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555.
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8 p, 594.7 KB |
The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes : Achieving HbA1c targets with basal insulin in a real-world setting
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Meneghini, Luigi F. (Parkland Health & Hospital System) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Orsi, Emanuela (Fondazione Ca' Granda IRCCS) ;
Lalic, Nebojsa M. (University of Belgrade) ;
Cali, Anna M.G. (Sanofi) ;
Westerbacka, Jukka (Sanofi) ;
Stella, Peter (Sanofi) ;
Candelas, Christophe (Sanofi) ;
Pilorget, Valerie (Sanofi) ;
Perfetti, Riccardo (Sanofi) ;
Khunti, Kamlesh (University of Leicester) ;
Universitat Autònoma de Barcelona
To describe in a real-world setting the achievement of physician-selected individualized HbA1c targets in individuals with type 2 diabetes, newly or recently initiated with basal insulin, and the association of hypoglycaemia with target achievement. [...]
2019 -  10.1111/dom.13673
Diabetes, Obesity and Metabolism, Vol. 21 Núm. 6 (june 2019) , p. 1429-1436
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556.
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9 p, 1012.4 KB |
Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity : A cross-sectional analysis from the AB255 Study
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Pérez-Grijalba, Virginia (Araclon Biotech S.L.) ;
Arbizu, Javier (Clínica Universidad de Navarra) ;
Romero, Judith (Araclon Biotech S.L.) ;
Prieto, Elena (Clínica Universidad de Navarra) ;
Pesini, Pedro (Araclon Biotech S.L.) ;
Sarasa, Leticia (Araclon Biotech S.L.) ;
Guillen, Fernando (Clínica Universidad de Navarra) ;
Monleón, Inmaculada (Araclon Biotech S.L.) ;
San-José, Itziar (Araclon Biotech S.L.) ;
Martínez-Lage, Pablo (Fundación CITA-Alzheimer) ;
Munuera, Josep (Institut de Recerca Sant Joan de Déu) ;
Hernández, Isabel (Instituto de Salud Carlos III) ;
Buendía, Mar (Universitat Internacional de Catalunya) ;
Sotolongo-Grau, Oscar (Universitat Internacional de Catalunya) ;
Alegret, Montserrat (Instituto de Salud Carlos III) ;
Ruiz, Agustín (Instituto de Salud Carlos III) ;
Tárraga, Lluís (Instituto de Salud Carlos III) ;
Boada, Mercè (Instituto de Salud Carlos III) ;
Sarasa, Manuel (Araclon Biotech S.L.) ;
Goñi Imízcoz, Miguel (Hospital Divino Vallés (Burgos)) ;
Pujadas, Francesc ;
Villarejo, Alberto ;
Frank, Ana ;
Peña-Casanova, Jordi ;
Fernández, Manuel ;
Piñol, Gerard ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Gil, Pedro ;
Pascual, Luis F. ;
Aguilar Barberà, Miquel ;
Frisoni, Giovanni B. ;
Matias-Guiu, Jorge ;
Andreasen, Niels ;
Antúnez, Carmen ;
Universitat Autònoma de Barcelona
To facilitate population screening and clinical trials of disease-modifying therapies for Alzheimer's disease, supportive biomarker information is necessary. This study was aimed to investigate the association of plasma amyloid-beta (Aβ) levels with the presence of pathological accumulation of Aβ in the brain measured by amyloid-PET. [...]
2019 - 10.1186/s13195-019-0549-1
Alzheimer's research & therapy, Vol. 11 Núm. 1 (january 2019) , p. 96
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557.
