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444.
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10 p, 1.7 MB |
Epidemiology of atopic dermatitis in adults : Results from an international survey
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Barbarot, Sebastien (CHU Nantes) ;
Auziere, S. (Kantar Health) ;
Gadkari, A. (Regeneron) ;
Girolomoni, G. (University of Verona) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Simpson, E.L. (Oregon Health & Science University) ;
Margolis, D.J. (University of Pennsylvania Perelman School of Medicine) ;
de Bruin-Weller, Marjolein (University Medical Center Utrecht) ;
Eckert, L. (Sanofi) ;
Universitat Autònoma de Barcelona
There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. [...]
2018 -  10.1111/all.13401
Allergy, Vol. 73 Núm. 6 (june 2018) , p. 1284-1293
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445.
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9 p, 698.5 KB |
Efficacy of bendamustine and rituximab as first salvage treatment in chronic lymphocytic leukemia and indirect comparison with ibrutinib : A GIMEMA, ERIC and UK CLL FORUM study
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Cuneo, Antonio (St. Anna University Hospital) ;
Follows, George (Cambridge University Hospitals NHS Foundation Trust (Anglaterra)) ;
Rigolin, Gian Matteo (St. Anna University Hospital) ;
Piciocchi, Alfonso (Italian Group for Adult Hematologic Diseases (GIMEMA)) ;
Tedeschi, Alessandra (Niguarda Cancer Center) ;
Trentin, Livio (University of Padua) ;
Perez, Angeles Medina (Hospital Costa del Sol (Marbella)) ;
Coscia, Marta (University of Turin) ;
Laurenti, Luca (Policlinico A. Gemelli) ;
Musuraca, Gerardo (Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST)) ;
Farina, Lucia (Fondazione IRCCS Istituto Nazionale Tumori) ;
Delgado, Alfredo Rivas (Hospital Clínic i Provincial de Barcelona) ;
Orlandi, Ester Maria (Fondazione IRCCS Policlinico San Matteo) ;
Galieni, Piero (Ospedale C. e G. Mazzoni) ;
Mauro, Francesca Romana ("Sapienza" University) ;
Visco, Carlo (San Bortolo Hospital) ;
Amendola, Angela (San Carlo Hospital) ;
Billio, Atto (Azienda Sanitaria dell'Alto Adige) ;
Marasca, Roberto (University of Modena and Reggio Emilia) ;
Chiarenza, Annalisa (Azienda Universitaria Ospedaliera Policlinico Vittorio Emanuele) ;
Meneghini, Vittorio (University Hospital) ;
Ilariucci, Fiorella (Arcispedale S. Maria Nuova) ;
Marchetti, Monia (Cardinal Massaia Hospital) ;
Molica, Stefano (Azienda Ospedaliera Pugliese Ciaccio) ;
Re, Francesca (University Hospital) ;
Gaidano, Gianluca (Università del Piemonte Orientale Amedeo Avogadro) ;
Gonzalez, Marcos (Hospital Universitari IBSAL i CIBERONC) ;
Forconi, Francesco (University Hospital National Health Service Trust) ;
Ciolli, Stefania (Careggi Hospital) ;
Cortelezzi, Agostino (University of Milan) ;
Montillo, Marco (Niguarda Cancer Center) ;
Smolej, Lukas (University Hospital) ;
Schuh, Anna (Oxford University Hospitals NHS Foundation Trust) ;
Eyre, Toby A. (Oxford University Hospitals NHS Foundation Trust) ;
Kennedy, Ben (University Hospitals of Leicester NHS Trust) ;
Bowles, Kris M. (Norwich Medical School) ;
Vignetti, Marco (Italian Group for Adult Hematologic Diseases (GIMEMA)) ;
De La Serna, Javier (Hospital 12 de Octubre (Madrid)) ;
Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ;
Foà, Robin ("Sapienza" University) ;
Ghia, Paolo (IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University) ;
Universitat Autònoma de Barcelona
We performed an observational study on the efficacy of bendamustine and rituximab (BR) as first salvage regimen in chronic lymphocytic leukemia (CLL). In an intention-to-treat analysis including 237 patients, the median progression-free survival (PFS) was 25 months. [...]
2018 - 10.3324/haematol.2018.189837
Haematologica, Vol. 103 Núm. 7 (march 2018) , p. 1209-1217
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446.
