Published articles

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38 p, 1.1 MB BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS / Peluffo, Hugo (Institut Pasteur de Montevideo. Neuroinflammation Gene Therapy Laboratory) ; Unzueta Elorza, Ugutz (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Negro, Luciana (Institut Pasteur de Montevideo. Neuroinflammation Gene Therapy Laboratory,) ; Xu, Zhikun (CIBER en Bioingeniería, Biomateriales y Nanomedicina) ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The increasing incidence of diseases affecting the central nervous system (CNS) demands the urgent development of efficient drugs. While many of these medicines are already available, the Blood Brain Barrier and to a lesser extent, the Blood Spinal Cord Barrier pose physical and biological limitations to their diffusion to reach target tissues. [...]
2015 - 10.1016/j.biotechadv.2015.02.004
Biotechnology advances, Vol. 33 Núm. 2(Març-Abril 2015) , p. 277-287
5 documents

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