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9 p, 544.7 KB |
Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir/Abacavir/Lamivudine in Antiretroviral-Naive Adults (SYMTRI) : A Multicenter Randomized Open-Label Study (PReEC/RIS-57)
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Podzamczer, Daniel (Hospital Universitari de Bellvitge) ;
Micán, R. (Hospital Universitario La Paz (Madrid)) ;
Tiraboschi, Juan Manuel (Hospital Universitari de Bellvitge) ;
Portilla, J. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Llibre, Josep M.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ribera, E. (Hospital Universitari Vall d'Hebron) ;
Vivancos, M.J. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Morano, L. (Hospital Álvaro Cunqueiro (Vigo)) ;
Masiá, M. (Hospital General Universitario de Elche) ;
Gómez, C. (Hospital Universitario Virgen de la Victoria-IBIMA) ;
Fanjul, F. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Payeras, A. (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Inciarte, Alexy (Hospital Clínic i Provincial de Barcelona) ;
Estrada, V. (Hospital Clínico San Carlos-IdiSSC) ;
Rivero, A. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Castro, A. (Complejo Hospitalario Universitario) ;
Bernal, Enrique (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Vinuesa, D. (Hospital Universitario San Cecilio (Granada)) ;
Knobel Freud, Hernando (Hospital del Mar (Barcelona, Catalunya)) ;
Troya, J. (Hospital Universitario Infanta Leonor) ;
Macías, Juan (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Montero, M. (Hospital Universitari i Politècnic La Fe (València)) ;
Sanz, J. (Hospital Universitario de la Princesa (Madrid)) ;
Navarro-Alcaraz, Antonio (Hospital Universitari de Bellvitge) ;
Caicedo, A. (Ris Red de Investigación en Sida) ;
Fernández, G. (Hospital Universitari de Bellvitge) ;
Martínez, Esteban (Hospital Clínic i Provincial de Barcelona) ;
Moreno, S. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Universitat Autònoma de Barcelona
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) is the reference for combination therapy based on protease inhibitors due to its efficacy, tolerability, and convenience. Head-to-head randomized comparisons between D/C/F/TAF and combination therapy based on integrase inhibitors in antiretroviral-naive patients are lacking. [...]
2022 -  10.1093/ofid/ofab595
Open Forum Infectious Diseases, Vol. 9 Núm. 3 (january 2022) , p. ofab595
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21 p, 11.5 MB |
Identification of constrained sequence elements across 239 primate genomes
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Kuderna, Lukas F. K. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ulirsch, Jacob C. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Rashid, Sabrina (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ameen, Mohamed (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Sundaram, Laksshman (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Hickey, Glenn (University of California. Santa Cruz Genomics Institute) ;
Cox, Anthony J. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Gao, Hong (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Kumar, Arvind (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Aguet, Francois (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Christmas, Matthew J. (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Clawson, Hiram (University of California. Santa Cruz Genomics Institute) ;
Haeussler, Maximilian (University of California. Santa Cruz Genomics Institu) ;
Janiak, Mareike C. (University of Salford. School of Science, Engineering and Environment) ;
Kuhlwilm, Martin (University of Vienna. Department of Evolutionary Anthropology) ;
Orkin, Joseph D. (Université de Montréal. Département d'Anthropologie) ;
Bataillon, Thomas (Aarhus University. Bioinformatics Research Centre) ;
Shivakumara Manu (Academy of Scientific and Innovative Research (Ghaziabad, Índia)) ;
Valenzuela, Alejandro (Institut de Biologia Evolutiva (Barcelona)) ;
Bergman, Juraj (Aarhus University. Bioinformatics Research Centre) ;
Rouselle, Marjolaine (Aarhus University. Bioinformatics Research Centre) ;
Silva, Felipe Ennes (Mamirauá Institute for Sustainable Development) ;
Agueda Calpena, Lidia (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Blanc, Julie (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Gut, Marta (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
de Vries, Dorien (University of Salford. School of Science, Engineering and Environment) ;
Goodhead, Ian (University of Salford. School of Science, Engineering and Environment) ;
