|
154.
|
|
10 p, 1.8 MB |
Manejo de la hiperglucemia con fármacos no insulínicos en pacientes adultos con diabetes tipo 2
/
Álvarez-Guisasola, Fernando (Centro de Salud Ribera del Órbigo, Benavides de Órbigo) ;
Orozco-Beltrán, Domingo (Centro de Salud Cabo Huertas, Alicante) ;
Cebrián-Cuenca, Ana M (Centro de Salud Cartagena Casco Antiguo, Cartagena) ;
Ruiz Quintero, Manuel Antonio (Centro de Salud Agost, Alicante) ;
Angullo-Martínez, Escarlata (Centro de Salud Escola Graduada, Palma de Mallorca) ;
Ávila Lachica, Luis (UGC Vélez Norte, consultorio de Almáchar, Almáchar) ;
Ortega Millán, Carlos (Centro de Salud de Pozoblanco, Pozoblanco) ;
Caride Miana, Elena (Medicina Familiar y Comunitaria, Centro de Salud Foietes, Benidorm) ;
Navarro-Pérez, Jorge (Hospital Clínic Universitari (València)) ;
Sagredo Perez, Julio (Centro de Salud Parque Europa, Pinto) ;
Barrot de la Puente, Joan (Centre de Salut Jordi Nadal i Fàbregas (Salt, Catalunya)) ;
Cos Claramunt, Francesc Xavier (Universitat Autònoma de Barcelona)
El adecuado tratamiento de la diabetes mellitus tipo 2 (DM2) incluye la alimentación saludable y el ejercicio (150 min/semana) como pilares básicos. Para el tratamiento farmacológico, la metformina es el fármaco de elección inicial, salvo contraindicación o intolerancia; en caso de mal control, se dispone de 8 familias terapéuticas (6 orales y 2 inyectables) como posibles combinaciones. [...]
2019 -  10.1016/j.aprim.2019.05.014
Atencion Primaria, Vol. 51 (july 2019) , p. 442-451
|
|
|
155.
|
|
11 p, 2.0 MB |
Optimal response to dimethyl fumarate is mediated by a reduction of Th1-like Th17 cells after 3 months of treatment
/
Mansilla Lopez, Maria Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Presas-Rodríguez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teniente Serra, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quirant, Bibiana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ramo-Tello, Cristina (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Dimethyl fumarate (DMF) is one of the most promising therapies for relapsing-remitting multiple sclerosis (RRMS) patients since it has shown immunomodulatory and neuroprotective effects. However, a percentage of RRMS patients do not exhibit an optimal response to DMF. [...]
2019 - 10.1111/cns.13142
CNS neuroscience & therapeutics, Vol. 25 (2019) , p. 995-1005
|
|
|
156.
|
|
8 p, 935.6 KB |
Testing the efficacy of INtegral Cognitive REMediation (INCREM) in major depressive disorder : study protocol for a randomized clinical trial
/
Vicent-Gil, Muriel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Raventós, Beatriz (Institut d'Investigació Biomèdica Sant Pau) ;
Marín-Martínez, Eduardo D. (Institut d'Investigació Biomèdica Sant Pau) ;
González-Simarro, Sara (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Arán, Anabel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bonnin, Caterina del Mar (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Trujols, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Pérez-Blanco, Josefina (Institut d'Investigació Biomèdica Sant Pau) ;
de Diego-Adeliño, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Puigdemont, Dolors (Institut d'Investigació Biomèdica Sant Pau) ;
Serra-Blasco, Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cardoner, N. (Narcís) (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau)
Given the limitation of pharmacological treatments to treat cognitive symptoms in patients with Major Depressive Disorder (MDD), cognitive remediation programs has been proposed as a possible procognitive intervention but findings are not conclusive. [...]
