Educational interventions and contextual factors for optimising antibiotic prescription in paediatric uncomplicated acute respiratory tract infections in primary care : scoping review of reviews
Elizondo-Alzola, Usue (Institut de Recerca Sant Pau)
Rocha, Claudio (Institut de Recerca Sant Pau)
Leache, Leire (Instituto de Investigación Sanitaria de Navarra)
León-García, Montserrat (Institut de Recerca Sant Pau)
Saiz, Luis Carlos (Instituto de Investigación Sanitaria de Navarra)
Solà, Ivan (Institut de Recerca Sant Pau)
Montesinos-Guevara, Camila (Universidad UTE)
Meade, Adriana-Gabriela (Institut de Recerca Sant Pau)
Boldú, Andrea (Institut de Recerca Sant Pau)
Bolibar i Ribas, Ignasi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Niño de Guzmán, Ena Pery (Institut de Recerca Sant Pau)
Alonso-Coello, Pablo (Institut de Recerca Sant Pau)

Data:	2025
Resum:	Inappropriate antibiotic prescription in paediatric uncomplicated acute respiratory tract infections (ARTIs) in primary care (PC) settings contributes to antimicrobial resistance. We aimed (1) to identify and describe educational interventions and their components to optimise antibiotic prescription for paediatric uncomplicated ARTIs in PC, and (2) to map contextual factors that may influence antibiotic prescription and the implementation of interventions. We searched three electronic databases (Medline, CINAHL and Epistemonikos) to identify reviews on the effectiveness of educational interventions and contextual factors, for optimising antibiotic prescription (Concept) in paediatric uncomplicated ARTIs (Population) in PC (Context). We included reviews that reported explicitly the search strategy used. Two previously calibrated reviewers independently screened the literature, extracted data, and assessed the methodological limitations. We applied the "best-fit framework synthesis approach", based on the main constructs of the Consolidated Framework for Implementation Research, and coded the data deductively by groups of analysis for reviews reporting effectiveness (e. g. antibiotic or consultation rate) or by thematic synthesis for reviews reporting contextual factors (e. g. healthcare professionals' knowledge) based on a logic model. We identified 11 reviews evaluating education intervention and their characteristics, including 182 interventions with at least one educational component (educational intervention plus another type, educational or non-educational), with 136 providing information on characteristics and effectiveness. Successful interventions' characteristics were related to the kind of intervention (e. g. communication skill training), mode of delivery (e. g. face to face), and target population (e. g. parents/caregivers). From the 22 reviews on contextual factors, healthcare professionals' attitudes and perceptions, knowledge, and health system and professionals' teams' organization (inner setting), were the most frequent themes; less information was available on individuals' characteristics (parents/children) and on outer setting (e. g. policies). We identified a large number of heterogeneous educational interventions. Combining educational interventions plus another type targeting both parents/caregivers and healthcare professionals, and considering their needs and their context may improve antibiotic prescribing in children. Further research is needed on consultation rate, knowledge, attitudes, and satisfaction outcomes and contextual factors, as well as on the cost-effectiveness of the interventions. The protocol was published in OSF iRegistries in May 2021 (Elizondo-Alzola, U).
Nota:	Altres ajuts: Fundació La Marató de TV3 (295/U/2018)
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Antibiotic prescription ; Respiratory tract infections ; Children ; Paediatrics ; Primary care ; Educational interventions ; Scoping review
Publicat a:	BMC Pediatrics, Vol. 25 Núm. 1 (May 2025) , ISSN 1471-2431

DOI: 10.1186/s12887-025-05688-4
PMID: 40420306

24 p, 2.6 MB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
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