Harris, R. Alan (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Raveendran, Muthuswamy (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Jensen, Axel (Uppsala University. Department of Ecology and Genetics) ;
Chuma, Idriss S. (Tanzania National Parks) ;
Horvath, Julie E. (University of North Carolina at Chapel Hill. Renaissance Computing Institute) ;
Hvilsom, Christina (Copenhagen Zoo) ;
Juan, David (Institut de Biologia Evolutiva (Barcelona)) ;
Frandsen, Peter (Copenhagen Zoo) ;
Schraiber, Joshua G. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
de Melo, Fabiano R. (Universidade Federal de Viçosa) ;
Bertuol, Fabrício (Universidade Federal do Amazonas. Departamento de Genética) ;
Byrne, Hazel (University of Utah. Department of Anthropology) ;
Sampaio, Iracilda (Universidade Federal do Pará (Brasil)) ;
Pires Farias, Izeni (Universidade Federal do Amazonas. Departamento de Genética) ;
Valsecchi, João (Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica-ComFauna) ;
Messias, Malu (Universidade Federal de Rondônia) ;
da Silva, Maria N. F. (Instituto Nacional de Pesquisas da Amazônia) ;
Trivedi, Mihir (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Rossi, Rogerio (Universidade Federal do Mato Grosso. Instituto de Biociências) ;
Hrbek, Tomas (Trinity University. Department of Biology) ;
Andriaholinirina, Nicole (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Rabarivola, Clément J. (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Zaramody, Alphonse (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Jolly, Clifford J. (New York University .Department of Anthropology) ;
Phillips-Conroy, Jane (Washington University School of Medicine in St Louis. Department of Neuroscience) ;
Wilkerson, Gregory (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Abbee, C. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Simmons, Joe H. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Fernandez-Duque, Eduardo (Yale University. Department of Anthropology) ;
Kanthaswamy, Sree (University of California. California National Primate Research Center) ;
Shiferaw, Fekadu (The Carter Center Ethiopia) ;
Wu, Dong-Dong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhou, Long (Zhejiang University School of Medicine. Center for Evolutionary and Organismal Biology) ;
Shao, Yong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhang, Guojie (Zhejiang University Medical Center) ;
Keyyu, Julius D. (Tanzania Wildlife Research Institute) ;
Knauf, Sascha (Justus Liebig University. Faculty of Veterinary Medicine) ;
Le, Minh D. (Vietnam National University. Department of Environmental Ecology) ;
Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont) ;
Merker, Stefan epartment of Environmental Ecology (State Museum of Natural History Stuttgart. Department of Zoology) ;
Navarro, Arcadi, 1969- (Institut de Biologia Evolutiva (Barcelona)) ;
Nadler, Tilo (Cuc Phuong Commune) ;
Khor, Chiea Chuen (Genome Institute of Singapore) ;
Lee, Jessica (Mandai Nature) ;
Tan, Patrick (Duke-NUS Medical School) ;
Lim, Weng Khong (SingHealth Duke-NUS Genomic Medicine Centre) ;
Kitchener, Andrew C. (School of Geosciences) ;
Zinner, Dietmar (Leibniz ScienceCampus Primate Cognition) ;
Gut, Ivo (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Melin, Amanda D. (University of Calgary. Alberta Children's Hospital Research Institute) ;
Guschanski, Katerina (University of Edinburgh. School of Biological Sciences) ;
Schierup, Mikkel Heide (Aarhus University. Bioinformatics Research Centre) ;
Beck, Robin (University of Salford. School of Science, Engineering and Environment) ;
Karakikes, Ioannis (Stanford University. Department of Cardiothoracic Surgery) ;
Wang, Kevin C. (Veterans Affairs Palo Alto Healthcare System) ;
Umapathy, Govindhaswamy (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Roos, Christian (Leibniz Institute for Primate Research. German Primate Center) ;
Boubli, Jean (University of Salford. School of Science, Engineering and Environment) ;
Siepel, Adam (Simons Center for Quantitative Biology. Cold Spring Harbor Laboratory) ;
Kundaje, Anshul (Stanford University. Department of Genetics) ;
Paten, Benedict (University of California. Santa Cruz Genomics Institute) ;
Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Rogers, Jeffrey (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Farh, Kyle Kai-How (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units))
Noncoding DNA is central to our understanding of human gene regulation and complex diseases and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome. [...]
