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15 p, 1.6 MB Quantifying conformational changes in GPCRs : glimpse of a common functional mechanism / Dalton, James A.R. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lans, Isaias (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
Background: G-protein-coupled receptors (GPCRs) are important drug targets and a better understanding of their molecular mechanisms would be desirable. The crystallization rate of GPCRs has accelerated in recent years as techniques have become more sophisticated, particularly with respect to Class A GPCRs interacting with G-proteins. [...]
2015 - 10.1186/s12859-015-0567-3
BMC Bioinformatics, Vol. 16 N. 124 (April 2015) , p. 1-15  

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