Articles

Articles 30 records found  previous11 - 20next  jump to record: Search took 0.02 seconds. 
11.
16 p, 839.7 KB Natural Selection in the Great Apes / Cagan, Alexander (Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany) ; Theunert, Christoph (University of California. Department of Integrative Biology,) ; Laayouni, Hafid (Universitat Autonòma de Barcelona. Departament de Genètica i de Microbiologia) ; Santpere, Gabriel (Yale University School of Medicine. Department of Neuroscience) ; Pybus, Marc (Universitat Pompeu Fabra. Departament de Ciencies Experimentals i de la Salut, Institut de Biologia Evolutiva) ; Casals, Ferran (Universitat Pompeu Fabra. Genomics Core Facility, Departament de Ciencies Experimentals i de la Salut) ; Prüfer, Kay (Max Planck Institute for Evolutionary Anthropology. Department of Evolutionary Genetics) ; Navarro, Arcadi (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Marquès i Bonet, Tomàs, 1975- (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Bertranpetit, Jaume (University of Cambridge. Department of Archaeology and Anthropology, Leverhulme Centre for Human Evolutionary Studies) ; Andrés, Aida M. (ax Planck Institute for Evolutionary Anthropology. Department of Evolutionary Genetics)
Natural selection is crucial for the adaptation of populations to their environments. Here, we present the first global study of natural selection in the Hominidae (humans and great apes) based on genome-wide information from population samples representing all extant species (including most subspecies). [...]
2016 - 10.1093/molbev/msw215
Molecular biology and evolution, Vol. 33, Núm. 12 (desembre 2016) , p. 3268-3283  
12.
13 p, 5.2 MB The Verrucomicrobia LexA-Binding Motif : Insights into the Evolutionary Dynamics of the SOS Response / Erill, Ivan (University of Maryland Baltimore County. Erill Lab, Department of Biological Sciences) ; Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kiliç, Sefa (University of Maryland Baltimore County. Erill Lab, Department of Biological Sciences) ; Barbé García, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. In contrast to other regulatory systems, the composition of the SOS genetic network and the binding motif of its transcriptional repressor, LexA, have been shown to vary greatly across bacterial clades, making it an ideal system to study the co-evolution of transcription factors and their regulons. [...]
2016 - 10.3389/fmolb.2016.00033
Frontiers in Molecular Biosciences, Vol. 3 (july 2016) , art. 33  
13.
12 p, 1.0 MB Genome sequence of the olive tree, Olea europaea / Cruz, Fernando (Universitat Pompeu Fabra) ; Julca, Irene (Universitat Autònoma de Barcelona) ; Gómez-Garrido, Jèssica (Universitat Pompeu Fabra) ; Loska, Damian (The Barcelona Institute of Science and Technology) ; Marcet-Houben, Marina (The Barcelona Institute of Science and Technology) ; Cano, Emilio (Consejo Superior de Investigaciones Científicas) ; Galán, Beatriz (Consejo Superior de Investigaciones Científicas) ; Frias, Leonor (Universitat Pompeu Fabra) ; Ribeca, Paolo (Universitat Pompeu Fabra) ; Derdak, Sophia (Universitat Pompeu Fabra) ; Gut, Marta (Universitat Pompeu Fabra) ; Sánchez Fernández, Manuel (Grupo Santander) ; García, José Luis (Consejo Superior de Investigaciones Científicas) ; Gut, Ivo (Universitat Pompeu Fabra) ; Vargas, Pablo (Vargas Gómez) (Royal Botanical Garden of Madrid) ; Alioto, Tyler (Centre Nacional d'Anàlisi Genòmica) ; Gabaldón, Toni (CRG-Centre for Genomic Regulation)
The Mediterranean olive tree (Olea europaea subsp. europaea) was one of the first trees to be domesticated and is currently of major agricultural importance in the Mediterranean region as the source of olive oil. [...]
2016 - 10.1186/s13742-016-0134-5
GigaScience, Vol. 5, Issue 1 (December 2016) , art. 29  
14.
10 p, 479.1 KB Contrasting Genomic Diversity in Two Closely Related Postharvest Pathogens : Penicillium digitatum and Penicillium expansum / Julca, Irene (Centre de Regulació Genòmica (CGR)) ; Droby, Samir (Department of Postharvest Science. ARO. The Volcani Center. Israel) ; Sela, Noa (Department of Plant Pathology and Weed Research. The Volcani Center. Israel) ; Marcet-Houben, Marina (Universitat Pompeu Fabra) ; Gabaldón, Toni (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Universitat Autònoma de Barcelona
Penicillium digitatum and Penicillium expansum are two closely related fungal plant pathogens causing green and blue mold in harvested fruit, respectively. The two species differ in their host specificity, being P. [...]