2023 - 10.1038/s41586-023-06798-8
Nature, Published online nov. 2023
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13.
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11 p, 2.0 MB |
Development of a Novel Anti-CD19 Chimeric Antigen Receptor : A Paradigm for an Affordable CAR T Cell Production at Academic Institutions
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Castella, Maria (Hospital Clínic i Provincial de Barcelona) ;
Boronat, Anna (Hospital Clínic i Provincial de Barcelona) ;
Martín-Ibáñez, Raquel (Universitat de Barcelona) ;
Rodríguez, Vanina (Institut d'Investigacions Biomèdiques August Pi i Sunyer - IDIBAPS) ;
Suñé, Guillermo (Hospital Clínic i Provincial de Barcelona) ;
Caballero, Miguel (Hospital Clínic i Provincial de Barcelona) ;
Marzal, Berta (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Amill, Lorena (Hospital Clínic i Provincial de Barcelona) ;
Martín-Antonio, B. (Hospital Clínic i Provincial de Barcelona) ;
Castaño Cardoso, Julio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Balagué, Olga (Hospital Clínic i Provincial de Barcelona) ;
González-Navarro, Europa Azucena (Hospital Clínic i Provincial de Barcelona) ;
Serra-Pages, Carles (Hospital Clínic i Provincial de Barcelona) ;
Engel, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Vilella, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Benítez Ribas, Daniel (Hospital Clínic i Provincial de Barcelona) ;
Ortiz-Maldonado, Valentín (Hospital Clínic i Provincial de Barcelona) ;
Cid, Joan (Hospital Clínic i Provincial de Barcelona) ;
Tabera, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Canals, Josep M. (Universitat de Barcelona) ;
Lozano, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Baumann, Tycho (Hospital Clínic i Provincial de Barcelona) ;
Vilarrodona, Anna (Institut d'Investigació Biomèdica Sant Pau) ;
Trias, Esteve (Hospital Clínic i Provincial de Barcelona) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Urbano-Ispizua, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Yagüe, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Galán, Patricia (Centro de Investigación Biomédica en Red de Cáncer) ;
Rives, Susana (Institut de Recerca Sant Joan de Déu) ;
Delgado, Julio (Hospital Clínic i Provincial de Barcelona) ;
Juan, Manel (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Genetically modifying autologous T cells to express an anti-CD19 chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19+ B cell malignancies in several clinical trials (CTs). [...]
2019 - 10.1016/j.omtm.2018.11.010
Molecular Therapy. Methods & Clinical Development, Vol. 12 (15 2019) , p. 134-144
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14 p, 1.3 MB |
Prevention of HIV and other sexually transmitted infections by geofencing and contextualized messages with a gamified APP, UBESAFE : Design and creation study
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Besoain, F. (Universitat Oberta de Catalunya) ;
Perez-Navarro, A. (Universitat Oberta de Catalunya) ;
Jacques-Aviñó, Constanza (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Caylà, Joan A (Fundació de la Unitat d'Investigació en Tuberculosi de Barcelona) ;
Barriga, N.A. (Universidad de Talca) ;
García de Olalla, Patricia (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Advances in the development of information and communication technologies have facilitated social and sexual interrelationships, thanks to the websites and apps created to this end. However, these resources can also encourage sexual contacts without appropriate preventive measures in relation to HIV and other sexually transmitted infections (STIs). [...]
2020 - 10.2196/14568
JMIR mHealth and uHealth, Vol. 8 Núm. 3 (2020) , p. e14568
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15.
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16.