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12 p, 2.4 MB |
Interim Results from the IMPACT Study : Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers
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Page, Elizabeth C. (Institute of Cancer Research) ;
Bancroft, Elizabeth K. (Royal Marsden NHS Foundation Trust) ;
Brook, Mark N. (Institute of Cancer Research) ;
Assel, Melissa (Memorial Sloan Kettering Cancer Center) ;
Hassan Al Battat, Mona (Lund University) ;
Thomas, Sarah (Royal Marsden NHS Foundation Trust) ;
Taylor, Natalie (Royal Marsden NHS Foundation Trust) ;
Chamberlain, Anthony (Institute of Cancer Research) ;
Pope, Jennifer (Institute of Cancer Research) ;
Raghallaigh, Holly Ni (Institute of Cancer Research) ;
Evans, D.Gareth (Central Manchester University Hospitals NHS Foundation Trust) ;
Rothwell, Jeanette (Central Manchester University Hospitals NHS Foundation Trust) ;
Maehle, Lovise (Oslo University Hospital (Oslo, Noruega)) ;
Grindedal, Eli Marie (Oslo University Hospital (Oslo, Noruega)) ;
James, Paul (The Royal Melbourne Hospital) ;
Mascarenhas, Lyon (Peter MacCallum Cancer Centre) ;
McKinley, Joanne (Peter MacCallum Cancer Centre) ;
Side, Lucy (Princess Anne Hospital) ;
Thomas, Tessy (Princess Anne Hospital) ;
van Asperen, Christi (Leiden University Medical Center) ;
Vasen, Hans (The Foundation for the Detection of Hereditary Cancer) ;
Kiemeney, Lambertus A. (Radboud University Medical Center) ;
Ringelberg, Janneke (The Foundation for the Detection of Hereditary Cancer) ;
Jensen, Thomas Dyrso. (Vejle Hospital) ;
Osther, Palle J.S. (Vejle Hospital) ;
Helfand, Brian T. (NorthShore University HealthSystem) ;
Genova, Elena (NorthShore University HealthSystem) ;
Oldenburg, Rogier A. (Erasmus University Medical Center) ;
Cybulski, Cezary (Pomeranian Medical University in Szczecin) ;
Wokolorczyk, Dominika (Pomeranian Medical University in Szczecin) ;
Ong, Kai-Ren (Birmingham Women's Hospital) ;
Huber, Camilla (Birmingham Women's Hospital) ;
Lam, Jimmy (Bedford Park) ;
Taylor, Louise (Daw Park) ;
Salinas, Monica (Hospital Universitari de Bellvitge) ;
Feliubadaló, Lidia (Hospital Universitari de Bellvitge) ;
Oosterwijk, Jan C. (University of Groningen) ;
van Zelst-Stams, Wendy (Radboud University Medical Center) ;
Cook, Jackie (Sheffield Children's Hospital (Sheffield, Regne Unit)) ;
Rosario, Derek J. (Royal Hallamshire Hospital) ;
Domchek, Susan (Basser Research Center. University of Pennsylvania) ;
Powers, Jacquelyn (University of Pennsylvania) ;
Buys, Saundra (University of Utah) ;
O'Toole, Karen (University of Utah) ;
Ausems, Margreet G. E. M (University Medical Centre) ;
Schmutzler, Rita K. (University Hospital Cologne) ;
Rhiem, Kerstin (University Hospital Cologne) ;
Izatt, Louise (Guy's and St Thomas' NHS Foundation Trust) ;
Tripathi, Vishakha (Guy's and St Thomas' NHS Foundation Trust) ;
Teixeira, Manuel R. (Porto University) ;
Cardoso, Marta (Portuguese Oncology Institute (IPO Porto)) ;
Foulkes, William D. (McGill University, Departments of Human Genetics and Oncology) ;
Aprikian, Armen (Research Institute of McGill University Health Centre) ;
van Randeraad, Heleen (The Foundation for the Detection of Hereditary Cancer) ;
Davidson, Rosemarie (Queen Elizabeth University Hospital) ;
Longmuir, Mark (Queen Elizabeth University Hospital) ;
Ruijs, Marielle W.G. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Helderman van den Enden, Apollonia T.J.M. (Maastricht University Medical Center) ;
Adank, Muriel (Amsterdam UMC) ;
Williams, Rachel (Prince of Wales Hospital (Australia)) ;
Andrews, Lesley (Prince of Wales Hospital (Australia)) ;
Murphy, Declan G. (Peter MacCallum Cancer Centre) ;
Halliday, Dorothy (Oxford Centre for Genomic Medicine) ;
Walker, Lisa (Oxford Centre for Genomic Medicine) ;
