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Articles 133 records found  beginprevious23 - 32nextend  jump to record: Search took 0.01 seconds. 
23.
8 p, 641.4 KB Safety and efficacy of ribociclib plus letrozole in patients with HR+, HER2- advanced breast cancer : Results from the Spanish sub-population of the phase 3b CompLEEment-1 trial / Salvador Bofill, Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Moreno Anton, Fernando (Hospital Clínico San Carlos (Madrid)) ; Rodriguez Sanchez, Cesar Augusto (Hospital Universitario de Salamanca-IBSAL) ; Galve Calvo, Elena (Hospital de Basurto (Bilbao, Biscaia)) ; Hernando Melia, Cristina (Hospital Clínic Universitari (València)) ; Ciruelos, Eva (Hospital Universitario 12 de Octubre (Madrid)) ; Vidal Losada, Maria (Hospital Clínic i Provincial de Barcelona) ; Jiménez-Rodriguez, Begoña (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; de la Cruz Merino, Luis (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ; Martínez Jañez, Noelia (Hospital Universitario Ramón y Cajal (Madrid)) ; Villanueva Vazquez, Rafael (Institut Català d'Oncologia) ; de Toro Salas, Ruben (Hospital Universitario de Jerez (Jerez de la Frontera)) ; Antón, Antonio (Hospital Universitario Miguel Servet (Saragossa)) ; Alvarez Lopez, Isabel Manuela (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Gavila Gregori, Joaquin (Fundació Institut Valencià d'Oncologia) ; Quiroga Garcia, Vanesa (Institut Català d'Oncologia) ; Vicente Rubio, Elena (Hospital Universitario Insular de Gran Canaria) ; de la Haba Rodríguez, Juan Rafael (Universidad de Córdoba) ; Gonzalez-Santiago, Santiago (Hospital Universitario San Pedro de Alcántara) ; Diaz Fernandez, Nieves (Hospital Universitario San Juan de Alicante) ; Barnadas i Molins, Agustí (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Cantos Sanchez de Ibargüen, Blanca (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Delgado Mingorance, Juan Ignacio (Hospital Universitario Infanta Cristina) ; Bellet Ezquerra, Meritxell (Vall d'Hebron Institut d'Oncologia) ; de Casa, Sonia (Novartis Farmacèutica, SA) ; Gimeno, Asuncion (Novartis Farmacèutica, SA) ; Martin, Miguel (Hospital General Universitario Gregorio Marañón) ; Universitat Autònoma de Barcelona
Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality in Spanish women. Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer (ABC) vs. [...]
2022 - 10.1016/j.breast.2022.09.006
Breast, Vol. 66 (september 2022) , p. 77-84  
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24.
12 p, 815.7 KB Clearance of ctDNA in triple-negative and HER2-positive breast cancer patients during neoadjuvant treatment is correlated with pathologic complete response / Ciriaco, Nikaoly (Hospital del Mar (Barcelona, Catalunya)) ; Zamora, Esther (Hospital Universitari Vall d'Hebron) ; Escrivá-de-Romaní, Santiago (Hospital Universitari Vall d'Hebron) ; Miranda Gómez, Ignacio (Hospital Universitari Vall d'Hebron) ; Jiménez Flores, José (Vall d'Hebron Institut d'Oncologia) ; Saura, Cristina (Hospital Universitari Vall d'Hebron) ; Sloane, Hillary ; Starus, Anna ; Fredebohm, Johannes ; Georgieva, Lucy ; Speight, Graham ; Jones, Frederick ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron) ; Espinosa-Bravo, Martín (Hospital Universitari Vall d'Hebron) ; Peg, Vicente (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Although the standard of care is to perform surgery of primary breast cancer (BC) after neoadjuvant chemotherapy (NAC), for certain patients achieving clinical complete response (cCR) and pathologic complete response (pCR), omission of surgical treatment may be an option. [...]
2022 - 10.1177/17588359221139601
Therapeutic Advances in Medical Oncology, Vol. 14 (november 2022)  
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25.
14 p, 2.0 MB Quality of life with palbociclib plus fulvestrant versus placebo plus fulvestrant in postmenopausal women with endocrine-sensitive hormone receptor-positive and HER2-negative advanced breast cancer : patient-reported outcomes from the FLIPPER trial / Tibau Martorell, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ; Martínez, M. Teresa ; Ramos, Manuel ; de la Cruz Merino, Luis ; Santaballa, Ana ; O'Connor, Miriam ; Martínez-Jañez, Noelia ; Moreno, Fernando ; Fernández, Isaura ; Virizuela, Juan Antonio ; Alarcón, Jesús ; de la Haba Rodríguez, Juan Rafael ; Sánchez-Rovira, Pedro ; Albacar, Cinta Rosa ; Bueno Muiño, Coralia ; Kelly, Catherine ; Casas, Maribel ; Bezares, Susana ; Rosell, Libertad ; Albanell Mestres, Joan (Hospital del Mar (Barcelona, Catalunya)) ; Universitat Autònoma de Barcelona
In the FLIPPER trial, palbociclib/fulvestrant significantly improved progression-free survival (PFS) compared with placebo/fulvestrant in postmenopausal women with HR+/HER2− advanced breast cancer (ABC). [...]
