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Articles 59 records found  beginprevious16 - 25nextend  jump to record: Search took 0.00 seconds. 
16.
15 p, 1.0 MB Circulating AQP4 Levels in Patients with Cerebral Amyloid Angiopathy-Associated Intracerebral Hemorrhage / Marazuela, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bonaterra-Pastra, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Faura, Júlia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Penalba, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pizarro Gonzálvez, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pancorbo, Olalla (Hospital Universitari Vall d'Hebron) ; Rodríguez-Luna, David (Hospital Universitari Vall d'Hebron) ; Vert, Carla (Hospital Universitari Vall d'Hebron) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; Pujadas, Francesc (Hospital Universitari Vall d'Hebron) ; Freijo, M. Mar (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Tur, Silvia (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Martínez-Zabaleta, Maite (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ; Cardona, Pere-Joan (Hospital Universitari de Bellvitge) ; Vera, Rocío (Hospital Universitario Ramón y Cajal (Madrid)) ; Lebrato-Hernández, Lucia (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Arenillas, Juan F.. (Universidad de Valladolid) ; Pérez-Sánchez, Soledad (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ; Montaner, Joan (Universidad de Sevilla) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernandez Guillamon, Maria Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage (ICH) in elderly patients. Growing evidence suggests a potential role of aquaporin 4 (AQP4) in amyloid-beta-associated diseases, including CAA pathology. [...]
2021 - 10.3390/jcm10050989
Journal of clinical medicine, Vol. 10 (march 2021)  
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17.
5 p, 449.3 KB Prophylactic Effect of a Therapeutic Vaccine against TB Based on Fragments of Mycobacterium tuberculosis / Vilaplana, Cristina (Institut Germans Trias i Pujol) ; Gil, Olga (Institut Germans Trias i Pujol) ; Cáceres, Neus (Institut Germans Trias i Pujol) ; Pinto, Sergio (Institut Germans Trias i Pujol) ; Díaz, Jorge (Institut Germans Trias i Pujol) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol)
The prophylactic capacity of the RUTI® vaccine, based on fragmented cells of Mycobacterium tuberculosis, has been evaluated in respect to aerosol challenge with virulent bacilli. Subcutaneous vaccination significantly reduced viable bacterial counts in both lungs and spleens of C57Bl mice, when challenged 4 weeks after vaccination. [...]
2011 - 10.1371/journal.pone.0020404
PloS one, Vol. 6 (may 2011)  
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18.
8 p, 406.8 KB To Achieve an Earlier IFN-γ Response Is Not Sufficient to Control Mycobacterium tuberculosis Infection in Mice / Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Prats, Clara (Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear) ; Marzo, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Barril, Carles (Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear) ; Vegué, Marina (Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear) ; Díaz, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Valls, Joaquim (Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear) ; López, Daniel (Universitat Politècnica de Catalunya. Departament de Física i Enginyeria Nuclear) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
The temporo-spatial relationship between the three organs (lung, spleen and lymph node) involved during the initial stages of Mycobacterium tuberculosis infection has been poorly studied. As such, we performed an experimental study to evaluate the bacillary load in each organ after aerosol or intravenous infection and developed a mathematical approach using the data obtained in order to extract conclusions. [...]
2014 - 10.1371/journal.pone.0100830
PloS one, Vol. 9 (june 2014)  
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19.
5 p, 661.4 KB Multiple Consecutive Infections Might Explain the Lack of Protection by BCG / Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Although contacts between tuberculosis patients may result in multiple consecutive infections (MCI), no experimental animal models consider this fact when used in basic studies. Moreover, the current TB vaccine (BCG) has demonstrated a limited protection in humans. [...]
2014 - 10.1371/journal.pone.0094736
PloS one, Vol. 9 (april 2014)  
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20.
10 p, 1.1 MB Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI : Randomized, Placebo-Controlled Phase II Clinical Trial in Patients with Latent Tuberculosis Infection / Nell, Andre S. (PAREXEL Early Phase Clinical Unit, Bloemfontein, South Africa) ; D'lom, Eva (PAREXEL International, Madrid, Spain) ; Bouic, Patrick (Synexa Life Sciences, Cape Town, South Africa) ; Sabaté, Montserrat (TFS Develop, Barcelona, Catalonia, Spain) ; Bosser, Ramon (Janus Developments (Barcelona, Catalunya)) ; Picas, Jordi (Archivel Farma) ; Amat, Mercè (Archivel Farma) ; Churchyard, Gavin (The Aurum Institute, Johannesburg, South Africa) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
To evaluate the safety, tolerability and immunogenicity of three different doses (5, 25 and 50 µg) of the novel antituberculous vaccine RUTI compared to placebo in subjects with latent tuberculosis infection. [...]
2014 - 10.1371/journal.pone.0089612
PloS one, Vol. 9 (february 2014)  
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21.
