Potential adverse health effects of ingested micro-and nanoplastics on humans : lessons learned from in vivo and in vitro mammalian models
Rubio Lorente, Laura (Pontificia Universidad Católica Madre y Maestra. Departamento de Ciencias Naturales y Exactas)
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)

Títol variant:	Potential health effects of ingested micro and nanoplastics on humans : Lessons learned from in vivo and in vitro mammalian systems
Data:	2020
Descripció:	18 pàg.
Resum:	In recent years, the terms "microplastics" (MPLs) and "nanoplastics" (NPLs) have caught increasing attention and have become the focus of many studies in ecological and environmental research areas. These tiny particles, mainly derived from the degradation of plastics, pollute the marine and terrestrial ecosystems having the ability to enter into the food web. In this way, the human consumption of food contaminated with MPLSs and NPLs is unavoidable and its related effects are still unclear. In the presented work, with the aim of complementing previous reviews on this topic, new studies related to exposure, absorption, and toxicity in mammalian in vivo and in vitro studies are presented. As novel information extracted from this work, gaps, and limitations hindering the drawing of firm conclusions and the preparation of a reliable risk assessment are identified. Subsequently, recommendations for in vivo and in vitro testing methods are given in order to perform further relevant and targeted research.
Ajuts:	Generalitat de Catalunya 2017/SGR-76
Drets:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Matèria:	Nanoplastics ; Microplastics ; Toxicity ; Mammalian models ; Adverse effects ; Human health
Publicat a:	Journal of Toxicology and Environmental Health - Part B: Critical Reviews, Vol. 23, Num. 2 (2020) , p. 51-68, ISSN 1521-6950

DOI: 10.1080/10937404.2019.1700598
PMID: 31822207

36 p, 770.3 KB

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