2023 - 10.1177/17588359221148921
Therapeutic Advances in Medical Oncology, Vol. 15 (january 2023)  
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26.
8 p, 998.3 KB Evidence-based guidelines for hypofractionated radiation in breast cancer : conclusions of the Catalan expert working group / Eraso, Arantxa (Institut Català d'Oncologia (Girona, Catalunya). Radiation Oncology Department) ; Sanz, Javier (Hospital del Mar (Barcelona, Catalunya)) ; Mollà, Meritxell (Hospital Clínic i Provincial de Barcelona) ; Reyes López, Victoria (Hospital Universitari Vall d'Hebron) ; Pedro, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Arenas, Meritxell (Hospital Universitari Sant Joan de Reus (Tarragona)) ; Martinez, Evelyn (Institut Català d'Oncologia. Hospital Duran i Reynals. Servei d'Oncologia Radioteràpica) ; Ballester Alabau, Rosa (Institut Català d'Oncologia Badalona. Servei d'Oncologia Radioteràpica) ; Cambra, Maria José (Hospital General de Catalunya. Servei d'Oncologia Radioteràpica) ; García, Virginia (Hospital Universitari Arnau de Vilanova) ; Prades, Joan Lluis (Pla Director d'Oncologia de Catalunya. Institut Català d'Oncologia. Hospital Duran i Reynals) ; Borras, Josep M. (Pla Director d'Oncologia de Catalunya. Institut Català d'Oncologia. Hospital Duran i Reynals) ; Algara, Manuel (Institut Hospital del Mar d'Investigacions Mèdiques)
Introduction: Daily, moderate hypofractionation has become standard treatment for breast cancer following breast-conserving surgery, although substantial variation exists in its use. This paper describes the generation of consensus-based recommendations for the utilisation of this therapy at the healthcare system level and compares these to American Society for Radiation Oncology (ASTRO) guidelines. [...]
2022 - 10.1007/s12094-022-02798-8
Clinical & Translational Oncology, Vol. 24 Núm. 8 (august 2022) , p. 1580-1587  
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27.
19 p, 2.3 MB B Cells in Breast Cancer Pathology / Li, Mengyuan (King's College London) ; Quintana, Angela (Vall d'Hebron Institut d'Oncologia) ; Alberts, Elena (The Francis Crick Institute) ; Hung, Miu Shing (King's College London) ; Boulat, Victoire (King's College London) ; Martí, Mercè (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Grigoriadis, Anita (School of Cancer and Pharmaceutical Sciences) ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
B cells in the tumour microenvironment and lymph nodes have affirmed their role in breast cancer pathology. Multiplex imaging, single cell, and spatial transcriptomics of cancer patients' breast carcinomas and lymph nodes have illustrated the diversity and spatial context of B cells in this disease. [...]
2023 - 10.3390/cancers15051517
Cancers, Vol. 15, Issue 5 (February 2023) , art. 1517  
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28.
16 p, 581.3 KB Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer : a systematic review for the European Commission Initiative on Breast Cancer (ECIBC) / Canelo Aybar, Carlos Gilberto (Institut d'Investigació Biomèdica Sant Pau) ; Posso, M. (Hospital del Mar (Barcelona, Catalunya)) ; Montero, N. (Centro Cochrane Iberoamericano) ; Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ; Saz-Parkinson, Zuleika (European Commission. Joint Research Centre (JRC)) ; Duffy, Stephen W (Wolfson Institute of Preventive Medicine. Queen Mary University of London) ; Follmann, M. (German Cancer Society) ; Gräwingholt, A. (Radiologie am Theater) ; Giorgi Rossi, P. (Epidemiology Unit. Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia) ; Alonso-Coello, Pablo (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Universitat Autònoma de Barcelona
Background: Although mammography screening is recommended in most European countries, the balance between the benefits and harms of different screening intervals is still a matter of debate. This review informed the European Commission Initiative on Breast Cancer (BC) recommendations. [...]
2022 - 10.1038/s41416-021-01521-8
British Journal of Cancer, Vol. 126 Núm. 4 (september 2022) , p. 673-688  
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29.
10 p, 7.6 MB Cell Senescence-Related Pathways Are Enriched in Breast Cancer Patients With Late Toxicity After Radiotherapy and Low Radiation-Induced Lymphocyte Apoptosis / Aguado-Flor, Ester (Vall d'Hebron Institut d'Oncologia) ; Fuentes-Raspall, María J. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Gonzalo, Ricardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alonso, Carmen (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Ramon y Cajal, Teresa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Fisas, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Seoane, A. (Hospital Universitari Vall d'Hebron) ; Sánchez, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Giralt López de Sagredo, Jordi (Vall d'Hebron Institut d'Oncologia) ; Diez, Orland (Hospital Universitari Vall d'Hebron) ; Gutiérrez-Enríquez, Sara (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Background: Radiation-induced late effects are a common cause of morbidity among cancer survivors. The biomarker with the best evidence as a predictive test of late reactions is the radiation-induced lymphocyte apoptosis (RILA) assay. [...]
