Artículos


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Artículos Encontrados 749 registros  inicioanterior21 - 30siguientefinal  ir al registro: La búsqueda tardó 0.01 segundos. 
21.
50 p, 28.5 MB Pan-cancer proteogenomics connects oncogenic drivers to functional states / Li, Yize (Washington University in St. Louis) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Tokheim, Collin (Harvard T.H. Chan School of Public Health) ; Bailey, Matthew H. (Brigham Young University) ; Yaron, Tomer (Weill Cornell Medicine) ; Stathias, Vasileios (University of Miami Miller School of Medicine) ; Geffen, Yifat (Massachusetts General Hospital) ; Imbach, Kathleen (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Cao, Song (McDonnell Genome Institute) ; Anand, Shankara (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Akiyama, Yo (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Liu, Wenke (NYU Grossman School of Medicine) ; Wyczalkowski, Matthew A. (McDonnell Genome Institute) ; Song, Yizhe (McDonnell Genome Institute) ; Storrs, Erik P. (McDonnell Genome Institute) ; Wendl, Michael C. (Washington University in St. Louis) ; Zhang, Wubing (Dana-Farber Cancer Institute (Boston, Estats Units)) ; Sibai, Mustafa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ruiz-Serra, Victoria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Liang, Wen-Wei (McDonnell Genome Institute) ; Terekhanova, Nadezhda V. (McDonnell Genome Institute) ; Martins Rodrigues, Fernanda (McDonnell Genome Institute) ; Clauser, Karl R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Heiman, David I. (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Zhang, Qing (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Aguet, Francois (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Calinawan, Anna Pamela (Icahn School of Medicine at Mount Sinai) ; Dhanasekaran, Saravana Mohan (University of Michigan) ; Birger, Chet (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Satpathy, Shankha (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Zhou, Daniel Cui (McDonnell Genome Institute) ; Wang, Liang-Bo (McDonnell Genome Institute) ; Baral, Jessika (McDonnell Genome Institute) ; Johnson, Jared L. (Weill Cornell Medicine) ; Huntsman, Emily M. (Weill Cornell Medicine) ; Pugliese, Pietro (University of Sannio (Benevento, Itàlia)) ; Colaprico, Antonio (University of Miami Miller School of Medicine) ; Iavarone, Antonio (University of Miami Miller School of Medicine) ; Chheda, Milan G. (Washington University in St. Louis) ; Ricketts, Christopher J. (National Institutes of Health) ; Fenyö, David (NYU Grossman School of Medicine) ; Payne, Samuel H. (Brigham Young University) ; Rodriguez, Henry (Office of Cancer Clinical Proteomics Research) ; Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ; Gillette, Michael A. (Harvard Medical School) ; Kumar-Sinha, Chandan (University of Michigan) ; Lazar, Alexander (The University of Texas MD Anderson Cancer Center) ; Cantley, Lewis (Weill Cornell Medicine) ; Getz, Gad A. (Harvard Medical School) ; Ding, Li (Siteman Cancer Center) ; An, Eunkyung ; Anurag, Meenakshi ; Bavarva, Jasmin ; Birrer, Michael J. ; Ceccarelli, Michele ; Chan, Daniel W. ; Chinnaiyan, Arul M. ; Cho, Hanbyul ; Chowdhury, Shrabanti ; Cieslik, Marcin P. ; da Veiga Leprevost, Felipe ; Day, Corbin ; Domagalski, Marcin J. ; Dou, Yongchao ; Druker, Brian J. ; Edwards, Nathan ; Ellis, Matthew J. ; Selvan, Myvizhi Esai ; Foltz, Steven M. ; Francis, Alicia ; Gonzalez Robles, Tania J. ; Gosline, Sara J. C. ; Gümüş, Zeynep H. ; Hiltke, Tara ; Hong, Runyu ; Hostetter, Galen ; Hu, Yingwei ; Huang, Chen ; Huntsman, Emily ; Jaehnig, Eric J. ; Jewel, Scott D. ; Ji, Jiayi ; Jiang, Wen ; Katsnelson, Lizabeth ; Ketchum, Karen A. ; Kolodziejczak, Iga ; Lei, Jonathan T. ; Liao, Yuxing ; Lindgren, Caleb M. ; Liu, Tao ; Ma, Weiping ; McKerrow, Wilson ; Nesvizhskii, Alexey I. ; Newton, Chelsea ; Oldroyd, Robert ; Omenn, Gilbert S. ; Paulovich, Amanda G. ; Petralia, Francesca ; Reva, Boris ; Rodland, Karin D. ; Ruggles, Kelly V. ; Rykunov, Dmitry ; Savage, Sara R. ; Schadt, Eric E. ; Schnaubelt, Michael ; Schraink, Tobias ; Shi, Zhiao ; Smith, Richard D. ; Song, Xiaoyu ; Tan, Jimin ; Thangudu, Ratna R. ; Tignor, Nicole ; Wang, Joshua M. ; Wang, Pei ; Wang, Ying Cindy ; Wen, Bo ; Wiznerowicz, Maciej ; Yi, Xinpei ; Zhang, Bing ; Zhang, Hui ; Zhang, Xu ; Zhang, Zhen ; Universitat Autònoma de Barcelona