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5 p, 2.1 MB |
RecruitNet: A global database of plant recruitment networks
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Verdú, Miguel (Centro de Investigaciones Sobre Desertificación) ;
Garrido, José Luis (Estación Biológica de Doñana) ;
Alcántara, Julio M. (Andalusian Institute for Earth System Research) ;
Montesinos-Navarro, Alicia (Centro de Investigaciones Sobre Desertificación) ;
Aguilar, Salomón (Smithsonian Tropical Research Institute) ;
Aizen, Marcelo A. (Universidad Nacional del Comahue-CONICET) ;
Al-Namazi, Ali A. (King Abdulaziz City for Science and Technology) ;
Alifriqui, Mohamed (Cadi Ayyad University) ;
Allen, David (Middlebury College) ;
Anderson-Teixeira, Kristina J. (Smithsonian National Zoo and Conservation Biology Institute) ;
Armas, Cristina (Estación Experimental de Zonas Áridas) ;
Bastida, Jesús M. (Consejo Superior de Investigaciones Científicas) ;
Bellido, Tono (SVivers Municipals de El Saler) ;
Bonanomi, Giuliano (University of Naples Federico II) ;
Paterno, Gustavo B. (University of Göttingen) ;
Briceño, Herbert (Estación Experimental de Zonas Áridas) ;
de Oliveira, Ricardo A. C. (Universidade Federal do Paraná) ;
Campoy, Josefina G. (Universidade de Santiago de Compostela) ;
Chaieb, Ghassen (University of Bordeaux) ;
Chu, Chengjin (Sun Yat-sen University) ;
Collins, Sarah E. (Centro de Investigaciones Sobre Desertificación) ;
Condit, Richard (University of California) ;
Constantinou, Elena (Open University of Cyprus) ;
Degirmenci, Cihan Ü. (Hacettepe University) ;
Delalandre, Leo (University of Montpellier) ;
Duarte, Milen (Instituto de Ecología y Biodiversidad) ;
Faife, Michel (Universidad Central 'Marta Abreu' de Las Villas) ;
Fazlioglu, Fatih (Bayreuth University) ;
Fernando, Edwino S. (University of the Philippines) ;
Flores, Joel (Instituto Potosino de Investigación Científica y Tecnológica) ;
Flores-Olvera, Hilda (Universidad Nacional Autónoma de México) ;
Fodor, Ecaterina (University of Oradea) ;
Ganade, Gislene (Universidade Federal do Rio Grande do Norte) ;
Garcia, María Begoña (Pyrenean Institute of Ecology) ;
García-Fayos, Patricio (Centro de Investigaciones Sobre Desertificación) ;
Gavini, Sabrina S. (Universidad Nacional del Comahue-CONICET) ;
Goberna, Marta (Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria) ;
Gómez-Aparicio, Lorena (Consejo Superior de Investigaciones Científicas) ;
González-Pendás, Enrique (Centro de Investigaciones y Servicios Ambientales) ;
González-Robles, Ana (Universidad de Jaén) ;
Hubbell, Stephen P. (University of California) ;
İpekdal, Kahraman (Ahi Evran University) ;
Jorquera, María J. (Estación Experimental de Zonas Áridas) ;
Kikvidze, Zaal (Ilia State University) ;
Kütküt, Pınar (Hacettepe University) ;
Ledo, Alicia (Freelance Scientist) ;
Lendínez, Sandra (Estación Experimental del Zaidín) ;
Li, Buhang (Sun Yat-sen University) ;
Liu, Hanlun (Sun Yat-sen University) ;
Lloret Maya, Francisco (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
López, Ramiro P. (Facultad de Ciencias Puras y Naturales) ;
López-García, Álvaro (Estación Experimental del Zaidín) ;
Lortie, Christopher J. (York University) ;
Losapio, Gianalberto (University of Lausanne) ;
Lutz, James A. (Utah State University) ;
Luzuriaga, Arantzazu L. (Rey Juan Carlos University) ;
Máliš, František (Technical University in Zvolen) ;
Manrique, Esteban (Real Jardín Botánico) ;
Manzaneda, Antonio J. (Universidad de Jaén) ;
Marcilio-Silva, Vinicius (University of Minnesota) ;
Michalet, Richard (University of Bordeaux) ;
Molina-Venegas, Rafael (Universidad de Alcalá) ;
Navarro-Cano, José Antonio (Centro Nacional Instituto de Investigación y Tecnología Agraria y Alimentaria) ;