Liljegren, Annelie (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Carlsson, Stefan (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Azzabi, Ashraf (Newcastle upon Tyne Hospitals) ;
Jobson, Irene (Newcastle upon Tyne Hospitals) ;
Morton, Catherine (The Royal Melbourne Hospital) ;
Shackleton, Kylie (The Royal Melbourne Hospital) ;
Snape, Katie (St George's Hospital) ;
Hanson, Helen (St George's Hospital) ;
Harris, Marion (Monash Health) ;
Tischkowitz, Marc (University of Cambridge) ;
Taylor, Amy (Cambridge University Hospitals NHS Trust) ;
Kirk, Judy (Sydney Medical School) ;
Susman, Rachel (Royal Brisbane & Women's Hospital) ;
Chen-Shtoyerman, Rakefet (Kaplan Medical Center) ;
Spigelman, Allan (The Kinghorn Cancer Centre. St Vincent's Hospital) ;
Pachter, Nicholas (University of Western Australia) ;
Ahmed, Munaza (NE Thames Regional Genetics Service) ;
Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Zgajnar, Janez (Institute of Oncology) ;
Brewer, Carole (Royal Devon and Exeter Hospital) ;
Gadea, Neus (Hospital Universitari Vall d'Hebron) ;
Brady, Angela F. (London North West University Healthcare NHS Trust) ;
van Os, Theo (Academic Medical Center) ;
Gallagher, David (St James's Hospital) ;
Johannsson, Oskar (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Donaldson, Alan (St Michael's Hospital) ;
Barwell, Julian (University Hospitals Leicester) ;
Nicolai, Nicola (Istituto Nazionale dei Tumori (Milà, Itàlia)) ;
Friedman, Eitan (Chaim Shema Medical Center) ;
Obeid, Elias (Fox Chase Cancer Center) ;
Greenhalgh, Lynn (Liverpool Women's Hospital) ;
Murthy, Vedana (Tata Memorial Centre) ;
Copakova, Lucia (National Cancer Institute) ;
Saya, Sibel (Institute of Cancer Research) ;
McGrath, John (University of Exeter Medical School) ;
Cooke, Peter (New Cross Hospital) ;
Rønlund, Karina (Vejle Hospital) ;
Richardson, Kate (Peter MacCallum Cancer Centre) ;
Henderson, Alex (West Cumberland Infirmary) ;
Teo, Soo H. (Subang Jaya Medical Centre) ;
Arun, Banu (The University of Texas) ;
Kast, Karin (Technische Universität Dresden) ;
Dias, Alexander (Instituto Nacional de Cancer Jose de Alencar Gomes da Silva (INCA)) ;
Aaronson, Neil K (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Ardern-Jones, Audrey (Royal Marsden NHS Foundation Trust) ;
Bangma, Chris H. (Erasmus University Medical Center) ;
Castro, Elena (Centro Nacional de Investigaciones Oncológicas) ;
Dearnaley, David (The Institute of Cancer Research. Royal Marsden NHS Foundation Trust (Londres, Regne Unit)) ;
Eccles, Diana M. (The University of Southampton Medical School) ;
Tricker, Karen (Central Manchester University Hospitals NHS Foundation Trust) ;
Eyfjord, Jorunn (University of Iceland) ;
Falconer, Alison (Imperial College Healthcare NHS Trust) ;
Foster, Christopher (HCA Pathology Laboratories) ;
Gronberg, Henrik (University Hospital) ;
Hamdy, Freddie C. (University of Oxford) ;
Stefansdottir, Vigdis (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Khoo, Vincent (The University of Melbourne) ;
Lindeman, Geoffrey J. (The Walter and Eliza Hall Institute of Medical Research) ;
Lubinski, Jan (Pomeranian Medical University in Szczecin) ;
Axcrona, Karol (Akershus University Hospital) ;
Mikropoulos, Christos (Medway Hospital) ;
Mitra, Anita (University College London Hospitals NHS Foundation Trust) ;
Moynihan, Clare (Institute of Cancer Research) ;
Rennert, Gadi (Carmel Medical Center) ;
Suri, Mohnish (Nottingham City Hospital) ;
Wilson, Penny (Innovate UK. Polaris House) ;
Dudderidge, Tim (University Hospital Southampton) ;
Offman, Judith (King's College London) ;
Kote-Jarai, Zsofia (Institute of Cancer Research) ;
Vickers, Andrew (Memorial Sloan Kettering Cancer Center) ;
Lilja, Hans (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ;
Eeles, Rosalind A. (Royal Marsden NHS Foundation Trust) ;
Universitat Autònoma de Barcelona
Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2 mutations. [...]