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11 p, 814.5 KB |
Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals : Examining the Necessity to Adjust for Biomarker Status in Normative Data
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Bos, Isabelle (Maastricht University) ;
Vos, Stephanie J.B. (Maastricht University) ;
Jansen, Willemijn J. (Maastricht University) ;
Vandenberghe, Rik (KU Leuven) ;
Gabel, Silvy (KU Leuven) ;
Estanga, Ainara (CITA-Alzheimer Foundation) ;
Ecay-Torres, Mirian (CITA-Alzheimer Foundation) ;
Tomassen, Jori (Vrije Universiteit Amsterdam) ;
den Braber, Anouk (Vrije Universiteit Amsterdam) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Wallin, Anders (University of Gothenburg Sahlgrenska Academy) ;
Kettunen, Petronella (University of Oxford) ;
Molinuevo, José Luis (Universitat Pompeu Fabra) ;
Rami, Lorena (Hopsital Clínic Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS)) ;
Chetelat, Gaël (Université de Caen-Normandie GIP Cyceron) ;
de la Sayette, Vincent (CHU de Caen) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Freund-Levi, Yvonne (Norrtälje Hospital Tiohundra) ;
Johannsen, Peter (University of Copenhagen) ;
Novak, Gerald P. (Janssen Pharmaceutical Research and Development) ;
Ramakers, Inez (Maastricht University) ;
Verhey, Frans R. (Maastricht University) ;
Visser, Pieter J. (Vrije Universiteit Amsterdam) ;
Universitat Autònoma de Barcelona
We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. [...]
2018 - 10.3389/fnagi.2018.00193
Frontiers in aging neuroscience, Vol. 10 (25 2018) , p. 193
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447.
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9 p, 1.5 MB |
Circulating metabolomic profile can predict dyslipidemia in HIV patients undergoing antiretroviral therapy
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Rodríguez-Gallego, Esther (Hospital Universitari Joan XXIII de Tarragona) ;
Gómez, Josep (Universitat Rovira i Virgili) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Ferrando-Martínez, Sara (National Institutes of Health (NIH)) ;
Peraire, Joaquim (Hospital Universitari Joan XXIII de Tarragona) ;
Viladés, Consuelo (Hospital Universitari Joan XXIII de Tarragona) ;
Veloso, Sergi (Hospital Universitari Joan XXIII de Tarragona) ;
López-Dupla, Miguel (Hospital Universitari Joan XXIII de Tarragona) ;
Beltrán-Debón, Raúl (Hospital Universitari Joan XXIII de Tarragona) ;
Alba, Verónica (Hospital Universitari Joan XXIII de Tarragona) ;
Vargas, Montserrat (Hospital Universitari Joan XXIII de Tarragona) ;
Castellano, Alfonso J. (Hospital Universitari Joan XXIII de Tarragona) ;
Leal, Manuel (Universidad de Sevilla) ;
Pacheco, Yolanda María (Universidad de Sevilla) ;
Ruiz-Mateos, Ezequiel (Universidad de Sevilla) ;
Gutiérrez, Félix (Hospital General de Elche y Universidad Miguel Hernández) ;
Vidal, Francesc (Hospital Universitari Joan XXIII de Tarragona) ;
Rull, Anna (Hospital Universitari Joan XXIII de Tarragona) ;
Universitat Autònoma de Barcelona
Dyslipidemia in HIV-infected patients is unique and pathophysiologically associated with host factors, HIV itself and the use of antiretroviral therapy (ART). The use of nuclear magnetic resonance spectroscopy (NMR) provides additional data to conventional lipid measurements concerning the number of lipoprotein subclasses and particle sizes. [...]
2018 - 10.1016/j.atherosclerosis.2018.04.008
Atherosclerosis, Vol. 273 (june 2018) , p. 28-36
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448.