2019 - 10.1186/s12888-019-2117-4
BMC Psychiatry, Vol. 19 (may 2019)
|
|
|
157.
|
|
11 p, 2.0 MB |
Ethyl Pyruvate Induces Tolerogenic Dendritic Cells
/
Djedovic, Neda (University of Belgrade. Department of Immunology) ;
Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Jevtić, Bojan (University of Belgrade. Department of Immunology) ;
Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Saksida, Tamara (University of Belgrade. Department of Immunology) ;
Martínez-Cáceres, Eva M. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Miljković, Ðorđe (University of Belgrade. Department of Immunology)
Dendritic cells (DC) are professional antigen presenting cells that have a key role in shaping the immune response. Tolerogenic DC (tolDC) have immuno-regulatory properties and they are a promising prospective therapy for multiple sclerosis and other autoimmune diseases. [...]
2019 - 10.3389/fimmu.2019.00157
Frontiers in immunology, Vol. 10 (February 2019) , art. 157
|
|
|
158.
|
|
16 p, 1.6 MB |
Integrating clinical, molecular, proteomic and histopathological data within the tissue context : tissunomics
/
Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hümmer, Stefan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Peg, Vicente (Centro de Investigación Biomédica en Red de Cáncer) ;
Matías-Guiu, Xavier (Hospital Universitari de Bellvitge) ;
de Torres, Inés (Hospital Universitari Vall d'Hebron) ;
Castellvi, Josep (Centro de Investigación Biomédica en Red de Cáncer) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron) ;
Hernandez-Losa, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vall d'Hebron Institut de Recerca (VHIR)
Malignant tumours show a marked degree of morphological, molecular and proteomic heterogeneity. This variability is closely related to microenvironmental factors and the location of the tumour. The activation of genetic alterations is very tissue-dependent and only few tumours have distinct genetic alterations. [...]
2019 - 10.1111/his.13828
Histopathology, Vol. 75 (may 2019) , p. 4-19
|
|
|
159.
|
|
8 p, 674.6 KB |
DisProt : intrinsic protein disorder annotation in 2020
/
Hatos, András (University of Padova. Department of Biomedical Sciences) ;
Hajdu-Soltész, Borbála (MTA-ELTE Lendület Bioinformatics Research Group. Department of Biochemistry. Eötvös Loránd University) ;
Monzon, Alexander M. (Department of Biomedical Sciences. University of Padova) ;
Palopoli, Nicolas (Departamento de Ciencia y Tecnología. Universidad Nacional de Quilmes-CONICET) ;
Álvarez, Lucía (Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biotecnológicas IIBIO. Universidad Nacional de San Martín) ;
Aykac-Fas, Burcu (Computational Biology Laboratory. Danish Cancer Society Research Center) ;
Bassot, Claudio (Department of Biochemistry and Biophysics and Science for Life Laboratory. Stockholm University. Box 1031) ;
Benítez, Guillermo I. (Departamento de Ciencia y Tecnología. Universidad Nacional de Quilmes-CONICET) ;
Bevilacqua, Martina (Department of Biomedical Sciences. University of Padova) ;
Chasapi, Anastasia (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ;
Chemes, Lucía Beatriz (Universidad de Buenos Aires. Departamento de Fisiología y Biología Molecular y Celular) ;
Davey, Norman E. (Institute of Cancer Research (Londres, Regne Unit)) ;
Davidović, Radoslav (Laboratory for Bioinformatics and Computational Chemistry. Institute of Nuclear Sciences Vinca. University of Belgrade) ;
Dunker, A. Keith (Center for Computational Biology and Bioinformatics. Indiana University School of Medicine) ;
Elofsson, Arne (Department of Biochemistry and Biophysics and Science for Life Laboratory. Stockholm University. Box 1031) ;
Gobeill, Julien (Swiss Institute of Bioinformatics and HES-SO\HEG) ;
Foutel, Nicolás S. G. (Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biotecnológicas IIBIO. Universidad Nacional de San Martín) ;
Sudha, Govindarajan (Department of Biochemistry and Biophysics and Science for Life Laboratory. Stockholm University. Box 1031) ;
Guharoy, Mainak (VIB-VUB Center for Structural Biology. Flanders Institute for Biotechnology (VIB)) ;
Horvath, Tamas (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Iglesias, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Kajava, Andrey V. (Institut de Biologie Computationnelle(IBC)) ;