2019 - 10.1016/j.eururo.2019.08.019
European Urology, Vol. 76 Núm. 6 (december 2019) , p. 831-842
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558.
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9 p, 1.7 MB |
A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia
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Onecha, Esther (Centro Nacional de Investigaciones Oncológicas) ;
Linares, Maria (Centro Nacional de Investigaciones Oncológicas) ;
Rapado, Inmaculada (Centro de Investigación Biomédica en Red de Cáncer) ;
Ruiz-Heredia, Yanira (Centro Nacional de Investigaciones Oncológicas) ;
Martinez-Sanchez, Pilar (Hospital 12 de Octubre (Madrid)) ;
Cedena, Teresa (Centro Nacional de Investigaciones Oncológicas) ;
Pratcorona, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Oteyza, Jaime Perez (Hospital Universitario HM Sanchinarro (Madrid)) ;
Herrera, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Barragán, Eva (Hospital Universitari i Politècnic La Fe (València)) ;
Montesinos, Pau (Hospital Universitari i Politècnic La Fe (València)) ;
Vela, Jose Antonio Garcia (Hospital Universitario de Getafe (Madrid)) ;
Magro, Elena (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Anguita, Eduardo (Hospital Clínico San Carlos (Madrid)) ;
Figuera, Angela (Hospital Universitario de la Princesa (Madrid)) ;
Riaza, Rosalia (Hospital Universitario Severo Ochoa) ;
Martinez-Barranco, Pilar (Hospital Universitario Fundación Alcorcón) ;
Sanchez-Vega, Beatriz (Centro Nacional de Investigaciones Oncológicas) ;
Nomdedeu, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Gallardo, Miguel (Centro Nacional de Investigaciones Oncológicas) ;
Martinez-Lopez, Joaquin (Centro Nacional de Investigaciones Oncológicas) ;
Ayala, Rosa (Centro Nacional de Investigaciones Oncológicas) ;
Universitat Autònoma de Barcelona
A high proportion of patients with acute myeloid leukemia who achieve minimal residual disease negative status ultimately relapse because a fraction of pathological clones remains undetected by standard methods. [...]
2019 - 10.3324/haematol.2018.194712
Haematologica, Vol. 104 Núm. 2 (31 2019) , p. 288-296
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559.
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15 p, 897.4 KB |
Risk factors associated with severe outcomes in adult hospitalized patients according to influenza type and subtype
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Martínez, Ana (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Soldevila, Núria (Universitat de Barcelona) ;
Romero-Tamarit, Arantxa (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Torner, Núria (Universitat de Barcelona) ;
Godoy, Pere (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Rius i Gibert, Maria Cristina (Agència de Salut Pública de Barcelona) ;
Jané, Mireia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Domínguez, Ángela (Universitat de Barcelona) ;
Marcos, M.A. (Hospital Clínic i Provincial de Barcelona) ;
Mosquera, Maria del Mar (Hospital Clínic i Provincial de Barcelona) ;
Vilella, A. (Hospital Clínic i Provincial de Barcelona) ;
Antón, A. (Hospital Universitari Vall d'Hebron) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Navarro-Rubio, G. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Seasonal influenza is a cause of hospitalization, especially in people with underlying disease or extreme age, and its severity may differ depending on the types and subtypes of circulating viruses. We investigated the factors associated with ICU admission or death in hospitalized patients with severe laboratory-confirmed influenza according to the viral type and subtype. [...]