Novotny, Vojtech (Czech Academy of Sciences) ;
Olesen, Jens M. (Aarhus University) ;
Ortiz-Brunel, Juan P. (Universidad de Guadalajara) ;
Pajares-Murgó, María (Universidad de Jaén) ;
Parissis, Nikolas (Democritus University of Thrace) ;
Parker, Geoffrey (Smithsonian Environmental Research Center) ;
Perea, Antonio J. (Universidad de Jaén) ;
Pérez-Hernández, Vidal (Centro de Investigaciones y Servicios Ambientales) ;
Pérez-Navarro, María Ángeles (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Pistón, Nuria (Universidade Federal do Rio de Janeiro) ;
Pizarro-Carbonell, Elisa (Asociación Aprisco) ;
Prieto, Iván (University of León) ;
Prieto-Rubio, Jorge (Estación Experimental del Zaidín) ;
Pugnaire, Francisco I. (Estación Experimental de Zonas Áridas) ;
Ramírez, Nelson (Universidad Central de Venezuela) ;
Retuerto, Rubén (Universidade de Santiago de Compostela) ;
Rey, Pedro J. (Andalusian Institute for Earth System Research () ;
Rodriguez Ginart, Daniel A. (Centro de Investigaciones Sobre Desertificación) ;
Rodríguez-Sánchez, Mariana (Universidad Nacional Autónoma de México) ;
Sánchez-Martín, Ricardo (Centro de Investigaciones Sobre Desertificación) ;
Schöb, Christian (Institute of Agricultural Sciences) ;
Tavşanoğlu, Çağatay (Hacettepe University) ;
Tedoradze, Giorgi (Ilia State University) ;
Tercero-Araque, Amanda (Universidad de Jaén) ;
Tielbörger, Katja (University of Tübingen) ;
Touzard, Blaise (Sun Yat-sen University) ;
Tüfekcioğlu, İrem (University of Montpellier) ;
Turkis, Sevda (Ordu University) ;
Usero, Francisco M. (Estación Experimental de Zonas Áridas) ;
Usta, Nurbahar (Hacettepe University) ;
Valiente-Banuet, Alfonso (Universidad Nacional Autónoma de México) ;
Vargas-Colin, Alexia (Instituto Potosino de Investigación Científica y Tecnológica) ;
Vogiatzakis, Ioannis (Open University of Cyprus) ;
Zamora Rodríguez, Regino (Universidad de Granada)
Plant recruitment interactions (i. e. , what recruits under what) shape the composition, diversity, and structure of plant communities. Despite the huge body of knowledge on the mechanisms underlying recruitment interactions among species, we still know little about the structure of the recruitment networks emerging in ecological communities. [...]
2023 - 10.1002/ecy.3923
Ecology, Vol. 104, Num. 2 (January 2023) , art. e3923
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29 p, 2.1 MB |
Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome
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Navarro-Romero, Alba (Universitat Pompeu Fabra) ;
Galera-López, Lorena (Universitat Pompeu Fabra) ;
Ortiz-Romero, Paula (Universitat de Barcelona) ;
Llorente-Ovejero, Alberto (UPV Leioa) ;
de los Reyes-Ramírez, Lucía (Universitat Pompeu Fabra) ;
Bengoetxea de Tena, Iker (UPV Leioa) ;
Garcia-Elias, Anna (Universitat Pompeu Fabra) ;
Mas-Stachurska, Aleksandra (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Reixachs-Solé, Marina ;
Pastor, Antoni (Institut Hospital del Mar d'Investigacions Mèdiques) ;
De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Maldonado, Rafael 1961- (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Benito, Begoña (Hospital Universitari Vall d'Hebron) ;
Eyras, Eduardo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodríguez-Puertas, Rafael (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Campuzano, Victoria (Universitat de Barcelona) ;
Ozaita, Andres (Universitat Pompeu Fabra) ;
Universitat Autònoma de Barcelona
Williams-Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular abnormalities. [...]
2022 - 10.7554/eLife.72560
eLife, Vol. 11 (october 2022)
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18.