2016 - 10.1093/gbe/evv252
Genome biology and evolution, Vol. 8, Núm 1 (January 2016) , p. 218-227  
15.
18 p, 2.2 MB Aberrant epigenome in ‐derived dopaminergic neurons from Parkinson's disease patients / Fernández‐Santiago, Rubén (Universitat de Barcelona) ; Carballo‐Carbajal, Iria (Vall d'Hebron Institut de Recerca (VHIR)) ; Castellano, Giancarlo (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Torrent, Roger (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Richaud, Yvonne (Biomaterials and Nanomedicine (CIBER‐BBN). Centre for Networked Biomedical Research on Bioengineering) ; Sánchez‐Danés, Adriana (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Vilarrasa‐Blasi, Roser (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Sánchez‐Pla, Alex (Vall d'Hebron Institut de Recerca (VHIR)) ; Mosquera, José Luis (Universitat de Barcelona) ; Soriano, Jordi (Universitat de Barcelona) ; López‐Barneo, José (Universidad de Sevilla. Hospital Universitario Virgen del Rocío.) ; Canals, Josep M (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alberch, Jordi (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Vila Bover, Miquel (Vall d'Hebron Institut de Recerca (VHIR)) ; Consiglio, Antonella (University of Brescia and National Institute of Neuroscience) ; Martín‐Subero, José I (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ezquerra, Mario (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Tolosa, Eduardo (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)) ; Universitat Autònoma de Barcelona
The epigenomic landscape of Parkinson's disease () remains unknown. We performed a genomewide methylation and a transcriptome studies in induced pluripotent stem cell ()‐derived dopaminergic neurons (n) generated by cell reprogramming of somatic skin cells from patients with monogenic 2‐associated (L2) or sporadic (), and healthy subjects. [...]
2015 - 10.15252/emmm.201505439
EMBO Molecular Medicine, Vol. 7, Núm. 12 (October 2015) , p. 1529-1546  
16.
11 p, 3.5 MB Following the footprints of polymorphic inversions on SNP data : from detection to association tests / Cáceres, Alejandro (Centre de Recerca en Epidemiologia Ambiental (Barcelona)) ; González, Juan R. (Universitat Autonoma de Barcelona. Departament de Matemàtiques)
Inversion polymorphisms have important phenotypic and evolutionary consequences in humans. Two different methodologies have been used to infer inversions from SNP dense data, enabling the use of large cohorts for their study. [...]
2015 - 10.1093/nar/gkv073
Nucleic acids research, Vol. 43, issue 8 (April 2015) , e53  
17.
10 p, 752.3 KB Genome data from a sixteenth century pig illuminate modern breed relationships / Ramírez, Óscar (Consejo Superior de Investigaciones Científicas. Institut de Biologia Evolutiva) ; Burgos-Paz, William (Centre de Recerca en Agrigenòmica) ; Casas, E (Centre de Recerca en Agrigenòmica) ; Ballester Devis, Maria (Centre de Recerca en Agrigenòmica) ; Bianco, E. (Centre de Recerca en Agrigenòmica) ; Olalde, Iñigo (Consejo Superior de Investigaciones Científicas. Institut de Biologia Evolutiva) ; Santpere, G. (Consejo Superior de Investigaciones Científicas. Institut de Biologia Evolutiva) ; Novella Dalmau, Violeta (Universitat Autònoma de Barcelona. Departament de Prehistòria) ; Gut, M. (Centre Nacional d'Anàlisi Genòmica) ; Lalueza-Fox, Carles (Consejo Superior de Investigaciones Científicas. Institut de Biologia Evolutiva) ; Saña Seguí, Maria (Universitat Autònoma de Barcelona. Departament de Prehistòria) ; Pérez-Enciso, Miguel (Centre de Recerca en Agrigenòmica)
Ancient DNA (aDNA) provides direct evidence of historical events that have modeled the genome of modern individuals. In livestock, resolving the differences between the effects of initial domestication and of subsequent modern breeding is not straight forward without aDNA data. [...]
2014 - 10.1038/hdy.2014.81
Heredity, Vol. 114 (2015) , p. 175-184  
18.
