Patient-reported outcome measures and surgery for Crohn's disease : systematic review
Kim, Whei Jun (Imperial College London)
Iskandarani, Mohamad (Imperial College London)
Manzo, Carlo A (Chelsea and Westminster Hospital NHS Foundation Trust)
Pellino, Gianluca (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Marti-Gallostra, Marc (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Tekkis, Paris P (The Royal Marsden NHS Foundation Trust)
Celentano, Valerio (Imperial College London)
Kontovounisios, Christos (Imperial College London)

Data:	2023
Resum:	Crohn's disease is an inflammatory bowel disease with up to 50 per cent of patients requiring surgery within 10 years of diagnosis. Patient-reported outcome measures (PROMs) are vital to monitor and assess patient health-related quality of life (HRQoL). This systematic review aims to evaluate PROMs within studies for perioperative Crohn's disease patients. Articles from MEDLINE, Embase, Emcare and CINAHL databases were searched to find studies relating to the assessment of HRQoL in perioperative Crohn's disease patients using PROMs and patient-reported experience measures (PREMs) from 1st January 2015 to 22nd October 2023. Bias was assessed using the ROBINS-I tool was used for non-randomized interventional studies and the Cochrane RoB2 tool was used for randomized trials. 1714 journal articles were filtered down to eight studies. Six studies focused on ileocaecal resection, one on perianal fistulas and one on the effects of cholecystectomy on patients with Crohn's disease. Within these articles, ten different PROM tools were identified (8 measures of HRQoL and 2 measures of functional outcome). Overall improvements in patient HRQoL pre- to postoperative for ileocaecal Crohn's disease were found in both paediatric and adult patients. Outcomes were comparable in patients in remission, with or without stoma, but were worse in patients with a stoma and active disease. There are significant variations in how PROMs are used to evaluate perioperative Crohn's disease outcomes and a need for consensus on how tools are used. Routine assessments using an internationally accepted online platform can be used to monitor patients and support areas of treatment pathways that require further support to ensure high standards of care. They also enable future statistical comparisons in quantitative reviews and meta-analyses. Crohn's disease (CD) is an inflammatory bowel disease that often requires surgical intervention, making patient-reported outcome measures (PROMs) an important tool for monitoring and assessing patient health-related quality of life (HRQoL). This systematic review evaluates the use of PROMs within surgical CD patients and is able to identify eight studies which collectively utilize eight measures of HRQoL and two measures of function. This review highlights the need for a consensus on how these tools are used and to monitor patients, support treatment pathways and enable future quantitative reviews and meta-analyses.
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Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	BJS Open, Vol. 7, Núm. 5 (September 2023) , ISSN 2474-9842

DOI: 10.1093/bjsopen/zrad098
PMID: 37882628

10 p, 236.5 KB

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