Sacral nerve modulation for patients with fecal incontinence : long-term outcome and effects on sexual function
Brusciano, Luigi (University of Campania Luigi Vanvitelli (Nàpols, Itàlia))
Brillantino, Antonio (Antonio Cardarelli Hospital (Nàpols, Itàlia))
Pellino, Gianluca (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Marinello, Franco (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Baeten, Coen IM (Groene Hart Hospital (Gouda, Holanda))
Digesu, Alex (Imperial College NHS Healthcare (London, Regne Unit))
Naldini, Gabriele (Universitary Hospital of Pisa)
Gambardella, Claudio (University of Campania Luigi Vanvitelli (Nàpols, Itàlia))
Lucido, Francesco Saverio (University of Campania Luigi Vanvitelli (Nàpols, Itàlia))
Sturiale, Alessandro (Universitary Hospital of Pisa)
Gualtieri, Giorgia (University of Campania Luigi Vanvitelli (Nàpols, Itàlia))
Riss, Stefan (Medical University Vienna)
Docimo, Ludovico (University of Campania Luigi Vanvitelli (Nàpols, Itàlia))

Data:	2023
Resum:	Sacral nerve modulation has become an established treatment for fecal and urinary incontinence, and sexual disorders. The objective of this study was to evaluate the long-term outcome of sacral neuromodulation in patients with fecal or combined fecal and urinary incontinence (double incontinence), assessing its safety, efficacy, and impact on quality of life and sexual function. This was a multicentric, retrospective, cohort study including patients with fecal or double incontinence who received sacral neuromodulation at seven European centers between 2007 and 2017 and completed a 5-year follow-up. The main outcome measures included improvements of incontinence symptoms and quality of life compared with baseline, evaluated using validated tools and questionnaires at 1-, 6-, 12-, 36- and 60-month follow-up. 108 (102 women, mean age 62. 4 ± 13. 4 years) patients were recruited, of whom 88 (81. 4%) underwent definitive implantation of the pacemaker. Patients' baseline median Cleveland Clinic Incontinence Score was 15 (10-18); it decreased to 2 (1-4) and 1 (1-2) at the 12- and 36-month follow-up (p < 0. 0001), remaining stable at the 5-year follow-up. Fecal incontinence quality of life score improved significantly. All patients with sexual dysfunction (n = 48) at baseline reported symptom resolution at the 5-year follow-up. The study was limited by the retrospective design and the relatively small patient sample. Sacral nerve modulation is an effective treatment for fecal and double incontinence, achieving satisfactory long-term success rates, with resolution of concomitant sexual dysfunction.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Sacral nerve modulation ; Fecal incontinence ; Urinary incontinence ; Double incontinence ; Urgency
Publicat a:	Updates in Surgery, Vol. 75 (july 2023) , p. 1187-1195, ISSN 2038-3312

DOI: 10.1007/s13304-023-01570-z
PMID: 37442886

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