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Articles 84 records found  beginprevious58 - 67nextend  jump to record: Search took 0.01 seconds. 
58.
28 p, 1.0 MB Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins / Huertas, César S. (Institut Català de Nanociència i Nanotecnologia) ; Aviñó, Ana (Institut de Química Avançada de Catalunya) ; Kurachi, Cristina (Institut Català de Nanociència i Nanotecnologia) ; Piqué, Albert (Institut Català de Nanociència i Nanotecnologia) ; Sandoval, Juan (Institut d'Investigació Biomèdica de Bellvitge) ; Eritja, Ramon (Institut de Química Avançada de Catalunya) ; Esteller, M. (Institució Catalana de Recerca i Estudis Avançats) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Cancer diagnosis continuously evolves due to the better understanding of tumorigenic processes. DNA-methylation is consolidated as an effective biomarker for cancer prognosis and diagnostic even in tumors of unknown origin. [...]
2018 - 10.1016/j.bios.2018.08.027
Biosensors & bioelectronics, Vol. 120 (November 2018) , p. 47-54  
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59.
16 p, 1.2 MB Nanoplasmonic biosensor device for the monitoring of acenocoumarol therapeutic drug in plasma / Peláez Gutiérrez, Enelia Cristina (Institut Català de Nanociència i Nanotecnologia) ; Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ; Portela Otaño, Alejandro (Institut Català de Nanociència i Nanotecnologia) ; Salvador, J. Pablo (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Marco, María Pilar (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Acenocoumarol (Sintrom®) is an oral anticoagulant prescribed for the treatment of a variety of thromboembolic disorders such as atrial fibrillation and thrombosis or embolism. It inhibits fibrin production preventing clot formation. [...]
2018 - 10.1016/j.bios.2018.08.011
Biosensors & bioelectronics, Vol. 119 (November 2018) , p. 149-155  
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60.
9 p, 547.3 KB Grating couplers integrated on Mach-Zehnder interferometric biosensors operating in the visible range / Duval, Daphné (Institut Català de Nanociència i Nanotecnologia) ; Osmond, Johann (Institute of Photonic Sciences) ; Dante, Stefania (Institut Català de Nanociència i Nanotecnologia) ; Dominguez, Carlos (Institut de Microelectrònica de Barcelona) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
We present the design, fabrication, and characterization of submicronic grating couplers integrated on SiN rib waveguide Mach-Zehnder interferometers (MZIs) for biosensing applications working in the visible spectral range for both TE and TM polarizations. [...]
2013 - 10.1109/JPHOT.2013.2251873
IEEE photonics journal, Vol. 5, Issue 2 (April 2013) , art. 6476622  
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61.
11 p, 910.6 KB Nanophotonic lab-on-a-chip platforms including novel bimodal interferometers, microfluidics and grating couplers / Duval, Daphné (Institut Català de Nanociència i Nanotecnologia) ; González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia) ; Dante, Stefania (Institut Català de Nanociència i Nanotecnologia) ; Osmond, Johann (Institute of Photonic Sciences) ; Monge, Rosa (Universidad de Zaragoza) ; Fernández, Luis J. (Universidad de Zaragoza) ; Zinoviev, K. E. (Microelectronics National Center) ; Dominguez, Carlos (Microelectronics National Center) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
One of the main limitations for achieving truly lab-on-a-chip (LOC) devices for point-of-care diagnosis is the incorporation of the "on-chip" detection. Indeed, most of the state-of-the-art LOC devices usually require complex read-out instrumentation, losing the main advantages of portability and simplicity. [...]
2012 - 10.1039/c2lc40054e
Lab on a chip, Vol. 12, Issue 11 (May 2012) , p. 1987-1994  
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62.
7 p, 288.5 KB Integrated bimodal waveguide interferometric biosensor for label-free analysis / Zinoviev, K. E. (Institut de Microelectrònica de Barcelona) ; González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia) ; Dominguez, Carlos (Institut de Microelectrònica de Barcelona) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
The performance of an interferometric device based on integrated Bimodal Waveguides (BiMW) for sensing is demonstrated. The sensors are fabricated using standard silicon technology and can achieve a detection limit of 2. [...]
2011 - 10.1109/JLT.2011.2150734
Journal of lightwave technology, Vol. 29, Issue 13 (July 2011) , p. 1926-1930  
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63.
27 p, 1.1 MB Early sepsis diagnosis via protein and miRNA biomarkers using a novel point-of-care photonic biosensor / Fabri Faja, Nuria (Institut Català de Nanociència i Nanotecnologia) ; Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ; Dey, Priyanka (Institut Català de Nanociència i Nanotecnologia) ; Terborg, Roland A. (Institut de Ciències Fotòniques) ; Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ; Belushkin, Alexander (École Polytechnique Fédérale de Lausanne) ; Yesilköy, Filiz (École Polytechnique Fédérale de Lausanne) ; Duempelmann, Luc (Institut de Ciències Fotòniques) ; Altug, Hatice (École Polytechnique Fédérale de Lausanne) ; Pruneri, Valerio (Institució Catalana de Recerca i Estudis Avançats) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Sepsis is a condition characterized by a severe stage of blood-infection often leading to tissue damage, organ failure and finally death. Fast diagnosis and identification of the sepsis stage (sepsis, severe sepsis or septic shock) is critical for the patient's evolution and could help in defining the most adequate treatment in order to reduce its mortality. [...]
