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Critical Limb Ischemia in Nonagenarians : A Challenge of Our Times
Casajuana Urgell, Eduard (Universitat Autònoma de Barcelona)
Calsina Juscafresa, Laura (Hospital del Mar (Barcelona, Catalunya))
Nieto Fernández, Lluís (Hospital del Mar (Barcelona, Catalunya))
Romero Montaña, Lorena (Hospital del Mar (Barcelona, Catalunya))
Llort Pont, Carme (Hospital del Mar (Barcelona, Catalunya))
Clará Velasco, Alberto (Hospital del Mar (Barcelona, Catalunya))

Data: 2022
Resum: Background: As a result of the increasing life expectancy of the western population, the number of older patients with chronic limb-threatening ischemia (CLTI) seeking medical care is growing. Our objective was to describe the characteristics of a consecutive series of nonagenarian patients with CLTI and evaluate the outcomes of their management. Materials and methods: Retrospective analysis of a consecutive series of nonagenarian patients with CLTI attended at our institution between 2005 and 2019. Primary endpoints were 1-year limb salvage and survival rates. Results: A total of 171 patients were included (mean age 92. 7, 51. 5% women), of which in 59 (34. 5%) primary major amputation (n = 10) or palliative care (n = 49) was indicated at presentation because of severe dementia (n = 30, 50. 8%), knee retraction (n = 17, 28. 8%), terminal condition (n = 13, 22%) or a non-salvageable foot (n = 28, 47. 4%). In the remaining 112 (65. 5%), the need for a revascularization was further assessed finally performing A) conservative treatment/minor amputation (n = 57, 50. 9%), B) revascularization (n = 50, 44. 6%) or C) direct major amputation (n = 5, 4. 4%), with 1-year limb salvage and survival rates of 93. 1 and 57. 4%, respectively. Predictive factors for lower survival included age >92 years (HR = 1,59, p = 0. 041), hemoglobin <10. 5 mg/dL (HR 2,34, p < 0. 001), congestive heart failure (HR = 1. 65, p = 0. 036), non-severe dementia (HR 3,11, p < 0. 001) and current mobility with wheelchair (HR 1,74, p = 0. 014). Conclusion: Nearly one-third of nonagenarian patients with CLTI have a direct indication for amputation or palliative care at presentation. In the remaining, a judicious approach with conservative treatment, minor amputation or revascularization procedures yields excellent limb salvage rates. Survival is, however, the cornerstone of these patients. It can be predicted with certain clinical factors which may help decision-making.
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Llengua: Anglès
Document: Article ; recerca ; Versió acceptada per publicar
Matèria: Critical limb ischemia ; Nonagenarians ; Revascularization ; Amputation free survival
Publicat a: World Journal of Surgery, Vol. 46, Num. 11 (November 2022) , p. 2825-2831, ISSN 1432-2323

DOI: 10.1007/s00268-022-06570-5


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