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25 p, 635.6 KB |
CD34 + Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age >50 Years with Acute Myelogenous Leukemia and Myelodysplastic Syndrome
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Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Zhou, Qin (Memorial Sloan Kettering Cancer Center) ;
Cho, Christina (Weill Cornell Medical College) ;
Castro-Malaspina, Hugo (Weill Cornell Medical College) ;
Devlin, Sean M (Memorial Sloan Kettering Cancer Center) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Giralt, Sergio (Weill Cornell Medical College) ;
Jakubowski, Ann A. (Weill Cornell Medical College) ;
Caballero, Dolores (Hospital Universitario Salamanca (CAUSA/IBSAL)) ;
Maloy, Molly (Memorial Sloan Kettering Cancer Center) ;
Papadopoulos, Esperanza B. (Weill Cornell Medical College) ;
Piñana, José Luis (Hospital Clínic Universitari (València)) ;
Fox, Maria Laura (Hospital Universitari Vall d'Hebron) ;
Márquez-Malaver, Francisco J. (Hospital Virgen del Rocío Sevilla) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Solano, Carlos (Hospital Clínic Universitari (València)) ;
López-Corral, Lucía (Hospital Universitario Salamanca (CAUSA/IBSAL)) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Perales, Miguel-Angel (Weill Cornell Medical College) ;
Universitat Autònoma de Barcelona
Reduced-intensity conditioning (RIC) and T cell depletion (TCD) through CD34 cell selection without the use of post-transplantation immunosuppression are 2 strategies used to reduce nonrelapse mortality (NRM) in older patients after allogeneic hematopoietic cell transplantation (allo-HCT). [...]
2018 - 10.1016/j.bbmt.2017.12.804
Biology of blood and marrow transplantation, Vol. 24 Núm. 5 (may 2018) , p. 964-972
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449.
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16 p, 2.3 MB |
Cost-effectiveness of everolimus-eluting versus bare-metal stents in ST-segment elevation myocardial infarction : An analysis from the EXAMINATION randomized controlled trial
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Schur, Nadine (University of Basel) ;
Brugaletta, Salvatore (Hospital Clínic i Provincial de Barcelona) ;
Cequier, Angel (Hospital Universitari de Bellvitge) ;
Iñiguez, Andrés (Hospital do Meixoeiro) ;
Serra, Antoni (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez-Quevedo, Pilar (Hospital Universitari San Carlos) ;
Mainar, Vicente (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Campo, Gianluca (Azienda Ospedaliera Universitaria di Ferrara (Cona, Itàlia)) ;
Tespili, Maurizio (University Hospital Bolognini Seriate) ;
Heijer, Peter den (Amphia Ziekenhuis) ;
Bethencourt, Armando (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Vazquez, Nicolás (Hospital Juan Canalejo) ;
Valgimigli, Marco (University Hospital of Bern) ;
Serruys, Patrick W. (Imperial College London) ;
Ademi, Zanfina (University of Basel) ;
Schwenkglenks, Matthias (University of Basel) ;
Sabaté, Manel (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Use of everolimus-eluting stents (EES) has proven to be clinically effective and safe in patients with ST-segment elevation myocardial infarction but it remains unclear whether it is cost-effective compared to bare-metal stents (BMS) in the long-term. [...]
2018 - 10.1371/journal.pone.0201985
PloS one, Vol. 13 Núm. 8 (august 2018) , p. e0201985
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450.
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9 p, 850.8 KB |
Intermittent hypoxia is associated with high hypoxia inducible factor-1α but not high vascular endothelial growth factor cell expression in tumors of cutaneous melanoma patients
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Almendros, Isaac (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martínez-García, Miguel Ángel (Hospital Universitari i Politècnic La Fe (València)) ;
Campos-Rodríguez, Francisco (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Riveiro-Falkenbach, Erica (Hospital Universitario 12 de Octubre) ;
Rodríguez-Peralto, José L. (Hospital Universitario 12 de Octubre) ;
Nagore, Eduardo (Fundació Institut Valencià d'Oncologia) ;
Martorell-Calatayud, Antonio (Hospital de Manises (València)) ;
Blasco, Luis Hernández (Univ. Miguel Hernandez) ;
Roca, Jose Bañuls (Univ. Miguel Hernandez) ;
Vives, Eusebi Chiner (Hospital san Juan de Alicante) ;
Sánchez-de-la-Torre, Alicia (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montserrat Canal, José Ma (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Gil, Amalia (Hospital de Valme) ;
Cabriada-Nuño, Valentín (Hospital Universitario Cruces) ;
Cano-Pumarega, Irene (Hospital Universitario de Getafe) ;
Corral-Peñafiel, Jaime (Hospital Universitario S. Pedro Alcántara) ;
Diaz-Cambriles, Trinidad (Hospital 12 de Octubre (Madrid)) ;
Mediano, Olga (CIBER de enfermedades respiratorias) ;
Dalmau-Arias, Joan (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Farré, Ramón (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gozal, David (The University of Chicago) ;
Herrera, Elidia Molina (Hospital 12 de octubre) ;
García Martín, Rosa M. (Hospital 12 de octubre) ;
de Jaime, Maria Niveiro (Universidad Miguel Hernandez) ;
