Published articles

Published articles 1 records found  Search took 0.01 seconds. 
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11 p, 2.3 MB JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2 / Gubern Burset, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barceló Torns, Miquel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barneda, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López, José M. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Chalfant, Charles E. (Virginia Commonwealth University. School of Medicine) ; Balsinde, Jesús (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Balboa María A. (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The biogenesis of lipid droplets (LD) induced by serum depends on group IVA phospholipase A2 (cPLA2α). This work dissects the pathway leading to cPLA2α activation and LD biogenesis. Both processes were Ca2+-independent, as they took place after pharmacological blockade of Ca2+ transients elicited by serum or chelation with 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester). [...]
2009 - 10.1074/jbc.M109.061515
The Journal of biological chemistry, Vol. 284, Num. 47 (2009) , p. 32359-32369  

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