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25 p, 6.2 MB Poly(Adp-ribose) binding and macroh2a mediate recruitment and functions of kdm5a at dna lesions / Kumbhar, Ramhari (University of Texas at Austin) ; Sanchez, Anthony (University of Texas at Austin) ; Perren, Jullian (University of Texas at Austin) ; Gong, Fade (Baylor College of Medicine) ; Corujo, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Medina, Frank (University of Texas at Austin) ; Devanathan, Sravan K. (University of Texas at Austin) ; Xhemalce, Blerta (University of Texas at Austin) ; Matouschek, Andreas (University of Texas at Austin) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buck-Koehntop, Bethany A. (University of Utah) ; Miller, Kyle M. (University of Texas at Austin) ; Universitat Autònoma de Barcelona
The histone demethylase KDM5A erases histone H3 lysine 4 methylation, which is involved in transcription and DNA damage responses (DDRs). While DDR functions of KDM5A have been identified, how KDM5A recognizes DNA lesion sites within chromatin is unknown. [...]
2021 - 10.1083/jcb.202006149
The journal of cell biology, Vol. 220 Núm. 7 (2021) , p. e202006149  

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