Kovacs, Orsolya P. (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Lamb, John (Department of Biochemistry and Biophysics and Science for Life Laboratory. Stockholm University. Box 1031) ;
Lambrughi, Matteo (Computational Biology Laboratory. Danish Cancer Society Research Center) ;
Lazar, Tamas (VIB-VUB Center for Structural Biology. Flanders Institute for Biotechnology (VIB)) ;
Leclercq, Jeremy Y. (Centre National de la Recherche Scientifique (França). Centre de Recherche en Biologie Cellulaire de Montpellier) ;
Leonardi, Emanuela (Fondazione Istituto di Ricerca Pediatrica (IRP). Città della Speranza) ;
Macedo-Ribeiro, Sandra (Instituto de Biologia Molecular e Celular (IBMC). Instituto de Investigação e Inovação em Saúde (i3S). Universidade Do Porto) ;
Macossay-Castillo, Mauricio (VIB-VUB Center for Structural Biology. Flanders Institute for Biotechnology (VIB)) ;
Maiani, Emiliano (Computational Biology Laboratory. Danish Cancer Society Research Center) ;
Manso, José A. (Instituto de Biologia Molecular e Celular (IBMC). Instituto de Investigação e Inovação em Saúde (i3S). Universidade Do Porto) ;
Marino-Buslje, Cristina (Fundación Instituto Leloir (Buenos Aires, Argentina)) ;
Martínez-Pérez, Elisabeth (Fundación Instituto Leloir (Buenos Aires, Argentina)) ;
Mészáros, Bálint (MTA-ELTE Lendület Bioinformatics Research Group. Department of Biochemistry. Eötvös Loránd University) ;
Mičetić, Ivan (Department of Biomedical Sciences. University of Padova) ;
Minervini, Giovanni (Department of Biomedical Sciences. University of Padova) ;
Murvai, Nikoletta (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Necci, Marco (Department of Biomedical Sciences. University of Padova) ;
Ouzounis, Christos A. (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ;
Pajkos, Mátyás (MTA-ELTE Lendület Bioinformatics Research Group. Department of Biochemistry. Eötvös Loránd University) ;
Paladin, Lisanna (Department of Biomedical Sciences. University of Padova) ;
Pancsa, Rita (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Papaleo, Elena (Translational Disease Systems Biology. Faculty of Health and Medical Sciences. Novo Nordisk Foundation Center. Protein Research University of Copenhagen) ;
Parisi, Gustavo (Departamento de Ciencia y Tecnología. Universidad Nacional de Quilmes-CONICET) ;
Pasche, Emilie (Swiss Institute of Bioinformatics and HES-SO\HEG) ;
Barbosa Pereira, Pedro José (Instituto de Biologia Molecular e Celular (IBMC). Instituto de Investigação e Inovação em Saúde (i3S). Universidade Do Porto) ;
Promponas, Vasilis J. (Bioinformatics Research Laboratory. Department of Biological Sciences. University of Cyprus) ;
Pujols Pujol, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Quaglia, Federica (Department of Biomedical Sciences. University of Padova) ;
Ruch, Patrick (Swiss Institute of Bioinformatics and HES-SO\HEG) ;
Salvatore, Marco (Department of Biochemistry and Biophysics and Science for Life Laboratory. Stockholm University. Box 1031) ;
Schad, Eva (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Szabo, Beata (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Szaniszló, Tamás (MTA-ELTE Lendület Bioinformatics Research Group. Department of Biochemistry. Eötvös Loránd University) ;
Tamana, Stella (Bioinformatics Research Laboratory. Department of Biological Sciences. University of Cyprus) ;
Tantos, Agnes (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Veljkovic, Nevena (Laboratory for Bioinformatics and Computational Chemistry. Institute of Nuclear Sciences Vinca. University of Belgrade) ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Vranken, Wim (Interuniversity Institute of Bioinformatics in Brussels (IB2). ULB-VUB) ;
Dosztányi, Zsuzsanna (MTA-ELTE Lendület Bioinformatics Research Group. Department of Biochemistry. Eötvös Loránd University) ;
Tompa, Peter (Institute of Enzymology. Research Centre for Natural Sciences. Hungarian Academy of Sciences) ;
Tosatto, Silvio (CNR Institute of Neurosceince) ;
Piovesan, Damiano (Department of Biomedical Sciences. University of Padova)
The Database of Protein Disorder (DisProt, URL: https://disprot. org) provides manually curated annotations of intrinsically disordered proteins from the literature. Here we report recent developments with DisProt (version 8), including the doubling of protein entries, a new disorder ontology, improvements of the annotation format and a completely new website. [...]