2019 - 10.1016/j.aca.2019.05.038
Analytica chimica acta, Vol. 1077 (October 2019) , p. 232-242  
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64.
17 p, 952.5 KB Trends in photonic lab-on-chip interferometric biosensors for point-of-care diagnostics / González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia) ; Maldonado, Jesús (Institut Català de Nanociència i Nanotecnologia) ; Herranz, Sonia (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Portable point-of care (POC) devices for in vitro diagnostics will be a milestone for the achievement of universal healthcare and environmental protection. The main goal is to reach a rapid, user-friendly and highly sensitive portable tool which can provide immediate results in any place at any time while having a competitive cost. [...]
2016 - 10.1039/c6ay02972h
Analytical methods, Vol. 8, Issue 48 (December 2016) , p. 8380-8394  
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65.
9 p, 1.1 MB A low-cost integrated biosensing platform based on SiN nanophotonics for biomarker detection in urine / Martens, Daan (Ghent University) ; Ramirez Priego, Patricia (Institut Català de Nanociència i Nanotecnologia) ; Murib, M. S. (Ghent University) ; Elamin, Ayssar A. (LIONEX Diagnostics and Therapeutics GmbH) ; González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia) ; Stehr, M. (LIONEX Diagnostics and Therapeutics GmbH) ; Jonas, F. (LIONEX Diagnostics and Therapeutics GmbH) ; Anton, Birgit (Microfluidic ChipShop GmbH) ; Hlawatsch, N. (Microfluidic ChipShop GmbH) ; Soetaert, Pieterjan (Trinean NV) ; Vos, Rita (Imec) ; Stassen, A. (Imec) ; Severi, S. (Imec) ; Van Roy, Wim (Imec) ; Bockstaele, Ronny (Trinean NV) ; Becker, Holger (Microfluidic ChipShop GmbH) ; Singh, Mahavir (LIONEX Diagnostics and Therapeutics GmbH) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia) ; Bienstman, Peter (Ghent University)
We present a low-cost integrated nanophotonic lab-on-a-chip platform suitable for point-of-care (POC) biomarker analysis. The sensor chip included in the platform contains multiplexed Mach-Zehnder interferometers with an on-chip optical spectral analyser consisting of an arrayed-waveguide grating. [...]
2018 - 10.1039/c8ay00666k
Analytical methods, Vol. 10, Issue 25 (July 2018) , p. 3066-3073
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66.
10 p, 1.1 MB Label-Free and Real-Time Detection of Tuberculosis in Human Urine Samples Using a Nanophotonic Point-of-Care Platform / Ramirez Priego, Patricia (Institut Català de Nanociència i Nanotecnologia) ; Martens, Daan (Ghent University) ; Elamin, Ayssar A. (LIONEX Diagnostics and Therapeutics GmbH) ; Soetaert, Pieterjan (Trinean NV) ; Van Roy, Wim (Imec) ; Vos, Rita (Imec) ; Anton, Birgit (Microfluidic ChipShop GmbH) ; Bockstaele, Ronny (Trinean NV) ; Becker, Holger (Microfluidic ChipShop GmbH) ; Singh, Mahavir (LIONEX Diagnostics and Therapeutics GmbH) ; Bienstman, Peter (Ghent University) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Tuberculosis (TB) is the leading global cause of death from a single infectious agent. Registered incidence rates are low, especially in low-resource countries with weak health systems, due to the disadvantages of current diagnostic techniques. [...]
2018 - 10.1021/acssensors.8b00393
ACS Sensors, Vol. 3, Núm. 10 (September 2018) , p. 2079-2086  
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67.
17 p, 188.9 KB Design of a surface plasmon resonance immunoassay for therapeutic drug monitoring of amikacin / Losoya Leal, Adrián (Tecnológico de Monterrey) ; Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ; Martínez Chapa, Sergio O. (Tecnológico de Monterrey) ; Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
The therapeutic drug monitoring (TDM) of pharmaceutical drugs with narrow therapeutic ranges is of great importance in the clinical setting. It provides useful information towards the enhancement of drug therapies, aiding in dosage control and toxicity risk management. [...]
2015 - 10.1016/j.talanta.2015.04.009
Talanta, Vol. 141 (August 2015) , p. 253-258  
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Articles : 84 records found   beginprevious58 - 67nextend  jump to record:
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3 Lechuga, L. M.
91 Lechuga, Laura M
14 Lechuga, Laura M,
3 Lechuga, Laura M.
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