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-cancer analysis uncovers insights into the impacts of cancer drivers by identifying their significant cis-effects and distal trans-effects quantified at the RNA, protein, and phosphoprotein levels. [...]
2023 - 10.1016/j.cell.2023.07.014
Cell, Vol. 186 Núm. 18 (31 2023) , p. 3921-3944.e25  
22.
8 p, 1.2 MB AXL - a new player in resistance to HER2 blockade / Adam-Artigues, Anna (INCLIVA Biomedical Research Institute) ; Arenas, Enrique J (Centro de Investigación Biomédica en Red de Cáncer) ; Arribas, Joaquín V (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Prat, Aleix (SOLTI Breast Cancer Research Group) ; Cejalvo, Juan Miguel (Vall d'Hebron Institut d'Oncologia)
HER2 is a driver in solid tumors, mainly breast, oesophageal and gastric cancer, through activation of oncogenic signaling pathways such as PI3K or MAPK. HER2 overexpression associates with aggressive disease and poor prognosis. [...]
2023 - 10.1016/j.ctrv.2023.102639
Cancer Treatment Reviews, Vol. 121 (december 2023) , p. 102639  
23.
11 p, 310.2 KB Time trends and survival of marginal zone lymphoma over 25 years in Girona, Spain (1994-2018) / Auñón, Carmen (Universitat de Girona. Departament de Medicina) ; Sanvisens, Arantza (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Turon, Estel (Institut d'Investigació Biomèdica de Girona) ; Vidal Vila, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Puigdemont, Montse (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Osca Gelis, Gemma (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Eraso, Arantxa (Universitat de Girona. Departament de Medicina) ; Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Objective: To analyze the incidence, incidence trends, and survival of marginal zone lymphomas (MZLs) in Girona and to describe these indicators based on the location in the case of extranodal MZLs. Methods: Population-based study of MZL collected in the Girona Cancer Registry, 1994-2018. [...]
2023 - 10.1002/cam4.5935
Cancer Medicine, Vol. 12 Núm. 11 (june 2023) , p. 12343-12353  
24.
19 p, 8.1 MB Formation of an invasion-permissive matrix requires TGFβ/SNAIL1-regulated alternative splicing of fibronectin / Franco Valls, Héctor (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Tusquets Uxó, Elsa (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Sala, Laura (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Val, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Peña, Raúl (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Iaconcig, Alessandra (International Centre for Genetic Engineering and Biotechnology (ICGEB)) ; Villarino, Álvaro (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Jiménez Arriola, Martín (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Massó, Pere (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Trincado Alonso, Juan Luis, 1987- (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Eyras, Eduardo (John Curtin School of Medical Research. Australian National University) ; Muro, Andrés F. (International Centre for Genetic Engineering and Biotechnology (ICGEB)) ; Otero, Jorge (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Garcia de Herreros, Antonio (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM)) ; Baulida, Josep (Programa de Recerca en Càncer. Hospital del Mar Research Institute (IMIM))
Background: As in most solid cancers, the emergence of cells with oncogenic mutations in the mammary epithelium alters the tissue homeostasis. Some soluble factors, such as TGFβ, potently modify the behavior of healthy stromal cells. [...]