Moreno, Sara (Hospital Universitario Arnau de Vilanova) ;
Ilia, Ferran Barbé (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
de la Torre, Manuel Sánchez (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
de Eusebio, Esther (Hospital Universitario de Guadalajara) ;
Landete, Pedro (Instituto de Investigación Hospital Universitario de la Princesa) ;
Gordon, Manuel Moragón (Hospital Universitario) ;
Arias, Eva (Hospital 12 de Octubre (Madrid)) ;
Masa, Fernando (Hospital Universitario S. Pedro Alcántara) ;
Herrada, Carlos González (Hospital Universitario de Getafe) ;
Carrera, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Muñoz Ferrer, Aida (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boada, Aram (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fortuna Gutiérrez, Ana Mª (Institut d'Investigació Biomèdica Sant Pau) ;
Mayos, Mercè (Institut d'Investigació Biomèdica Sant Pau) ;
García, Jesús Gardeazabal (Hospital Universitario Cruces) ;
Universitat Autònoma de Barcelona
Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in the tumor and altered immune functions via intermittent hypoxia (IH). [...]
2018 - 10.3389/fneur.2018.00272
Frontiers in neurology, Vol. 9 Núm. APR (26 2018) , p. 272
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451.
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15 p, 797.9 KB |
The GRADE Evidence to Decision (EtD) framework for health system and public health decisions
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Moberg, Jenny (Norwegian Institute of Public Health) ;
Oxman, Andrew D. (Norwegian Institute of Public Health) ;
Rosenbaum, Sarah (Norwegian Institute of Public Health) ;
Schünemann, Holger J. (McMaster University (Canadà)) ;
Guyatt, Gordon (McMaster University (Canadà)) ;
Flottorp, Signe (Norwegian Institute of Public Health) ;
Glenton, Claire (Norwegian Institute of Public Health) ;
Lewin, Simon (South African Medical Research Council) ;
Morelli, Angela (Norwegian Institute of Public Health) ;
Rada, Gabriel (Pontificia Universidad Católica de Chile) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
To describe a framework for people making and using evidence-informed health system and public health recommendations and decisions. We developed the GRADE Evidence to Decision (EtD) framework for health system and public health decisions as part of the DECIDE project, in which we simultaneously developed frameworks for these and other types of healthcare decisions, including clinical recommendations, coverage decisions and decisions about diagnostic tests. [...]
2018 - 10.1186/s12961-018-0320-2
Health Research Policy and Systems, Vol. 16 Núm. 1 (29 2018) , p. 45
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452.
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8 p, 667.2 KB |
Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia
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Philtjens, Stéphanie (University of Antwerp) ;
Van Mossevelde, Sara (Antwerp University Hospital (UZA)) ;
Van der Zee, Julie (University of Antwerp) ;
Wauters, Eline (University of Antwerp) ;
Dillen, Lubina (University of Antwerp) ;
Vandenbulcke, Mathieu (University Hospitals Leuven (Bèlgica)) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Ivanoiu, Adrian (Université Catholique de Louvain) ;
Sieben, Anne (Universitair Ziekenhuis Gent) ;
Willems, Christiana (Jessa Hospital) ;
Benussi, Luisa (Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Ghidoni, Roberta (Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Binetti, Giuliano (Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Borroni, Barbara (University of Brescia) ;
Padovani, Alessandro (University of Brescia) ;
Pastor, Pau (Instituto de Salud Carlos III) ;
Diez-Fairen, Monica (Instituto de Salud Carlos III) ;
Aguilar, Miquel (Instituto de Salud Carlos III) ;
de Mendonça, Alexandre (University of Lisbon) ;
Miltenberger-Miltényi, Gabriel (University of Lisbon) ;
Hernández, Isabel (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ;
Boada, M. (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ;
Ruiz, A. (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ;
Nacmias, B. (University of Florence) ;
Sorbi, S. (IRCCS Don Gnocchi) ;
Almeida, M.Rosario (University of Coimbra) ;
Santana, Isabel (University of Coimbra) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Frisoni, Giovanni B. (IRCCS Fatebenefratelli) ;
Sanchez-Valle, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Llado Plarrumani, Albert (Hospital Clínic i Provincial de Barcelona) ;
Gómez-Tortosa, Estrella (Hospital Universitario Fundación Jiménez Díaz) ;
Gelpi, Ellen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Van den Broeck, Marleen (University of Antwerp) ;
Peeters, Karin (University of Antwerp) ;
Cras, Patrick (Antwerp University Hospital (UZA)) ;
De Deyn, Peter P. (Middelheim and Hoge Beuken) ;
Engelborghs, Sebastiaan (Middelheim and Hoge Beuken) ;
Cruts, Marc (University of Antwerp) ;
Van Broeckhoven, Christine (University of Antwerp) ;
Universitat Autònoma de Barcelona
We investigated the genetic role of sortilin (SORT1) in frontotemporal dementia (FTD). SORT1 is the neuronal receptor for granulin, encoded by the progranulin gene (GRN), a major causal gene for inherited FTD. [...]
