Articles

Articles 30 records found  previous11 - 20next  jump to record: Search took 0.00 seconds. 
11.
12 p, 2.8 MB Gut microbiota linked to sexual preference and HIV infection / Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. IrsiCaixa) ; Guillén, Yolanda (Institut Germans Trias i Pujol. IrsiCaixa) ; Rivera, Javier (Institut Germans Trias i Pujol. IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. IrsiCaixa) ; Nowak, Piotr (Karolinska Universitetssjukhuset) ; Hildebrand, Falk (European Molecular Biology Laboratory) ; Zeller, Georg (European Molecular Biology Laboratory) ; Parera, Mariona (Institut Germans Trias i Pujol. IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. IrsiCaixa) ; Coll, Josep (Institut Germans Trias i Pujol. IrsiCaixa) ; Bravo, Isabel (Hospital Universitari Germans Trias i Pujol) ; Estany, Carla (Hospital Universitari Germans Trias i Pujol) ; Herrero, Cristina (Hospital Universitari Germans Trias i Pujol) ; Saz, Jorge (BCN Checkpoint,) ; Sirera, Guillem (Hospital Universitari Germans Trias i Pujol) ; Torrela, Ariadna (Hospital Universitari Vall d'Hebrón) ; Navarro, Jordi (Hospital Universitari Vall d'Hebrón) ; Crespo, Manel (Hospital Universitari Vall d'Hebrón) ; Brander, Christian (Institut Germans Trias i Pujol. IrsiCaixa) ; Negredo, Eugènia (Universitat de Vic) ; Blanco, Julià (Institut Germans Trias i Pujol. IrsiCaixa) ; Guarner, Francisco (Hospital Universitari Vall d'Hebrón) ; Calle, Maria Luz (Universitat de Vic) ; Bork, Peer (European Molecular Biology Laboratory) ; Sönnerborg, Anders (Karolinska Universitetssjukhuset) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa)
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance following HIV-1 infection, which have not been found in animal models or in studies matched for HIV-1 transmission groups. [...]
2016 - 10.1016/j.ebiom.2016.01.032
EBioMedicine, Vol. 5 (March 2016) , p. 135-146  
12.
11 p, 679.0 KB Does rapid HIV disease progression prior to combination antiretroviral therapy hinder optimal CD4 + T-cell recovery once HIV-1 suppression is achieved? / Jarrin, Inma (Instituto de Salud Carlos III, Madrid, Spain) ; Pantazis, Nikos (Athens University Medical School, Athens, Greece) ; Dalmau, Judith (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Phillips, Andrew N. (Research Department of Infection and Population Health) ; Olson, Ashley (Medical Research Council Clinical Trials Unit, University College London, London, UK) ; Mussini, Cristina (Institute of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy) ; Boufassa, Faroudy (Univ Paris-Sud, Le Kremlim Bicetre) ; Costagliola, Dominique (INSERM, Paris, France) ; Porter, Kholoud (Medical Research Council Clinical Trials Unit, University College London, London, UK) ; Blanco, Juliá (Universitat de Vic-Central de Catalunya, UVIC-UCC, Vic) ; Del Amo, Julia (Instituto de Salud Carlos III, Madrid, Spain) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
This article compares trends in CD4 + T-cell recovery and proportions achieving optimal restoration (≥500 cells/μl) after viral suppression following combination antiretroviral therapy (cART) initiation between rapid and nonrapid progressors. [...]
2015 - 10.1097/QAD.0000000000000805
AIDS (London, England), Vol. 29 (october 2015) , p. 2323-2333  
13.
10 p, 1.8 MB Recreational drug use among individuals living with HIV in Europe : review of the prevalence, comparison with the general population and HIV guidelines recommendations / Garin, Noe (Institut d'Investigació Biomèdica Sant Pau) ; Velasco, Cesar (ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic - Universitat de Barcelona) ; De Pourcq, Jan T. (Institut d'Investigació Biomèdica Sant Pau) ; Lopez, Belen (Pharmacy Department, Hospital del Mar - Parc de Salut Mar) ; Gutierrez, Maria del Mar (Grup de Recerca en HIV i AIDS-IR, Hospital de la Santa Creu i Sant Pau) ; Haro, Josep M. (Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III) ; Feliu, Anna (Institut d'Investigació Biomèdica Sant Pau) ; Mangues, Maria A. (Institut d'Investigació Biomèdica Sant Pau) ; Trilla, Antoni (ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic - Universitat de Barcelona)
Background: Adherence problems, interactions and higher rate of risk activities have been observed in HIV individuals using recreational drugs. Our aim was to describe recreational drug use in both HIV individuals and general population in Europe, and to assess at what extent HIV guidelines address this issue. [...]
2015 - 10.3389/fmicb.2015.00690
Frontiers in microbiology, Vol. 6 (july 2015)  
14.