8 p, 766.2 KB PopGenome : an efficient swiss army knife for population genomic analyses in R / Pfeifer, Bastian (Heinrich-Heine-Universität Düsseldorf) ; Wittelsbürger, Ulrich (Heinrich-Heine-Universität Düsseldorf) ; Ramos-Onsins, Sebastián E. (Centre de Recerca en Agrigenòmica) ; Lercher, Martin J. (Heinrich-Heine-Universität Düsseldorf)
Although many computer programs can perform population genetics calculations, they are typically limited in the analyses and data input formats they offer; few applications can process the large data sets produced by whole-genome resequencing projects. [...]
2014 - 10.1093/molbev/msu136
Molecular biology and evolution, Vol. 31 (April 2014) , p. 1929-1936  
19.
6 p, 420.8 KB ATP5H/KCTD2 locus is associated with Alzheimer's disease risk / Boada Rovira, Mercè (Hospital Universitari Vall d'Hebron) ; Antúnez, C. (University Hospital Virgen de la Arrixaca) ; Ramírez Lorca, Repo (Neocodex) ; DeStefano, Anita L. (Boston University School of Medicine) ; González Pérez, A. (Neocodex) ; Gayán, Javier (Neocodex) ; López Arrieta, Jesús (University Hospital La Paz-Cantoblanco) ; Ikram, M. Arfan (Erasmus MC University Medical Center) ; Hernández, Isabel (Institut Català de Neurociències Aplicades) ; Marín, J. (University Hospital Virgen de la Arrixaca) ; Galán, José Jorge (Neocodex) ; Bis, Joshua C. (University of Washington) ; Mauleón, Ana (Institut Català de Neurociènces Aplicades) ; Rosende-Roca, Maitée (Institut Català de Neurociènces Aplicades) ; Moreno Rey, Concha (Neocodex) ; Gudnasson, Vilmundur (Kopavogur University of Iceland) ; Morón, Francisco Jesús (Neocodex) ; Velasco, Juan (Neocodex) ; Carrasco, José Miguel (Neocodex) ; Alegret, Montserrat (Institut Català de Neurociències Aplicades) ; Espinosa, Ana (Institut Català de Neurociències Aplicades) ; Vinyes, Georgina (Institut Català de Neurociències Aplicades) ; Lafuente, Asunción (Institut Català de Neurociències Aplicades) ; Vargas, Liliana (Institut Català de Neurociències Aplicades) ; Fitzpatrick, Annette L. (University of Washington) ; Launer, Lenore Joy (National Institute on Aging) ; Sáez, María Eugenia (Neocodex) ; Vázquez, Enrique (Neocodex) ; Becker, James T. (University of Pittsburgh) ; López, Oscar L. (University of Pittsburgh School of Medicine) ; Serrano Ríos, Manuel (Hospital Clínico San Carlos) ; Tárraga, Lluís (Institut Català de Neurociènces Aplicades) ; van Duijn, Cornelia M. (Erasmus MC University Medical Center) ; Real, Luis Miguel (Neocodex) ; Seshadri, Sudha (National Heart, Lung and Blood Institute's Framingham Heart Study) ; Ruiz, Agustín (Department of Structural Genomics, Neocodex) ; Universitat Autònoma de Barcelona
To identify loci associated with Alzheimer disease, we conducted a three-stage analysis using existing genome-wide association studies (GWAS) and genotyping in a new sample. In Stage I, all suggestive single-nucleotide polymorphisms (at P <0. [...]
2014 - 10.1038/mp.2013.86
Molecular Psychiatry, Vol. 19, Issue 6 (June 2014) , p. 682-687  
20.
13 p, 981.6 KB Striking structural dynamism and nucleotide sequence variation of the transposon Galileo in the genome of Drosophila mojavensis / Marzo, Mar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bello, Xabier (Universidade de Santiago de Compostela. Departamento de Anatomía Patolóxica e Ciencias Forenses) ; Puig Font, Marta (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Maside, Xulio (Universidade de Santiago de Compostela. Departamento de Anatomía Patolóxica e Ciencias Forenses) ; Ruiz, Alfredo, (Ruiz Panadero) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Galileo is a transposable element responsible for the generation of three chromosomal inversions in natural populations of Drosophila buzzatii. Although the most characteristic feature of Galileo is the long internally-repetitive terminal inverted repeats (TIRs), which resemble the Drosophila Foldback element, its transposase-coding sequence has led to its classification as a member of the P-element superfamily (Class II, subclass 1, TIR order). [...]
2013 - 10.1186/1759-8753-4-6
Mobile DNA, Vol. 4 (2013) , art. 6  

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