2019 - 10.1371/journal.pone.0210353
PloS one, Vol. 14 Núm. 1 (january 2019) , p. e0210353
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560.
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11 p, 1.9 MB |
Migrated T lymphocytes into malignant pleural effusions : an indicator of good prognosis in lung adenocarcinoma patients
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Nieto, Juan C. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Zamora, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Porcel, José M. (Hospital Universitari Arnau de Vilanova) ;
Mulet Gual, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Pajares Ruiz, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz-Fernandez, Ana M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Calvo, Nuria (Institut d'Investigació Biomèdica Sant Pau) ;
Espinosa, Iñigo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Pascual-García, Mónica (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bielsa, Silvia (Hospital Universitari Arnau de Vilanova) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The presence of leukocyte subpopulations in malignant pleural effusions (MPEs) can have a different impact on tumor cell proliferation and vascular leakiness, their analysis can help to understand the metastatic microenvironment. [...]
2019 - 10.1038/s41598-018-35840-3
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 2996
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561.
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19 p, 824.2 KB |
Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections in Leukemia (ECIL)
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Maschmeyer, Georg (Klinikum Ernst von Bergmann) ;
De Greef, Julien (Henri Mondor Teaching Hospital) ;
Mellinghoff, Sibylle C. (University of Cologne) ;
Nosari, Annamaria (ASST Grande Ospedale Metropolitano Niguarda) ;
Thiebaut-Bertrand, Anne (Université Grenoble Alpes) ;
Bergeron, Anne (APHP Saint-Louis Hospital) ;
Franquet, Tomas (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Blijlevens, Nicole M.A. (Radboud University Medical Centre) ;
Maertens, Johan A. (University of Leuven) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
A multitude of new agents for the treatment of hematologic malignancies has been introduced over the past decade. Hematologists, infectious disease specialists, stem cell transplant experts, pulmonologists and radiologists have met within the framework of the European Conference on Infections in Leukemia (ECIL) to provide a critical state-of-the-art on infectious complications associated with immunotherapeutic and molecular targeted agents used in clinical routine. [...]
2019 - 10.1038/s41375-019-0388-x
Leukemia, Vol. 33 Núm. 4 (january 2019) , p. 844-862
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562.
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563.
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10 p, 1.6 MB |
Neuroprotection mediated by cystatin C-loaded extracellular vesicles
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Pérez-González, Rocío (Institut d'Investigació Biomèdica Sant Pau) ;
Sahoo, Susmita (Icahn School of Medicine at Mount Sinai) ;
Gauthier, Sebastien A. (Nathan S. Kline Institute) ;
Kim, Yohan (NYU Langone Medical Center) ;
Li, Meihua (Nathan S. Kline Institute) ;
Kumar, Asok (Nathan S. Kline Institute) ;
Pawlik, Monika (Nathan S. Kline Institute) ;
Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Ghidoni, Roberta (IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Levy, Efrat (Neuroscience Institute) ;
Universitat Autònoma de Barcelona
Cystatin C (CysC) is implicated in neuroprotection and repair in the nervous system in response to diverse neurotoxic conditions. In addition to being secreted from cells in a soluble form, CysC is released by cells in association with extracellular vesicles (EVs), including exosomes. [...]
2019 - 10.1038/s41598-019-47524-7
Scientific reports, Vol. 9 Núm. 1 (31 2019) , p. 11104
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564.
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