2023 - 10.1186/s13058-023-01736-y
Breast cancer research, Vol. 25 Núm. 1 (december 2023) , p. 143  
25.
42 p, 1.8 MB Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics / Janin, Maxime (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Most of the cancer-associated mortality and morbidity can be attributed to metastasis. The role of epigenetic and epitranscriptomic alterations in cancer origin and progression has been extensively demonstrated during the last years. [...]
2023 - 10.1007/s10555-023-10120-3
Cancer and Metastasis Reviews, Vol. 42 Núm. 4 (december 2023) , p. 1071-1112  
26.
49 p, 3.2 MB Cancer epigenetics in clinical practice / Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Cancer development is driven by the accumulation of alterations affecting the structure and function of the genome. Whereas genetic changes disrupt the DNA sequence, epigenetic alterations contribute to the acquisition of hallmark tumor capabilities by regulating gene expression programs that promote tumorigenesis. [...]
2023 - 10.3322/caac.21765
CA Cancer Journal for Clinicians, Vol. 73 Núm. 4 (2023) , p. 376-424  
27.
13 p, 3.0 MB Defining the optimal sequence for the systemic treatment of metastatic breast cancer / Albanell Mestres, Joan (Hospital del Mar (Barcelona, Catalunya)) ; Barnadas i Molins, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Martínez, Leticia C. (Complejo Hospitalario Universitario de A Coruña) ; López-Muñiz, José Ignacio Chacón (Hospital Virgen de la Salud (Toledo)) ; Ciruelos, Eva (Hospital 12 de Octubre (Madrid)) ; de Juan Ferre, Ana (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; del Barco Berrón, S. (Institut Català d'Oncologia) ; Pérez, Y.F. (Hospital Universitario Central de Asturias) ; Mata, J.G. (Hospital Santa María Nai en Ourense) ; Palomo, A.G. (Complejo Asistencial de León) ; Gregori, J.G. (Fundació Institut Valencià d'Oncologia) ; Pardo, P.G. (Hospital Universitari Vall d'Hebron) ; Mañas, J.J.I. (Complejo Hospitalario de Navarra) ; Hernández, A.L. (Hospital Clínic Universitari (València)) ; de Dueñas, E.M. (Consorci Hospitalari Provincial de Castelló) ; Jáñez, N.M. (Hospital Universitario Ramón y Cajal (Madrid)) ; Murillo, S.M. (Hospital Universitari Arnau de Vilanova) ; Bofill, J.S. (Hospital Universitario Nuestra Señora de Valme) ; Auñón, P.Z. (Hospital Universitario La Paz (Madrid)) ; Sanchez-Rovira, P. (Complejo Hospitalario de Jaén) ; Universitat Autònoma de Barcelona
Metastatic breast cancer is a heterogeneous disease that presents in varying forms, and a growing number of therapeutic options makes it difficult to determine the best choice in each particular situation. [...]
2017 - 10.1007/s12094-016-1520-2
Clinical & Translational Oncology, Vol. 19 Núm. 2 (january 2017) , p. 149-161  
28.
6 p, 255.0 KB Cumulative risk of breast cancer screening outcomes according to the presence of previous benign breast disease and family history of breast cancer : Supporting personalised screening / Román, M. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Quintana Ruiz, Maria Jesús (Institut d'Investigació Biomèdica Sant Pau) ; Ferrer, J. (Parc Hospitalari Martí i Julià) ; Sala, M. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Castells, X. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Our aim was to assess the cumulative risk of false-positive screening results, screen-detected cancer, and interval breast cancer in mammography screening among women with and without a previous benign breast disease and a family history of breast cancer. [...]