12 p, 3.1 MB A Beneficial Effect of Low-Dose Aspirin in a Murine Model of Active Tuberculosis / Kroesen, Vera Marie (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez-Martínez, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García, Eric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rosales, Yaiza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Díaz, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martín-Céspedes, Montse (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
An excessive, non-productive host-immune response is detrimental in active, chronic tuberculosis (TB) disease as it typically leads to tissue damage. Given their anti-inflammatory effect, non-steroidal anti-inflammatory drugs can potentially attenuate excessive inflammation in active TB disease. [...]
2018 - 10.3389/fimmu.2018.00798
Frontiers in immunology, Vol. 9 (april 2018)  
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22.
26 p, 5.0 MB A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis / Infectious Diseases department, Centre d'Infectiologie, Bât Domilyon, Lyon ; Coupet, Charles-Antoine (Infectious Diseases department, Centre d'Infectiologie, Bât Domilyon, Lyon) ; Gouanvic, Marie (Infectious Diseases department, Centre d'Infectiologie, Bât Domilyon, Lyon) ; Schmitt, Doris (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Ray, Aurélie (Infectious Diseases department, Centre d'Infectiologie, Bât Domilyon, Lyon) ; Hoffmann, Chantal (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Schultz, Huguette (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Tyagi, Sandeep (Johns Hopkins University, Baltimore) ; Soni, Heena (Johns Hopkins University, Baltimore) ; Converse, Paul J. (Johns Hopkins University, Baltimore) ; Arias, Lilibeth (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Kleinpeter, Patricia (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Sansas, Benoît (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Mdluli, Khisimuzi (Global Alliance for Tuberculosis Drug Development, New York) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Nuermberger, Eric (Johns Hopkins University, Baltimore, Maryland) ; Marchand, Jean-Baptiste (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Silvestre, Nathalie (Boulevard Gonthier d'Andernach, Parc d'innovation, Illkirch-Graffenstaden) ; Inchauspé, Geneviève (Infectious Diseases department, Centre d'Infectiologie, Bât Domilyon, Lyon)
Despite the existence of the prophylactic Bacille Calmette-Guérin (BCG) vaccine, infection by Mycobacterium tuberculosis (Mtb) remains a major public health issue causing up to 1. 8 million annual deaths worldwide. [...]
2018 - 10.1371/journal.pone.0196815
PloS one, Vol. 13 (may 2018)  
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23.
11 p, 2.5 MB High Antigen Dose Is Detrimental to Post-Exposure Vaccine Protection against Tuberculosis / Billeskov, Rolf (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen) ; Lindenstrøm, Thomas (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen) ; Woodworth, Joshua (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen) ; Vilaplana, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Cassidy, Joseph P. (University College Dublin, Belfield) ; Mortensen, Rasmus (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen) ; Agger, Else Marie (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen) ; Andersen, Peter (Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen)
Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis (TB), causes 1. 8M deaths annually. The current vaccine, BCG, has failed to eradicate TB leaving 25% of the world's population with latent Mtb infection (LTBI), and 5-10% of these people will reactivate and develop active TB. [...]
2018 - 10.3389/fimmu.2017.01973
Frontiers in immunology, Vol. 8 (january 2018)  
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24.
849.8 KB Regulatory T Cells in Mycobacterium tuberculosis Infection / Cardona, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Anti-inflammatory regulatory T cells have lately attracted attention as part of the immune response to Mycobacterium tuberculosis infection, where they counterbalance the protective but pro-inflammatory immune response mediated by Th17 cells and especially by the better-known Th1 cells. [...]
2019 - 10.3389/fimmu.2019.02139
Frontiers in immunology, Vol. 10 (september 2019)  
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25.
13 p, 1.3 MB Moving forward through the in silico modeling of tuberculosis : a further step with UISS-TB / Russo, Giulia (University of Catania) ; Sgroi, Giuseppe (University of Catania) ; Parasiliti Palumbo, Giuseppe Alessandro (University of Catania) ; Pennisi, Marzio (University of Eastern Piedmont) ; Juarez, Miguel A. (University of Sheffield) ; Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Motta, Santo (National Research Council of Italy) ; Walker, Kenneth B. (TuBerculosis Vaccine Initiative (TBVI)) ; Fichera, Epifanio (Etna Biotech S.r.l) ; Viceconti, Marco (University of Bologna) ; Pappalardo, Francesco (University of Catania) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
In 2018, about 10 million people were found infected by tuberculosis, with approximately 1. 2 million deaths worldwide. Despite these numbers have been relatively stable in recent years, tuberculosis is still considered one of the top 10 deadliest diseases worldwide. [...]
2020 - 10.1186/s12859-020-03762-5
BMC bioinformatics, Vol. 21 (december 2020)  
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Articles : 59 records found   beginprevious16 - 25nextend  jump to record:
See also: similar author names
4 Cardona, P.
6 Cardona, Paula
6 Cardona, Paula
1 Cardona, Pere
97 Cardona, Pere-Joan
11 Cardona, Pere-Joan,
1 Cardona, Pere-Joan.
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