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| Pàgina inicial > Articles > Articles publicats > The transition to motherhood : |
| Data: | 2023 |
| Resum: | We are witnessing a stark increase in scientific interest in the neurobiological processes associated with pregnancy and maternity. Convergent evidence suggests that around the time of labour, first-time mothers experience a specific pattern of neuroanatomical changes that are associated with maternal behaviour. Here we provide an overview of the human neurobiological adaptations of motherhood, focusing on the interplay between pregnancy-related steroid and peptide hormones, and neuroplasticity in the brain. We discuss which brain plasticity mechanisms might underlie the structural changes detected by MRI, which hormonal systems are likely to contribute to such neuroanatomical changes and how these brain mechanisms may be linked to maternal behaviour. This Review offers an overarching framework that can serve as a roadmap for future investigations. |
| Ajuts: | European Commission 883069 "la Caixa" Foundation LCF/PR/HR19/52160001 Instituto de Salud Carlos III PI22/01365 Instituto de Salud Carlos III PI18/00255 Ministerio de Ciencia e Innovación PRE2019-091422 |
| Nota: | Altres ajuts: Miguel Servet Type II research contract (CPII21/00016); National Institute of Mental Health (MH117482); National Science Foundation (2114381) |
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| Llengua: | Anglès |
| Document: | Article de revisió ; recerca ; Versió acceptada per publicar |
| Publicat a: | Nature Reviews Neuroscience, Vol. 24, Núm. 10 (October 2023) , p. 605-619, ISSN 1471-0048 |
Postprint 42 p, 1.7 MB |