2017 - 10.1038/bjc.2017.107
British Journal of Cancer, Vol. 116 Núm. 11 (23 2017) , p. 1480-1485  
29.
8 p, 508.4 KB Biomarkers expression in benign breast diseases and risk of subsequent breast cancer : a case-control study / Posso, Margarita (Institut Hospital del Mar d'Investigacions Mèdiques) ; Corominas, Josep (Institut Hospital del Mar d'Investigacions Mèdiques) ; Serrano, Laia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Román, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Torá-Rocamora, Isabel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Domingo, Laia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Romero, Anabel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Quintana, M.J. (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Vernet-Tomas, Maria (Institut Hospital del Mar d'Investigacions Mèdiques) ; Baré i Mañas, Marisa (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Vidal, Carmen (Institut Català d'Oncología) ; Sánchez, Mar (Catalunya. Generalitat) ; Saladié, Francina (Fundación Liga para la Investigación y Prevención del Cáncer (Tarragona, Catalunya)) ; Natal, Carmen (Programa de Detección de Cáncer de Mama del Principado de Asturias) ; Ferrer, Joan (Hospital de Santa Caterina (Salt, Girona)) ; Servitja, Sonia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sala, Maria (Institut Hospital del Mar d'Investigacions Mèdiques) ; Castells, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Burón, A. ; Rodríguez-Arana, A. ; Romero, A. ; Vernet, M. ; Andreu, Xavier ; Milà, N. ; López Vilaró, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Fernández-Somoano, A. ; Galceran, J. ; Espinàs, J.A. ; Universitat Autònoma de Barcelona
Women with benign breast diseases (BBD) have a high risk of breast cancer. However, no biomarkers have been clearly established to predict cancer in these women. Our aim was to explore whether estrogen receptor (ER), progesterone receptor (PR), and Ki67 expression stratify risk of breast cancer in screened women with BBD. [...]
2017 - 10.1002/cam4.1080
Cancer Medicine, Vol. 6 Núm. 6 (june 2017) , p. 1482-1489  
30.
7 p, 1.1 MB Multidisciplinary management of head and neck cancer : First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer (part 1) / Maños, Manuel (Hospital Universitari de Bellvitge) ; Giralt López de Sagredo, Jordi (Hospital Universitari Vall d'Hebron) ; Rueda Domínguez, Antonio (Hospital Costa del Sol (Marbella)) ; Cabrera, Joaquín (Hospital Infanta Cristina (Badajoz)) ; Martínez-Trufero, Javier (Hospital Universitario Miguel Servet (Saragossa)) ; Marruecos, Jordi (Institut Català d'Oncologia) ; López Pousa, Antonio (Institut d'Investigació Biomèdica Sant Pau) ; Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias) ; Castelo Fernández, Beatriz (Hospital Universitario La Paz (Madrid)) ; Martínez-Galán, Joaquina (Hospital Universitario Virgen de las Nieves (Granada)) ; Arias-De-La-Vega, Fernando Carrillo (Complejo Hospitalario de Navarra) ; Chaves, Manuel (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Herranz, Jesús (Complejo Hospitalario Universitario de A Coruña) ; Arrazubi, Virginia (Hospital de Basurto (Bilbao, Biscaia)) ; Basté, Neus (Hospital Universitari Vall d'Hebron) ; Castro, Almudena Vizcaya (Hospital Universitario La Paz (Madrid)) ; Mesía, Ricard (Institut Català d'Oncologia (L'Hospitalet de Llobregat)) ; Universitat Autònoma de Barcelona
Head and neck cancer is one of the most frequent malignances worldwide. Despite the site-specific multimodality therapy, up to half of the patients will develop recurrence. Treatment selection based on a multidisciplinary tumor board represents the cornerstone of head and neck cancer, as it is essential for achieving the best results, not only in terms of outcome, but also in terms of organ-function preservation and quality of life. [...]
2017 - 10.1016/j.oraloncology.2017.04.004
Oral Oncology, Vol. 70 (july 2017) , p. 58-64  

Artículos : Encontrados 749 registros   inicioanterior21 - 30siguientefinal  ir al registro:
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