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Articles 27 registres trobats  anterior11 - 20següent  anar al registre: La cerca s'ha fet en 0.00 segons. 
11.
19 p, 2.1 MB Plasma microRNA Profiling Reveals Novel Biomarkers of Epicardial Adipose Tissue : A Multidetector Computed Tomography Study / Gonzalo Calvo, David de (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Viladés Medel, David (Institut d'Investigació Biomèdica Sant Pau) ; Martínez-Camblor, Pablo (Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA) ; Vea, Àngela (Institut d'Investigació Biomèdica Sant Pau) ; Ferrero-Gregori, Andreu (Institut d'Investigació Biomèdica Sant Pau) ; Nasarre, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Bornachea, Olga (Institut d'Investigació Biomèdica Sant Pau) ; Sanchez Vega, Jesus (Institut d'Investigació Biomèdica Sant Pau) ; Leta, Rubén (Institut d'Investigació Biomèdica Sant Pau) ; Puig Grifol, Núria (Institut d'Investigació Biomèdica Sant Pau) ; Benitez, Sonia (Institut d'Investigació Biomèdica Sant Pau) ; Sanchez-Quesada, Jose Luis (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ; Carreras Costa, Francesc (Institut d'Investigació Biomèdica Sant Pau) ; Llorente-Cortés, Vicenta (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as a source of biomarkers for epicardial fat volume (EFV). [...]
2019 - 10.3390/jcm8060780
Journal of clinical medicine, Vol. 8 (june 2019)  
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12.
12 p, 975.8 KB Association of miR-21-5p, miR-122-5p, and miR-320a-3p with 90-Day Mortality in Cardiogenic Shock / Hänninen, Mikko (Minerva Foundation Institute for Medical Research (Finland)) ; Jäntti, Toni (Helsinki University Hospital (Finlàndia)) ; Tolppanen, Heli (Helsinki University Hospital (Finlàndia)) ; Segersvärd, Heli (Minerva Foundation Institute for Medical Research (Finland)) ; Tarvasmäki, Tuukka (Helsinki University Hospital (Finlàndia)) ; Lassus, Johan (Helsinki University Hospital (Finlàndia)) ; Vausort, Mélanie (Luxembourg Institute of Health) ; Devaux, Yvan (Luxembourg Institute of Health) ; Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ; Tikkanen, Ilkka (Helsinki University Hospital (Finlàndia)) ; Harjola, Veli-Pekka (Helsinki University Hospital (Finlàndia)) ; Lakkisto, Päivi (Helsinki University Hospital (Finlàndia)) ; Universitat Autònoma de Barcelona
Cardiogenic shock (CS) is a life-threatening emergency. New biomarkers are needed in order to detect patients at greater risk of adverse outcome. Our aim was to assess the characteristics of miR-21-5p, miR-122-5p, and miR-320a-3p in CS and evaluate the value of their expression levels in risk prediction. [...]
2020 - 10.3390/ijms21217925
International journal of molecular sciences, Vol. 21 (october 2020)  
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13.
9 p, 1.5 MB FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b / Coccia, Elena (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Masanas, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; López-Soriano, Joaquín (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Comella i Carnicé, Joan Xavier 1963- (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pérez-García, M. Jose (Universitat Autònoma de Barcelona. Institut de Neurociències)
Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i. [...]
2020 - 10.3389/fcell.2020.584606
Frontiers in Cell and Developmental Biology, Vol. 8 (december 2020)  
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14.
13 p, 1.2 MB Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR-127 in aged animals / Loppi, Sanna (University of Arizona) ; Korhonen, Paula (University of Eastern Finland) ; Bouvy-Liivrand, Maria (University of Eastern Finland) ; Caligola, Simone (University of Verona) ; Turunen, Tiia A. (University of Eastern Finland) ; Turunen, Mikko P. (University of Eastern Finland) ; Hernandez de Sande, Ana (University of Eastern Finland) ; Kołosowska, Natalia (University of Eastern Finland) ; Scoyni, Flavia (University of Eastern Finland) ; Rosell Novel, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lemarchant, Sighild (University of Eastern Finland) ; Dhungana, Hiramani (University of Helsinki) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Koistinaho, Jari (University of Helsinki) ; Kanninen, Katja M. (University of Eastern Finland) ; Kaikkonen, Minna U. (University of Eastern Finland) ; Giugno, Rosalba (University of Verona) ; Heinäniemi, Merja (University of Eastern Finland) ; Malm, Tarja (University of Eastern Finland) ; Universitat Autònoma de Barcelona
Ischemic stroke, the third leading cause of death in the Western world, affects mainly the elderly and is strongly associated with comorbid conditions such as atherosclerosis or diabetes, which are pathologically characterized by increased inflammation and are known to influence the outcome of stroke. [...]
2020 - 10.1111/acel.13287
Aging Cell, Vol. 20 (december 2020)  
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15.
53 p, 1.3 MB Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach / Mármol-Sánchez, Emilio (Centre de Recerca en Agrigenòmica) ; Cirera, Susanna (University of Copenhagen. Department of Veterinary and Animal Sciences (Denmark)) ; Quintanilla, Raquel (Institut de Recerca i Tecnologia Agroalimentàries) ; Pla, Albert (University of Oslo. Department of Medical Genetics (Norway)) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica)
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we designed a comprehensive pipeline (eMIRNA) for miRNA identification in the yet poorly annotated porcine genome and demonstrated the usefulness of implementing a motif search positional refinement strategy for the accurate determination of precursor miRNA boundaries. [...]