2022 - 10.3389/fonc.2022.825703
Frontiers in Oncology, Vol. 12 (24 2022) , p. 825703  
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30.
10 p, 2.5 MB Long-Term Cardiac Safety and Survival Outcomes of Neoadjuvant Pegylated Liposomal Doxorubicin in Elderly Patients or Prone to Cardiotoxicity and Triple Negative Breast Cancer. Final Results of the Multicentre Phase II CAPRICE Study / Gil-Gil, M.J. (Institut Català d'Oncologia) ; Bellet Ezquerra, Meritxell (Hospital Universitari Vall d'Hebron) ; Bergamino, M. (Institut Català d'Oncologia) ; Morales, S. (Hospital Arnau de Vilanova (València)) ; Barnadas i Molins, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Manso, Luis (Hospital Universitario 12 de Octubre (Madrid)) ; Saura, Cristina (Hospital Universitari Vall d'Hebron) ; Fernández-Ortega, A. (Institut Català d'Oncologia) ; Garcia-Martinez, E. (Hospital General Universitario Morales Meseguer (Múrcia)) ; Martinez-Jañez, N. (Hospital Universitario Ramón y Cajal (Madrid)) ; Melé, M. (Hospital Sant Joan) ; Villagrasa, P. (SOLTI Breast Cancer Research Group) ; Céliz, Pamela (SOLTI Breast Cancer Research Group) ; Perez Martin, X. (Institut Català d'Oncologia. L'Hospitalet) ; Ciruelos, Eva (Department of Medical Oncology. Hospital) ; Pernas, S. (Institut Català d'Oncologia)
Background: The CAPRICE trial was designed to specifically evaluate neoadjuvant pegylated liposomal doxorubicin (PLD) in elderly patients or in those with other cardiovascular risk factors in whom conventional doxorubicin was contraindicated. [...]
2021 - 10.3389/fonc.2021.645026
Frontiers in Oncology, Vol. 11 (september 2021) , p. 645026  
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31.
9 p, 747.5 KB Predictive and prognostic value of total tumor load in sentinel lymph nodes in breast cancer patients after neoadjuvant treatment using one-step nucleic acid amplification : the NEOVATTL study / Vieites, B. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; López-García, M. (Centro de Investigación Biomédica en Red de Cáncer) ; Martín-Salvago, M.D. (Hospital Universitario Materno-Infantil) ; Ramirez-Tortosa, C.L. (Hospital Universitario Materno-Infantil) ; Rezola, R. (Onkologikoa Kutxa Fundazioa) ; Sancho, M. (Hospital Universitario de Salamanca) ; López Vilaró, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Villardell, F. (Hospital Universitario Arnau de Vilanova) ; Burgués, Octavio (Hospital Clínic Universitari (València)) ; Fernández-Rodriguez, B. (Complejo Hospitalario Universitario de Santiago de Compostela) ; Alfaro, L. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Peg, Vicente (Centro de Investigación Biomédica en Red de Cáncer)
Objective: To evaluate the predictive and prognostic value of total tumor load (TTL) in sentinel lymph nodes (SLNs) in patients with infiltrating breast cancer after neoadjuvant systemic therapy (NST). [...]
2021 - 10.1007/s12094-020-02530-4
Clinical & Translational Oncology, Vol. 23 Núm. 7 (july 2021) , p. 1377-1385  
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32.
13 p, 10.7 MB Efficient tumor eradication at ultralow drug concentration via externally controlled and boosted metallic iron magnetoplasmonic nanocapsules / Fluksman, Arnon (The Hebrew University of Jerusalem. Institute for Drug Research) ; Lafuente, Aritz (Institut Català de Nanociència i Nanotecnologia) ; Li, Zhi (Institut Català de Nanociència i Nanotecnologia) ; Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física) ; Lope-Piedrafita, Silvia (Universitat Autònoma de Barcelona) ; Esplandiu Egido, Maria José (Institut Català de Nanociència i Nanotecnologia) ; Nogués, Josep (Institut Català de Nanociència i Nanotecnologia) ; Gómez Roca, Alejandro (Institut Català de Nanociència i Nanotecnologia) ; Benny, Ofra (The Hebrew University of Jerusalem. Institute for Drug Research) ; Sepúlveda, Borja (Institut de Microelectrònica de Barcelona)
With the aim to locally enhance the efficacy of cancer nanotherapies, here we present metal iron based magnetoplasmonic drug-loaded nanocapsules (MAPSULES), merging powerful external magnetic concentration in the tumor and efficient photothermal actuation to locally boost the drug therapeutic action at ultralow drug concentrations. [...]
2023 - 10.1021/acsnano.2c05733
ACS nano, Vol. 17, Issue 3 (February 2023) , p. 1946-1958  
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