Multisocietal European consensus on the terminology, diagnosis, and management of patients with synchronous colorectal cancer and liver metastases : an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE
Siriwardena, Ajith (Manchester Royal Infirmary)
Serrablo, Alejandro (Hospital Universitario Miguel Servet (Saragossa))
Fretland, Åsmund Avdem (Oslo University Hospital (Oslo, Noruega))
Wigmore, Stephen J. (Royal Infirmary of Edinburgh)
Ramia-Angel, Jose Manuel (Hospital Universitario de Guadalajara)
Malik, Hassan Z. (Royal Liverpool University Hospital)
Stättner, Stefan (Visceral and Vascular Surgery (Salzkammergutklinikum, Austria))
Søreide, Kjetil (Bergen University Hospital)
Zmora, Oded (Shamir Medical Centre (Tel Aviv, Israel))
Meijerink, Martijn (Amsterdam University Medical Centre)
Kartalis, Nikolaos (Karolinska Institutet (Stockholm, Suècia))
Lesurtel, Mickaёl (Beaujon Hospital (Clichy, França))
Verhoef, Kees (Erasmus University Medical Centre)
Balakrishnan, Anita (Addenbrookes Hospital (Cambridge, Regne Unit))
Gruenberger, Thomas (Sigmund Freud University (Vienna, Austria))
Jonas, Eduard (Groote Schuur Hospital (Cape Town, Sudàfrica))
Devar, John (Chris Hani Baragwanath Hospital (Johannesburg, Sudàfrica))
Jamdar, Saurabh (Manchester Royal Infirmary)
Jones, Robert (Royal Liverpool University Hospital)
Hilal, Mohammad Abu (Poliambulanza Hospital (Brescia, Itàlia))
Andersson, Bodil (Skane University Hospital (Lund, Suècia))
Boudjema, Karim (Hôpital Pontchaillou(Rennes, França))
Mullamitha, Saifee (Christie Hospital (Manchester, Regne Unit))
Stassen, Laurents (Maastricht University Medical Centre (Maastricht, Països Baixos))
Dasari, Bobby V M. (Queen Elizabeth University Hospital (Birmingham, Regne Unit))
Frampton, Adam E. (Royal Surrey County Hospital (Guildford, Regne Unit))
Aldrighetti, Luca (IRCCS San Raffaele Hospital (Milan, Itàlia))
Pellino, Gianluca (Hospital Universitari Vall d'Hebron)
Buchwald, Pamela (Skane University Hospital (Lund, Suècia))
Gürses, Bengi (Koc University Medical Faculty (Istanbul, Turquia))
Wasserberg, Nir (Tel Aviv University)
Gruenberger, Birgit (Landesklinikum Wiener Neustadt (Wiener Neustadt, Austria))
Spiers, Harry V M. (Addenbrookes Hospital (Cambridge, Regne Unit))
Jarnagin, William (Memorial Sloan Kettering Cancer Centre (New York, Estats Units d'Amèrica))
Vauthey, Jean-Nicholas (MD Anderson Cancer Centre (Houston, Estats Units d'Amèrica))
Kokudo, Norihiro (National Centre for Global Health and Medicine (Tokyo, Japò))
Tejpar, Sabine (Hôpital Paul Brousse (Paris, França))
Valdivieso, Andres (Hospital Universitario de Cruces (Barakaldo, País Basc))
Adam, René

Data:	2023
Resum:	Contemporary management of patients with synchronous colorectal cancer and liver metastases is complex. The aim of this project was to provide a practical framework for care of patients with synchronous colorectal cancer and liver metastases, with a focus on terminology, diagnosis, and management. This project was a multiorganizational, multidisciplinary consensus. The consensus group produced statements which focused on terminology, diagnosis, and management. Statements were refined during an online Delphi process, and those with 70 per cent agreement or above were reviewed at a final meeting. Iterations of the report were shared by electronic mail to arrive at a final agreed document comprising 12 key statements. Synchronous liver metastases are those detected at the time of presentation of the primary tumour. The term 'early metachronous metastases' applies to those absent at presentation but detected within 12 months of diagnosis of the primary tumour, the term 'late metachronous metastases' applies to those detected after 12 months. 'Disappearing metastases' applies to lesions that are no longer detectable on MRI after systemic chemotherapy. Guidance was provided on the recommended composition of tumour boards, and clinical assessment in emergency and elective settings. The consensus focused on treatment pathways, including systemic chemotherapy, synchronous surgery, and the staged approach with either colorectal or liver-directed surgery as first step. Management of pulmonary metastases and the role of minimally invasive surgery was discussed. The recommendations of this contemporary consensus provide information of practical value to clinicians managing patients with synchronous colorectal cancer and liver metastases. This consensus provides a practical framework for the clinician treating patients with synchronous colorectal cancer and liver metastases.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	British journal of surgery, Vol. 110 (july 2023) , p. 1161-1170, ISSN 1365-2168

DOI: 10.1093/bjs/znad124
PMID: 37442562

10 p, 381.8 KB

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