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15 p, 2.7 MB |
Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology
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Navarro, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fernández González, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Riera del Brio, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montpeyó Garcia-Moreno, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lopez-Royo, Tresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castillo-Sanchez, Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carnicer-Cáceres, Clara (Institució Catalana de Recerca i Estudis Avançats) ;
Arranz-Amo, Jose Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pradas-Gracia, Eddie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casas, Josefina (Institut de Química Avançada de Catalunya) ;
Vila Bover, Miquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez-Vicente, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Mutations in the GBA gene that encodes the lysosomal enzyme β-glucocerebrosidase (GCase) are a major genetic risk factor for Parkinson's disease (PD). In this study, we generated a set of differentiated and stable human dopaminergic cell lines that express the two most prevalent GBA mutations as well as GBA knockout cell lines as a in vitro disease modeling system to study the relationship between mutant GBA and the abnormal accumulation of α-synuclein. [...]
2022 - 10.1038/s41531-022-00397-6
NPJ Parkinson's disease, Vol. 8 (october 2022)
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11 p, 3.2 MB |
Study of Excipients in Delayed Skin Reactions to mRNA Vaccines : Positive Delayed Intradermal Reactions to Polyethylene Glycol Provide New Insights for COVID-19 Arm
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Pesqué, David (Hospital del Mar (Barcelona, Catalunya)) ;
Pujol Vallverdú, Ramón M (Hospital del Mar (Barcelona, Catalunya)) ;
Marcantonio Santa Cruz, Orianna Yilsy (Hospital del Mar (Barcelona, Catalunya)) ;
Vidal-Navarro, Ainhoa (Hospital del Mar (Barcelona, Catalunya)) ;
Ramada Rodilla, José María (Hospital del Mar (Barcelona, Catalunya)) ;
Arderiu-Formentí, Alba (Hospital del Mar (Barcelona, Catalunya)) ;
Albalat-Torres, Agustí (Hospital del Mar (Barcelona, Catalunya)) ;
Serra, Consol (Hospital del Mar (Barcelona, Catalunya)) ;
Giménez-Arnau, Ana M 1961- (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Background: Skin local reactions to mRNA COVID-19 vaccines have been linked to the use of vaccine excipients. The aim of the study is to evaluate the role of skin testing excipients in delayed skin reactions due to mRNA COVID-19 vaccines. [...]
2022 - 10.3390/vaccines10122048
Vaccines (Basel), Vol. 10 (november 2022)
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Dynamic changes in circulating tumor assessed by shallow whole-genome sequencing associate with clinical efficacy of checkpoint inhibitors in
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Carbonell, Caterina (Vall d'Hebron Institut d'Oncologia) ;
Frigola Rissech, Joan (Vall d'Hebron Institut d'Oncologia) ;
Pardo Aranda, Nuria (Vall d'Hebron Institut d'Oncologia) ;
Callejo, Ana (Vall d'Hebron Institut d'Oncologia) ;
Iranzo, Patricia (Vall d'Hebron Institut d'Oncologia) ;
Valdivia, Augusto (Vall d'Hebron Institut d'Oncologia) ;
Priano, Ilaria (Vall d'Hebron Institut d'Oncologia) ;
Cedrés, Susana (Vall d'Hebron Institut d'Oncologia) ;
Martinez-Marti, Alex (Vall d'Hebron Institut d'Oncologia) ;
Navarro, Alejandro (Vall d'Hebron Institut d'Oncologia) ;
Lenza, Laura (Vall d'Hebron Institut d'Oncologia) ;
Soleda, Mireia (Vall d'Hebron Institut d'Oncologia) ;
Gonzalo-Ruiz, Javier (Vall d'Hebron Institut d'Oncologia) ;
Vivancos, Ana (Vall d'Hebron Institut d'Oncologia) ;
Sansó, Miriam (Institut d'Investigació Sanitària Illes Balears) ;
Carcereny, Enric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Amat, Ramon (Vall d'Hebron Institut d'Oncologia) ;
Felip, Enriqueta (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis are the main therapeutic option for patients with advanced non-small cell lung cancer (NSCLC) without a druggable oncogenic alteration. [...]
2023 - 10.1002/1878-0261.13409
Molecular Oncology, Vol. 17 (march 2023) , p. 779-791
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