghi, Carlo Maria (Università degli Studi di Roma "La Sapienza")
Carino, Dalila (Università degli Studi di Roma "La Sapienza")
Dolci, Virginia (Università degli Studi di Roma "La Sapienza")
Viscuso, Pietro (Università degli Studi di Roma "La Sapienza")
Salciccia, Stefano (Università degli Studi di Roma "La Sapienza")
Sciarra, Alessandro (Università degli Studi di Roma "La Sapienza")
D'Andrea, David (Medical University of Vienna)
Pradere, Benjamin (La Croix du Sud Hospital (Toulouse, França))
Moschini, Marco (Vita-Salute San Raffaele)
Mari, Andrea (Careggi University Hospital (Florència, Itàlia))
Albisinni, Simone (University of Rome Tor Vergata)
Krajewski, Wojciech (Wrocław Medical University)
Szydełko, Tomasz (Wrocław Medical University)
Małkiewicz, Bartosz (Wrocław Medical University)
Nowak, Łukasz (Wrocław Medical University)
Laukhtina, Ekaterina (Sechenov University)
Gallioli, Andrea (Institut d'Investigació Biomèdica Sant Pau)
Mertens, Laura S. (The Netherlands Cancer Institute (NKI) (Netherlands))
Marcq, Gautier (CNRS University of Lille)
Cimadamore, Alessia (University of Udine)
Afferi, Luca (Luzerner Kantonsspital (Suïssa))
Soria, Francesco (University of Studies of Torino)
Mori, Keiichiro (The Jikei University School of Medicine)
Tully, Karl Heinrich (Ruhr-Universität Bochum)
Pichler, Renate (Medical University of Innsbruck)
Ferro, Matteo (European Institute of Oncology IRCCS (Milà, Itàlia))
Tataru, Octavian Sabin (George Emil Palade University of Medicine)
Autorino, Riccardo (Rush University Medical Center)
Crivellaro, Simone (University of Illinois Hospital e Camp)
Crocetto, Felice (University of Naples "Federico II")
Busetto, Gian Maria (University of Foggia)
Basran, Satvir (Stanford University School of Medicine)
Eisenberg, Michael L. (Stanford University School of Medicine)
Chung, Benjamin Inbeh (Stanford University School of Medicine)
De Berardinis, Ettore (Università degli Studi di Roma "La Sapienza")
Universitat Autònoma de Barcelona

Data:	2023
Resum:	In an era of Bacillus of Calmette-Guérin (BCG) shortages, the comparative efficacy from different adjuvant intravesical BCG strains in non-muscle invasive bladder cancer (NMIBC) has not been clearly elucidated. We aim to compare, through a systematic review and meta-analysis, the cumulative BC recurrence rates and the best efficacy profile of worldwide available BCG strains over the last forty years. PubMed, Scopus, Web of Science, Embase, and Cochrane databases were searched from 1982 up to 2022. A meta-analysis of pooled BC recurrence rates was stratified for studies with ≤3-y vs.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Matèria:	BCG immunotherapy ; BCG strain ; Bladder cancer ; Network meta-analysis ; Non-muscle invasive bladder cancer ; Recurrence rate
Publicat a:	Cancers, Vol. 15 Núm. 7 (april 2023) , p. 1937, ISSN 2072-6694

DOI: 10.3390/cancers15071937
PMID: 37046598

25 p, 2.1 MB

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