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10 p, 893.6 KB Efferocytosis Promotes Suppressive Effects on Dendritic Cells through Prostaglandin E2 Production in the Context of Autoimmunity / Pujol-Autonell, Irma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Planas, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Marin-Gallen, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Carrascal, Jorge (Universitat de Lleida. Departament de Ciències Bàsiques) ; Sánchez, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Marin, Ana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Puig Domingo, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pujol-Borrell, Ricardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Verdaguer, Joan (Universitat de Lleida. Departament de Ciències Bàsiques) ; Vives Pi, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Introduction: Efferocytosis is a crucial process by which apoptotic cells are cleared by phagocytes, maintaining immune tolerance to self in the absence of inflammation. Peripheral tolerance, lost in autoimmune processes, may be restored by the administration of autologous dendritic cells loaded with islet apoptotic cells in experimental type 1 diabetes. [...]
2013 - 10.1371/journal.pone.0063296
PloS one, Vol. 8 Issue 5 (May 2013) , p. e63296  
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