7 p, 215.9 KB Evaluation of Rapid Progressors in HIV Infection as an Extreme Phenotype / Olson, Ashley D. (University College London. Medical Research Council Clinical Trials Unit (United Kingdom)) ; Guiguet, Marguerite (Université Pierre et Marie Curie (France)) ; Zangerle, Robert (Innsbruck Medical University (Austria)) ; Gill, John (University of Calgary (Canada)) ; Perez-Hoyos, Santiago (Vall d'Hebrón Institut de Recerca (VHIR)) ; Lodi, Sara (Instituto de Salud Carlos III) ; Ghosn, Jade (CHU Bicêtre. Service de Médecine Interne et Maladies Infectieuses (France)) ; Dorrucci, Maria (Istituto Superiore di Sanità (Italy)) ; Johnson, Anne (University College London. Institute of Epidemiology and Health Care (United Kingdom)) ; Sannes, Mette (Ulleval University Hospital (Norway)) ; Moreno, Santiago (Hospital Universitario Ramón y Cajal) ; Porter, Kholoud (University College London. Medical Research Council Clinical Trials Unit (United Kingdom)) ; Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. Rapid CD4 cell loss represents an HIV phenotype used to identify causal variants of accelerated disease progression. The optimal rate and threshold for identifying this extreme phenotype in recently infected individuals is unclear. [...]
2014 - 10.1097/QAI.0000000000000240
Journal of acquired immune deficiency syndromes (1999), Vol. 67, Issue 1 (September 2014) , p. 15-21  
15.
22 p, 834.8 KB EPICE-HIV: An Epidemiologic Cost-Effectiveness Model for HIV Treatment / Vandewalle, Björn (Exigo Consultores (Lisboa, Portugal)) ; Llibre Codina, Josep Maria (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Parienti, Jean-Jacques (Côte de Nacre University Hospital (Caen, França)) ; Ustianowski, Andrew (North Manchester General Hospital) ; Camacho, Ricardo (Catholic University of Leuven (Bèlgica)) ; Smith, Colette (University College London) ; Miners, Alec (London School of Hygiene and Tropical Medicine)) ; Ferreira, Diana (Exigo Consultores (Lisboa, Portugal)) ; Félix, Jorge (Exigo Consultores (Lisboa, Portugal))
The goal of this research was to establish a new and innovative framework for cost-effectiveness modeling of HIV-1 treatment, simultaneously considering both clinical and epidemiological outcomes. EPICE-HIV is a multi-paradigm model based on a within-host micro-simulation model for the disease progression of HIV-1 infected individuals and an agent-based sexual contact network (SCN) model for the transmission of HIV-1 infection. [...]
2016 - 10.1371/journal.pone.0149007
PloS one, Vol. 11 Núm. 2 (February 2016)  
16.
10 p, 1.6 MB Etravirine pharmacokinetics in HIV-infected pregnant women / Mulligan, Nikki (University of California (Estats Units d'Amèrica)) ; Schalkwijk, Stein (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; Best, Brookie M. (University of California (Estats Units d'Amèrica)) ; Colbers, Angela (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; Wang, Jiajia (Harvard School of Public Health (Boston, Estats Units d'Amèrica)) ; Capparelli, Edmund V. (University of California (Estats Units d'Amèrica)) ; Moltó Marhuenda, José ((Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Stek, Alice M. (University of Southern California. School of Medicina (Estats Units d'Amèrica)) ; Taylor, Graham (Imperial College Healthcare National Health Service Trust (Londres, Regne Unit)) ; Smith, Elizabeth (National Institute of Allergy and Infectious Diseases (Bethesda, Estats Units d'Amèrica)) ; Hidalgo Tenorio, Carmen (Hospital Virgen de las Nieves (Granada, Andalusia)) ; Chakhtoura, Nahida (Eunice Kennedy Shriver National Institute of Child Health and Human Development (Bethesda, Estats Units d'Amèrica)) ; Van Kasteren, Marjo (Saint Elisabeth Hospital (Tilburg, Països Baixos)) ; Fletcher, Courtney V. (University of Nebraska Medical Center (Omaha, Estats Units d'Amèrica)) ; Mirochnick, Mark (Boston University School of Medicine (Estats Units d'Amèrica)) ; Burger, David (Radboud University Nijmegen Medical Centre (Nijmegen, Països Baixos)) ; PANNA Network ; IMPAACT Network
BACKGROUND: The study goal was to describe etravirine pharmacokinetics during pregnancy and postpartum in HIV-infected women. METHODS: IMPAACT P1026s and PANNA are on-going, non-randomized, open-label, parallel-group, multi-center phase-IV prospective studies in HIV-infected pregnant women. [...]
2016 - 10.3389/fphar.2016.00239
Frontiers in Pharmacology, Vol. 7 Núm. 239 (August 2016)  
17.
