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10 p, 638.7 KB Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions / Carnicer Heras, Marc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Ten Pierick, Angela (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; van Dam, Jan (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Heijnen, Joseph J. (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d’Enginyeria Química, Biològica i Ambiental) ; van Gulik, Walter (Delft University of Technology. Department of Biotechnology (Delft, Països Baixos)) ; Ferrer i Alegre, Pau (Universitat Autònoma de Barcelona. Departament d’Enginyeria Química)
Background: Environmental and intrinsic stress factors can result in the global alteration of yeast physiology, as evidenced by several transcriptional studies. Hypoxia has been shown to have a beneficial effect on the expression of recombinant proteins in Pichia pastoris growing on glucose. [...]
2012 - 10.1186/1475-2859-11-83
Microbial cell factories, Vol. 11, N. 83 (June 2012) , p. 1-10
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