2020 - 10.1016/j.ygeno.2019.12.005
Genomics, Vol. 112, Issue 3 (May 2020) , p. 2107-2118
2 documents
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16.
11 p, 2.1 MB Interplay between ncRNAs and cellular communication : A proposal for understanding cell-specific signaling pathways / Ramón y Cajal, Santiago (Centro de Investigación Biomédica en Red de Cáncer) ; Segura, M. F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hümmer, Stefan (Centro de Investigación Biomédica en Red de Cáncer) ; Universitat Autònoma de Barcelona
Intercellular communication is essential for the development of specialized cells, tissues, and organs and is critical in a variety of diseases including cancer. Current knowledge states that different cell types communicate by ligand-receptor interactions: hormones, growth factors, and cytokines are released into the extracellular space and act on receptors, which are often expressed in a cell-type-specific manner. [...]
2019 - 10.3389/fgene.2019.00281
Frontiers in genetics, Vol. 10 Núm. APR (2019) , p. 281  
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17.
16 p, 2.0 MB Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus / Sánchez Sanuy, Ferran (Centre de Recerca en Agrigenòmica) ; Peris Peris, Cristina (Centre de Recerca en Agrigenòmica) ; Tomiyama, Shiho (University of Tokyo. Biotechnology Research Center (Japan)) ; Okada, Kazunori (University of Tokyo. Biotechnology Research Center (Japan)) ; Hsing, Yue-Ie (Academia Sinica (Taiwan). Institute of Plant and Microbial Biology) ; San Segundo, Blanca (Centre de Recerca en Agrigenòmica) ; Campo, Sonia (Centre de Recerca en Agrigenòmica)
Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level in eukaryotes. In rice, MIR7695 expression is regulated by infection with the rice blast fungus Magnaporthe oryzae with subsequent down-regulation of an alternatively spliced transcript of natural resistance-associated macrophage protein 6 (OsNramp6). [...]
2019 - 10.1186/s12870-019-2156-5
BMC plant biology, Vol. 19 (December 2019) , art. 563  
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18.
8 p, 811.3 KB African swine fever virus does not express viral microRNAs in experimentally infected pigs / Núñez-Hernández, Fernando (Institut de Recerca i Tecnologia Agroalimentàries) ; Vera Rodríguez, Gonzalo (Centre de Recerca en Agrigenòmica) ; Sánchez Bonastre, Armando (Centre de Recerca en Agrigenòmica) ; Rodriguez, Fernando (Institut de Recerca i Tecnologia Agroalimentàries) ; Núñez, J. Ignacio (Institut de Recerca i Tecnologia Agroalimentàries)
Background: African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), a re-expanding devastating and highly lethal hemorrhagic viral disease. microRNAs (miRNAs) are a new class of small non-coding RNAs that regulate gene expression post-transcriptionally. [...]
2018 - 10.1186/s12917-018-1601-2
BMC veterinary research, Vol. 14 (September 2018) , art. 268  
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19.
5 p, 173.0 KB Circulating levels of 423-5p are associated with 90 day mortality in cardiogenic shock / Jäntti, Toni (Helsinki University Hospital (Finlàndia)) ; Segersvärd, Heli (Minerva Foundation Institute for Medical Research and University of Helsinki) ; Tolppanen, Heli (Helsinki University Hospital (Finlàndia)) ; Tarvasmäki, Tuukka (Helsinki University Hospital (Finlàndia)) ; Lassus, Johan (Helsinki University Hospital (Finlàndia)) ; Devaux, Yvan (Luxembourg Institute of Health) ; Vausort, Mélanie (Luxembourg Institute of Health) ; Pulkki, Kari (Department of Clinical Chemistry, University of Eastern Finland and Eastern Finland Laboratory Centre (ISLAB)) ; Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tikkanen, Ilkka (Helsinki University Hospital (Finlàndia)) ; Lakkisto, Päivi (Helsinki University Hospital (Finlàndia)) ; Harjola, Veli-Pekka (Helsinki University Hospital (Finlàndia)) ; Universitat Autònoma de Barcelona. Departament de Medicina
The role of microRNAs has not been studied in cardiogenic shock. We examined the potential role of miR-423-5p level to predict mortality and associations of miR-423-5p with prognostic markers in cardiogenic shock. [...]
2018 - 10.1002/ehf2.12377
ESC Heart Failure, Vol. 6 (november 2018) , p. 98-102  
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20.
10 p, 957.5 KB Direct and Label-Free Quantification of Micro-RNA-181a at Attomolar Level in Complex Media Using a Nanophotonic Biosensor / Huertas, César S. (Institut Català de Nanociència i Nanotecnologia) ; Fariña, David (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Micro-RNA signatures have emerged as advantageous biomarkers for disease prediction opening the route for the development of more direct and accurate therapies. There is an urgent need for reliable tools which can offer fast, highly sensitive, and selective detection of multiple miRNAs in complex matrices as opposed to the conventional techniques. [...]
2016 - 10.1021/acssensors.6b00162
ACS Sensors, Vol. 1, Núm. 6 (June 2016) , p. 748-756  
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Articles : 27 registres trobats   anterior11 - 20següent  anar al registre:
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