13 p, 3.3 MB Individual-based modeling of tuberculosis in a user-friendly interface : understanding the epidemiological role of population heterogeneity in a city / Prats Soler, Clara (Universitat Politècnica de Catalunya) ; Montañola-Sales, Cristina (Universitat Politècnica de Catalunya) ; Gilabert-Navarro, Joan F. (Universitat Politècnica de Catalunya) ; Valls, Joaquim (Universitat Politècnica de Catalunya) ; Casanovas, Josep (Casanovas Garcia) (Universitat Politècnica de Catalunya) ; Vilaplana i Massaguer, Cristina (Institut Germans Trias i Pujol) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; López, Daniel (Universitat Politècnica de Catalunya) ; Universitat Autònoma de Barcelona
For millennia tuberculosis (TB) has shown a successful strategy to survive, making it one of the world's deadliest infectious diseases. This resilient behavior is based not only on remaining hidden in most of the infected population, but also by showing slow evolution in most sick people. [...]
2016 - 10.3389/fmicb.2015.01564
Frontiers in microbiology, Vol. 6, Núm. 1654 (January 2016)  
18.
5 p, 846.7 KB Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection / Sironi, Manuela (San Raffaele Scientific Institute (Milà, Itàlia)) ; Biasin, Mara (University of Milan (Itàlia)) ; Pontremoli, Chiara (San Raffaele Scientific Institute (Milà, Itàlia)) ; Cagliani, Rachele (San Raffaele Scientific Institute (Milà, Itàlia)) ; Saulle, Irma (University of Milan (Itàlia)) ; Trabattoni, Daria (University of Milan (Itàlia)) ; Vichi, Francesca (Santa Maria Annunziata Hospital (Florència, Itàlia)) ; Lo Caputo, Sergio (Santa Maria Annunziata Hospital (Florència, Itàlia)) ; Mazzotta, Francesco (Santa Maria Annunziata Hospital (Florència, Itàlia)) ; Aguilar-Jimenez, Wbeimar (Universidad de Antioquia (Medellín, Colòmbia)) ; Rugeles, María Teresa (Universidad de Antioquia (Medellín, Colòmbia)) ; Cedeno, Samandhy (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Sanchez, Jorge (Asociación Civil Impacta Salud y Educación (Lima, Perú)) ; Brander, Christian (Universitat de Vic) ; Clerici, Mario (Foundation ONLUS (Milà, Itàlia)) ; Universitat Autònoma de Barcelona
Abstract. BACKGROUND: The genetic bases of natural resistance to HIV-1 infection remain largely unknown. Recently, two genome-wide association studies suggested a role for variants within or in the vicinity of the CYP7B1 gene in modulating HIV susceptibility. [...]
2015 - 10.1186/s12977-015-0206-0
Retrovirology, Vol. 12 Núm. 80 (september 2015)  
19.
15 p, 3.1 MB HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells / Pino, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Benet, Susana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Erikson, Elina (University of Frankfurt (Alemanya)) ; Fernández Figueras, Maria Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guerrero, Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rausell, Antonio (University of Lausanne (Suïssa)) ; Ciuffi, Angela (University of Lausanne (Suïssa)) ; Keppler, Oliver T. (University of Frankfurt (Alemanya)) ; Telenti, Amalio (University of Lausanne (Suïssa)) ; Kräusslich, Hans-Georg (University of Heidelberg (Alemanya)) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Izquierdo Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Myeloid cells are key players in the recognition and response of the host against invading viruses. Paradoxically, upon HIV-1 infection, myeloid cells might also promote viral pathogenesis through trans-infection, a mechanism that promotes HIV-1 transmission to target cells via viral capture and storage. [...]
2015 - 10.1186/s12977-015-0160-x
Retrovirology, Vol 12, article 37 (May 2015)  
20.
23 p, 3.3 MB A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques / Mothe Pujadas, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hu, Xintao (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosati, Margherita (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kulkarni, Viraj (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Valentin, Antonio (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Alicea, Cándido (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Pilkington, Guy R. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Sardesai, Niranjan Y. (Inovio Pharmaceuticals) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Crespo, Manel (Hospital Universitari Vall d'Hebron) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Marco, Andrés (Centre Penitenciari d'Homes (Barcelona, Catalunya)) ; Mullins, James I. (University of Washington (Estats Units d'Amèrica)) ; Dorrell, Lucy (John Radcliffe Hospital (Oxford, Regne Unit)) ; Hanke, Tomáš (University of Oxford (Regne Unit)) ; Clotet i Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pavlakis, George N. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Felber, Barbara K. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
BACKGROUND: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been suboptimal T cell immunogen designs. [...]
2015 - 10.1186/s12967-015-0392-5
Journal of translational medicine, Vol. 13 Núm. 60 (february 2015)  

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