2018 - 10.1016/j.neurobiolaging.2018.02.011
Neurobiology of Aging, Vol. 66 (june 2018) , p. 181.e3-181.e10
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453.
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7 p, 715.4 KB |
Safety and efficacy of self-administered inhaled loxapine (ADASUVE) in agitated patients outside the hospital setting : Protocol for a phase IV, single-arm, open-label trial
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Gil, Emilio (Ferrer Internacional. S.A.) ;
Garcia-Alonso, Fernando (Ferrer Internacional. S.A.) ;
Boldeanu, Anca (Ferrer Internacional. S.A.) ;
Baleeiro Teixeira, Thaïs (Ferrer Internacional. S.A.) ;
Tordera, Vicente (Hospital Lluís Alcanyis) ;
Viciedo, Ramón Palmer (Hospital Provincial de Castelló) ;
Salgado Serrano, Dr Purificación (Hospital del Mar (Barcelona, Catalunya)) ;
Domingo Ribas, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Corripio, Iluminada (Institut d'Investigació Biomèdica Sant Pau) ;
Montes, José Manuel (Hospital Universitario Ramón y Cajal (Madrid)) ;
Lauffer, Javier Correas (Hospital Univ de Henares) ;
Murugarrem, Salvador Ruiz (Hospital Príncipe de Asturias) ;
García, Santiago Ovejero (Hospital Universitario Fundación Jiménez Díaz) ;
Mora, Fernando (Hospital Universitario Infanta Leonor) ;
López, Presentación Ataz (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Navas, Andrés Fontalba (Hospital la Inmaculada) ;
Pinto, Ana Mª González (Hospital Santiago Apóstol) ;
Martínez, Ricardo (Hospital Virgen Del Mirón) ;
Castrillo, César García (Complejo Hospitalario de Jaen) ;
Toledo, Francisco (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
González, Emilio (Hermanas Hospitalarias Sociosanitario Palencia) ;
Franco Martín, Manuel (Complejo Asistencial Zamora) ;
Drasovean, Nicolae Virgil (Spitalul de Psihiatrie 'Elisabeta Doamna' Galati) ;
Dahl, Nils Hâvard (Helse Nord-Trøndelag HV Sykehuset Levanger) ;
Skagen, Bo (Spesialistesenteret På Straume-Helsesenteret) ;
Zilles, David (Klinik Für Psychiatrie und Psychotherapie der Universitätsmedizin Göttingen) ;
Zwanzger, Peter (Allgemeinpsychiatrie und Psychosomatik) ;
Juckel, Georg (LWL-Universitätsklinikum Bochum der Ruhr-Universität Bochum) ;
Kahl, Kai G. (Medizinische Hochschule Hannover) ;
Messer, Thomas (Fachklinik Für Psychiatrie) ;
Kasper, Siegfried (Medizinische Universität Wien Universitätsklinik Für Psychiatrie und Psychotherapie) ;
Universitat Autònoma de Barcelona
There is a need for fast-acting, non-injection antiagitation treatments that are well tolerated and can be used outside of healthcare facilities. In phase II/III trials, an inhaled formulation of loxapine (ADASUVE®), a well-established, first-generation antipsychotic agent, provided rapid control of mild to moderate agitation in the hospital setting. [...]
2018 - 10.1136/bmjopen-2017-020242
BMJ open, Vol. 8 Núm. 10 (january 2018) , p. e020242
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