2020 - 10.1093/nar/gkz975
Nucleic acids research, Vol. 48, issue D1 (Jan. 2020) , p. D269-D276
|
|
|
160.
|
|
13 p, 1.9 MB |
Recombinant protein-based nanoparticles : elucidating their inflammatory effects in vivo and their potential as a new therapeutic format
/
Gifre-Renom, Laia (Institut de Recerca i Tecnologia Agroalimentàries) ;
Ugarte-Berzal, Estefanía (Katholieke Universiteit Leuven. Department of Microbiology, Immunology and Transplantation) ;
Martens, Erik (Katholieke Universiteit Leuven. Department of Microbiology, Immunology and Transplantation) ;
Boon, Lise (Katholieke Universiteit Leuven. Department of Microbiology, Immunology and Transplantation) ;
Cano-Garrido, Olivia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Martínez-Núñez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Luque, Teresa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Roca-Pinilla, Ramon (Institut de Recerca i Tecnologia Agroalimentàries) ;
Conchillo-Solé, Oscar (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Opdenakker, Ghislain (Katholieke Universiteit Leuven. Department of Microbiology, Immunology and Transplantation) ;
Garcia-Fruitos, Elena (Institut de Recerca i Tecnologia Agroalimentàries) ;
Arís i Giralt, Anna (Institut de Recerca i Tecnologia Agroalimentàries)
Bacterial inclusion bodies (IBs) are protein-based nanoparticles of a few hundred nanometers formed during recombinant protein production processes in different bacterial hosts. IBs contain active protein in a mechanically stable nanostructured format that has been broadly characterized, showing promising potential in different fields such as tissue engineering, protein replacement therapies, cancer, and biotechnology. [...]
2020 - 10.3390/pharmaceutics12050450
Pharmaceutics, Vol. 12, issue 5 (2020) , art. 450
|
|
|
161.
|
|
|
162.
|
|
18 p, 302.4 KB |
On farthest Voronoi cells
/
Goberna, Miguel Ángel (Universitat d'Alacant) ;
Martínez Legaz, Juan Enrique (Universitat Autònoma de Barcelona) ;
Todorov, Maxim (Universidad de las Américas Puebla)
Given an arbitrary set T in the Euclidean space Rn, whose elements are called sites, and a particular site s, the farthest Voronoi cell of s, denoted by FT(s), consists of all points which are farther from s than from any other site. [...]
2019 - 10.1016/j.laa.2019.09.002
Linear Algebra and its Applications, Vol. 583 (December 2019) , p. 306-322
|
|
|
163.
|
|
14 p, 1.9 MB |
MAP7 and MUCL1 are biomarkers of Vitamin D3-induced tolerogenic dendritic cells in multiple sclerosis patients
/
Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ardiaca-Martínez, Alicia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Presas-Rodríguez, Silvia (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ten Brinke, Anja (Amsterdam UMC. University Medical Center) ;
Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The administration of autologous tolerogenic dendritic cells (tolDC) has become a promising alternative for the treatment of autoimmune diseases, such as multiple sclerosis (MS). Specifically, the use of vitamin D3 for the generation of tolDC (vitD3-tolDC) constitutes one of the most widely studied approaches, as it has evidenced significant immune regulatory properties, both in vitro and in vivo. [...]
2019 - 10.3389/fimmu.2019.01251
Frontiers in immunology, Vol. 10 (June 2019) , art. 1251
|
|
guest ::
email alert
or subscribe to the 
RSS feed.
